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Scientists see positive results from 1st ever gene editing therapy

A second patient has been treated in a historic gene editing study in California, and no major side effects or safety issues have emerged from the first man’s treatment nearly three months ago, doctors revealed Tuesday.
- Source: NYPost
- 531
- February 7, 2018
gene editing Gene therapy New Approvals
BMS’ Opdivo and Yervoy combo better than chemo in halting lung cancer progression

Bristol-Myers Squibb has revealed promising data from its ongoing Phase 3 study investigating the efficacy of Opdivo (nivolumab) in combination with Yervoy (ipilimumab) compared to chemotherapy in the first-line treatment of advanced non-small-cell lung cancer (NSCLC) in patients whose cancers have a high tumour mutation burden (TMB), regardless of PD-L1 expression.
- Source: pharmafile
- 593
- February 7, 2018
BMS Chemotherapy NSCLC Opdivo TMB Yervoy
The future of lung function tests for COPD

With the global increase of lung diseases such as asthma, severe bronchitis and emphysema, lung function tests are becoming a bigger concern for many people.
- Source: Ddu
- 1,519
- February 7, 2018
COPD Ddu College Spirometry
Why AstraZeneca’s New Drug Strategy Seems to be Bearing Fruit

Pharma giant AstraZeneca has seen a fourfold increase in research productivity following a narrowing of disease focus and cuts in laboratory and staff over the past seven years, Reutersreported Thursday.
- Source: china-pharmacy
- 522
- February 7, 2018
AstraZeneca New Drug Strategy
Drug Safety Communication – Boxed Warning Added To Highlight Correct Dosing

FDA is warning that the liver disease medicine Ocaliva (obeticholic acid) has been incorrectly dosed daily instead of weekly in patients with moderate to severe primary biliary cholangitis (PBC), a rare chronic liver disease, increasing the risk of serious liver injury. To ensure correct dosing and reduce the risk of liver problems, FDA is clarifying the current recommendations for screening, dosing, monitoring, and managing PBC patients with moderate to severe liver disease taking Ocaliva. FDA is adding a new Boxed Warning, FDA’s most prominent warning, to highlight this information in the prescribing information of the drug label. FDA is also requiring a Medication Guide for patients to inform them about this issue.
- Source: fda
- 617
- February 6, 2018
Boxed Warning FDA liver disease Ocaliva PBC
Insightec closes $150m Series E

HAIFA, Israel and MIAMI, Florida – INSIGHTEC®, a commercial-stage medical technology company revolutionizing surgery with incisionless MRI-guided focused ultrasound (MRgFUS) announced today the closing of a $150 million Series E private equity investment round. Koch Disruptive Technologies (KDT), a subsidiary of Koch Industries, focused on finding and funding innovative and emerging companies, led the round with a $100 million investment.
- Source: drugdu
- 541
- February 6, 2018
Market Views MRgFUS non-invasive treatments
Ultrasound tech genetically controls cells to kill cancer new study finds

Researchers say the approach breaks new ground in treating cancer non-invasively and with unprecedented precision.
- Source: Healthcare IT news
- 626
- February 6, 2018
cancer CAR–T immunotherapy Researches
Nicotine in E-cigarettes damages DNA, mouse study suggests

The nicotine in e-cigarettes seems to damage DNA in ways that may increase cancer risk, a new study in mice suggests.
- Source: medicalxpress
- 646
- February 6, 2018
cancer DNA e-cigarettes nicotine Researches
Empatica’s consumer-facing epileptic seizure-detecting wearable gets FDA clearance

Emaptica's Embrace, the consumer-facing wearable for epileptic seizure detection, received 510(k) clearance from the FDA last month. The wearable, which has already been used in clinical trials by pharma company Sunovion, has a long history that's led it up to this milestone.
- Source: MobiHealthNews
- 803
- February 6, 2018
digital health epilepsy medical device New Approvals
Edible QR medication could help doctors prescribe more accurately, keep patients more informed

It's not uncommon to see customers paying for coffee or boarding a flight using a QR code from their smartphone, but some researchers are now looking to create an edible medication QR code. Researchers at the University of Copenhagen recently published a study in the International Journal of Pharmaceutics which looks at creating QR-encoded smart oral medication made by inkjet printing.
- Source: MobiHealthNews
- 526
- February 6, 2018
digital health medtech mHealth Researches

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