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Global orthopedic giant CEO may be dismissed

Recently, according to the Mail on Sunday report in the UK, global orthopedic giant Smith&Nephew has received a stern warning from shareholders due to poor performance. Smith&Nephew’s shareholders have lost patience with CEO Deepak Nath’s strategic development speed, claiming that if the company’s performance cannot be improved, Deepak Nath will be dismissed and Smith&Nephew will also face the splitting of its orthopedic department internally. It is reported that the stock price of Xerox Hui has dropped by up to 44% in the past five years. With this year’s performance still not “clear up”, the emotions of shareholders are difficult to calm, further putting pressure on Deepak Nat. Century old enterprises face crisis Shi Lehui was founded in the UK in 1856, a well-established company with over a hundred years of history. Its main businesses include orthopedics, sports medicine and otolaryngology, and advanced wound management. Currently, Shi Lehui is at the ...
- Source: drugdu
- 34
- November 15, 2024
Johnson&Johnson Medical Technology, organizational restructuring

Recently, Johnson&Johnson Medical Technology has made organizational adjustments to its surgical division. Starting from January 1, 2025, the Surgery Division will be reorganized into six major departments: Minimally Invasive and Energy Surgery Division, Wound Closure Division, Biosurgery Division, Surgical Product Expansion Division (i.e. Wide Area Market Division), Strategic Marketing Division, and Robotics and Digitalization Division. 01. Adjustment of the Organizational Structure of the Surgical Division Given the rapid changes in policy environment and the new trend of market competition, Johnson&Johnson Medical Technology firmly believes that the Surgical Division’s continued leadership in the market in the new era is an important cornerstone for winning the Chinese market and the future. To this end, the company has launched the “Yaoying 2030” surgical division strategy, aiming to accelerate the transformation of the GTM model and cover more customers and patients with better and faster services. In the new stage of development, Johnson&Johnson Medical ...
- Source: drugdu
- 36
- November 15, 2024
Uncovering the truth of AbbVie’s $8.7 billion lesson

M&A is a metaphysics, with heaven on one side and hell on the other, tempting prominent names to enter. The latest to enter “hell” is AbbVie. On November 11, AbbVie announced that emraclidine, the “ace project” acquired by acquiring Cerevel for $8.7 billion at the end of last year, failed to reach the expected endpoint in two Phase II studies for schizophrenia, which cast a shadow on its future. As soon as the news came out, AbbVie’s stock price plummeted 12.57%, and its market value evaporated by more than $40 billion overnight. Once, this merger and acquisition was a “model” in the industry. From the first acquisition invitation to the final acquisition of Cerevil, AbbVie took less than two months. Fast, accurate, and ruthless, it foreshadowed AbbVie’s determination to deal with the patent cliff. But now, everything is coming to nothing. This once again allows us to see the “variables” ...
- Source: drugdu
- 30
- November 15, 2024
Hospitals have a 152-day payment period, and many places have taken action to manage it

On November 11, the National Medical Insurance Administration and the Ministry of Finance jointly issued the “Notice on Doing a Good Job in Prepayment of Medical Insurance Funds”, which clearly stated that a prepayment system should be established, which will be used specifically for medical expenses such as the purchase of drugs and medical consumables. The prepayment scale of medical insurance prepayments is about 1 month, and it shall not be used for non-medical expenses such as medical institution infrastructure investment, daily operation, and debt repayment. For a long time, the “difficulty in collecting payments” in hospitals has been a “long-standing” problem that pharmaceutical companies have to face. Especially after the epidemic, the income of some medical institutions has been affected, and the problem of capital shortage is obvious. After receiving local financial subsidies, they often choose to ensure the core operating funds first and delay the payment of procurement ...
- Source: drugdu
- 30
- November 15, 2024
374-year-old Chinese time-honored brand will change hands

On November 12, ST Jiuzhi issued a “Notice on the Transfer of Equity by the Controlling Shareholder and the Proposed Change of Control and Equity”. On November 10, Li Zhenguo, the controlling shareholder and actual controller of Jiuzhitang, signed the “Share Transfer Agreement on Jiuzhitang Co., Ltd.” with Heilongjiang Chenneng University of Technology Venture Capital, stipulating that Li Zhenguo will transfer his 6.25% stake in Jiuzhitang to Chenneng Venture Capital, and the total transfer amount of the target shares is about 385 million yuan. After the transfer is completed, Chenneng Venture Capital will become the controlling shareholder of ST Jiuzhi, with a controlling proportion of 24.04%, and the Heilongjiang Provincial State-owned Assets Supervision and Administration Commission will become the actual controller of ST Jiuzhi. Li Zhenguo holds 18.19% of ST Jiuzhi’s shares, making him the second largest shareholder. Specific changes in equity: It is worth mentioning that there were early ...
- Source: drugdu
- 31
- November 15, 2024
15%! AstraZeneca’s revenue in China exceeded 35 billion in the first nine months

AstraZeneca disclosed its financial report for the first three quarters of 2024 on November 12. The company’s revenue was 39.182 billion US dollars, a year-on-year increase of 19%; of which product revenue was 37.576 billion US dollars, a year-on-year increase of 19%. AstraZeneca raised its full-year performance guidance for 2024 in the announcement, and it is expected that both full-year revenue and core earnings per share will achieve high-ten-digit percentage growth, which was previously expected to be in the mid-ten digits. From the perspective of regional distribution, the Chinese market has undoubtedly become an important engine for AstraZeneca’s performance growth. In the first three quarters of 2024, AstraZeneca’s revenue in China reached more than 5 billion US dollars (equivalent to more than 35 billion yuan in RMB), accounting for about 13% of its global market share, becoming an important part of AstraZeneca’s global business. Many people may have no idea ...
- Source: drugdu
- 27
- November 15, 2024
【EXPERT Q&A】What should I pay attention to when IVD uses overseas clinical trial data?

Drugdu.com expert’s response: When using overseas clinical trial data for IVD (In Vitro Diagnostic) products, attention should be paid to the following aspects: Ⅰ. Data Quality and Integrity Ensuring Data Accuracy: Utilize validated data collection tools and methods, such as Electronic Data Capture (EDC) systems. Implement a double-entry and verification mechanism to reduce human entry errors. Conduct regular data consistency checks and logical checks to identify and correct abnormal values and errors. Ensuring Data Integrity: Maintain detailed records and traceability from trial design to data collection, processing, and analysis. Ensure that all relevant data is collected completely without omissions. Ⅱ. Data Compliance Adhering to Relevant Regulations and Guidelines: Understand and comply with the regulations and guidelines for in vitro diagnostic reagents in the target market (e.g., the European Union, the United States, etc.). For instance, the IVDR (In Vitro Diagnostic Medical Devices Regulation) of the European Union has specific requirements for clinical trial data. Ethical Review: Ensure that ...
- Source: drugdu
- 29
- November 15, 2024
Sichuan Kelun Pharmaceutical Co., Ltd. has been approved for the submission of avatranib maleate tablets

On November 11th, according to the latest announcement on the NMPA official website, Sichuan Kelun Pharmaceutical Co., Ltd. approved the submission of avatranipal maleate tablets. Since the beginning of this year, 24 varieties of Kelun Pharmaceutical (including its subsidiaries) have been evaluated. The original research and development company of Avastin Maleate Tablets is AkaRx, a company based in the United States. It is the world’s first oral thrombopoietin receptor agonist (TPO-RA) approved by the US Food and Drug Administration (FDA) for chronic liver disease-related thrombocytopenia, mainly suitable for adult patients with chronic liver disease-related thrombocytopenia undergoing elective diagnostic procedures or surgery. According to the database, the sales revenue of Avastin Maleate Tablets in the national in-hospital market exceeded 500 million yuan in 2023, with a year-on-year growth of 40.97%. Previously, there were 8 pharmaceutical companies in China, including Qilu Pharmaceutical, Chengdu Beite Pharmaceutical, and Nanjing Zhengda Tianqing Pharmaceutical, that had ...
- Source: drugdu
- 38
- November 14, 2024
Johnson&Johnson’s first PFA product receives FDA approval for market launch

Recently, Johnson&Johnson announced that it has received approval from the US Food and Drug Administration (FDA) for its Varipulse pulsed field ablation system, which can be used to treat drug-resistant paroxysmal atrial fibrillation. After obtaining approval, Johnson&Johnson became the third company in the United States to have PFA technology for treating AFib, joining the ranks of Medtronic and Boston Scientific, and the PFA market’s top three competition officially opened. With the support of an ace, Johnson&Johnson has strong competitive strength It is understood that the Varipulse pulsed field ablation system consists of a Varipulse ablation catheter and a TRUPULSE generator. Among them, the VARIPULSE ablation catheter was developed based on Johnson&Johnson’s previous mapping catheter LASSO catheter, which is a continuation of LASSO catheter technology and further demonstrates Johnson&Johnson’s deep technical reserves in the catheter field. The Varipulse ablation catheter has 10 electrodes on the annular tip, and the size of ...
- Source: drugdu
- 38
- November 14, 2024
270 million! Chinese medicine giant acquires 100% equity of innovative pharmaceutical company

Chinese medicine companies are beginning to acquire innovative pharmaceutical companies. 01 270 million yuan Kangyuan Pharmaceutical acquires 100% equity of Zhongxin Pharmaceutical On November 7th, Kangyuan Pharmaceutical released an announcement on the acquisition of 100% equity of Jiangsu Zhongxin Pharmaceutical Co., Ltd. and related party transactions. It plans to acquire 100% equity of Zhongxin Pharmaceutical with its own funds of 270 million yuan. After the completion of this transaction, Zhongxin Pharmaceutical will become a wholly-owned subsidiary of Kangyuan Pharmaceutical.In this transaction, Kangyuan Pharmaceutical’s controlling shareholder Kangyuan Group holds 70% equity of Zhongxin Pharmaceutical, corresponding to a transfer price of 189 million yuan. Kangyuan Pharmaceutical will make the first payment of 60%, or 113.4 million yuan, to Kangyuan Group, and the remaining 40%, or 75.6 million yuan, will be paid in installments after the corresponding pipeline drugs of Zhongxin Pharmaceutical obtain marketing authorization. Nanjing Kangzhu Enterprise Management Partnership (Limited Partnership) holds ...
- Source: drugdu
- 32
- November 14, 2024

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