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Poco acquires electrophysiology company

On November 4, local time, Boston Scientific announced that it had reached a final agreement to acquire Cortex, Inc. Subject to customary closing conditions, Boston Scientific expects to complete the transaction in the first half of 2025. The transaction is expected to have an immaterial impact on adjusted earnings per share in 2025 and is expected to be slightly dilutive on a GAAP basis due to amortization expenses and acquisition-related net expenses. The specific terms of the transaction have not been disclosed. Cortex is a young private medical technology company announced and funded by Ajax Health in December last year. The company develops integrated mapping and ablation solutions for the treatment of atrial fibrillation (AFib). At that time, Cortex had received a $90 million financing commitment, led by KKR and Hellman & Friedman (H&F), and other investors included AI Life Sciences, a subsidiary of Access Industries. Cardiac ablation has become ...
- Source: drugdu
- 48
- November 7, 2024
Kejun Pharmaceuticals Completes B+ Round of Phased Financing

On October 31, Shanghai Kejun Pharmaceutical Technology Co., Ltd. (hereinafter referred to as “Kejun Pharmaceutical”) announced the completion of its B+ round of phased financing. This round of financing was led by Guoxin Innovation Equity, and other major investors included Aeon Group and Infinity Capital, and the original investor Honghai Capital also continued to make additional investments. Qidian Capital served as the financial advisor for this round of financing and will continue to provide financing services to Kejun Pharmaceutical in the future. Kejun Pharmaceutical stated that the funds raised from this financing will be used to accelerate the clinical development of CG-0255, a core product in the cardiovascular field. About Kejun Pharmaceutical Kejun Pharmaceutical was established in Zhangjiang, Shanghai in 2018, focusing on the treatment of cardiovascular and cerebrovascular diseases and antiviral diseases, and focusing on the research and development of small molecules and nucleic acid drugs. At present, Kejun ...
- Source: drugdu
- 50
- November 7, 2024
Analytica Vietnam

Organiser：Messe München GmbH (Munich Exhibition Center) Time：April 2nd – 4th, 2025 Address：Plot No. 23 – 25 & 27 – 29, Knowledge Park – II, Gautam Budh Nagar, Greater NOIDA – 201306 Exhibition hall：Saigon Exhibition and Convention Center (SECC) Product range: Medical Products: Medical equipment and instruments, medical consumables, medical dressings, surgical equipment, emergency rescue equipment, diagnostic equipment and supplies, ophthalmic instruments and equipment, ENT equipment, dental equipment and supplies, medical reagents and equipment, medical healthcare products and equipment, medical institution and laboratory technology equipment, medical information and technology exchange, beauty instruments. Analytical Instruments: Optical analytical instruments, mass spectrometers, spectroscopes, chromatographs, spectrographs, spectrometers, electrochemical analytical instruments, ray analytical instruments, gas chromatographs, liquid chromatographs, thermal analytical instruments, various portable instruments, surface analytical instruments, nuclear analytical instruments, elemental analytical instruments, process analytical instruments, compositional analytical instruments, injection analytical instruments, and other general analytical instruments. Laboratory Equipment: Laboratory instruments and equipment, laboratory automation ...
- Source: drugdu
- 63
- November 7, 2024
Design multi state and functional proteins using sequence space diffusion model

Protein Denoising Diffusion Probabilistic Models (DDPM) can efficiently generate novel proteins that meet specific properties and functional requirements, and have significant value in the field of protein design. Although many current models, such as RFdiffusion and Chroma, have shown excellent performance in generating protein three-dimensional structures, there are still challenges in generating proteins with sequence specificity and functional properties, and these models often require a lot of time and computational resources for training. David Baker’s team at the University of Washington has proposed a new solution to address this challenge. They believe that diffusion in sequence space can more effectively learn more knowledge from the current large amount of protein sequence data. Therefore, the research team developed a sequence space diffusion model ProteinGenerator based on RoseTTAFold, which can generate protein sequences and structures that meet the required properties. Subsequently, the research team further successfully designed multiple proteins with different functions ...
- Source: drugdu
- 51
- November 6, 2024
5 innovative drugs included in breakthrough treatment varieties

Breakthrough treatment varieties refer to innovative drugs or improved new drugs used to prevent and treat diseases that seriously endanger life or seriously affect quality of life, and for which there are no effective prevention and treatment methods or sufficient evidence to show significant clinical advantages compared to existing treatment methods. After obtaining this recognition, it can accelerate the review process, accelerate the drug development process, and solve the unmet clinical needs of patients. In the past October, the CDE official website plans to include 5 breakthrough therapy varieties, including 1 therapeutic vaccine, 3 ADC drugs, and 1 monoclonal antibody drug. The following are introductions to 5 innovative drugs for reference only. 1. TVAX-008: Hepatitis B On October 14th, Nanjing Yuanda Weixin Biopharmaceutical Co., Ltd. TVAX-008 applied to be included in the breakthrough treatment category, suitable for the treatment of chronic hepatitis B virus (HBV) infection. TVAX-008 is a therapeutic ...
- Source: drugdu
- 68
- November 6, 2024
Two innovative medical devices have been approved for market launch

Recently, the National Medical Products Administration announced the approval of the registration applications for two innovative products, Yabonixi Medical Technology (Suzhou) Co., Ltd.’s “knee joint prosthesis system” and Shanghai Xinwei Medical Technology Co., Ltd.’s “intracranial aneurysm embolization assisted stent”. Yabonixi Medical offers freedom of movement in all aspects Yabonixi Medical is a wholly-owned subsidiary of Jiaoying Medical Equipment (Shanghai) Co., Ltd., dedicated to the research, development, production, and sales of high-end orthopedic medical equipment, minimally invasive surgical medical equipment, and more. Yabonixi Medical was founded by Dr. Yao Jianqing, a leading figure in the international orthopedic field. It is reported that Yao Jianqing is an experienced veteran in the field of medical devices, with 36 years of rich experience in medical device and tissue engineering research and industrialization. He has served as the Global R&D Senior Director and Asia Pacific R&D Senior Director of ZimmerBiomet, a joint company. Yao Jianqing ...
- Source: drugdu
- 54
- November 6, 2024
【EXPERT Q&A】What are medical device quality management system nonconformities?

Drugdu.com expert’s response: Non-conformities in the quality management system for medical devices refer to situations where an activity or its outcome in the quality management system activities related to medical device production, sales, and after-sales service fails to meet established requirements or standards. These requirements or standards typically originate from relevant regulations, standards, contracts, and internal quality management system documents of the enterprise. Non-conformities can manifest in various forms, including but not limited to non-conformities related to documents, products, processes, personnel, environments, records, and data. Specifically, non-conformities in the quality management system for medical devices may involve the following aspects: Document Non-conformity: Quality management system documents do not comply with applicable laws, regulations, standards, or contracts. For instance, there may be no documented corrective action control procedure established, no clear review of nonconformities (including customer complaints), no determination of the causes of nonconformities, no evaluation of measures needed to ensure ...
- Source: drugdu
- 58
- November 6, 2024
Another GLP-1 drug king, is it on the way?

Recently, the Q3 financial reports of MNCs have been released one after another, and some are happy and some are sad. When a number of MNCs began to lower their full-year EPS, Amgen’s Q3 financial report earnings gave a high score answer sheet. Among them, Amgen’s total revenue in the third quarter increased by 23%, and its GAAP net earnings per share (EPS) increased by 62% year-on-year, from US$3.22 to US$5.22. What is more imaginative is that with the data catalysis of the new macromolecular weight loss drug AMG133, this macromolecular antibody that goes against the grain and antagonizes GIPR may become Amgen’s next gold mine. According to Amgen’s Q3 2024 financial report, the most significant year-on-year growth is LUMAKRAS (AMG510) – a targeted drug for KRASG12C mutation-positive lung cancer. The sales ceiling of this gene mutation in European and American countries will be much higher than that in Asian ...
- Source: drugdu
- 59
- November 6, 2024
China’s time-honored brands, mergers and acquisitions accelerate

Recently, Beijing Tong Ren Tang issued an announcement on foreign investment, stating that its holding subsidiary Beijing Tong Ren Tang Commercial intends to sign a “Share Transfer Agreement” with Honghui Technology, Daopei Hongde, Honghui Pharmaceutical, Wang Desheng and Wang Aixiao, and intends to pay about 105 million yuan to acquire Honghui Technology’s 51% stake in Honghui Pharmaceutical. As a pharmaceutical and medical device operating company, Honghui Pharmaceutical was established in 1994 and is mainly engaged in pharmaceutical research and development, pharmaceutical production and sales, and medical device operations. The performance in the first half of 2024 showed that Honghui Pharmaceutical achieved revenue of 844 million yuan and net profit of 25.5713 million yuan (unaudited). In 2023, Honghui Pharmaceutical achieved a net profit of 228 million yuan (unaudited). At present, Honghui Pharmaceutical is still a long way from catching up with last year’s full-year net profit. Tong Ren Tang is a ...
- Source: drugdu
- 60
- November 6, 2024
NMN can prevent physical decline and poor sleep

Walking speed reflects the vitality of the muscles, bones, nerves and cardiovascular system, so our walking speed can also predict our lifespan. After the age of 65, our walking speed gradually decreases, and eventually our daily life will be affected, greatly reducing our quality of life. Therefore, it is very important to keep muscles, bones, nerves and heart healthy through endurance and resistance training. Exercise may be the best way to prevent slow walking. However, poor sleep quality and low energy levels may prevent many people from sticking with exercise. In addition, poor sleep quality and fatigue may be the cause of low NAD+ levels. Recently, Japanese scientists published a research article titled “Ingestion of β-nicotinamide mononucleotide increased blood NAD levels, maintained walking speed, and improved sleep quality in older adults in a double-blind randomized, placebo-controlled study” in the journal “GeroScience”. The results showed that supplementing NMN can prevent physical ...
- Source: drugdu
- 54
- November 6, 2024

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