The launch of new drugs seems to solve some clinical unmet problems, and theoretically, it seems to help improve the overall health of everyone. However, a recent paper published in The Lancet arrived at the opposite conclusion. They believe that over the past two decades, the funds used by the UK’s National Health Service (NHS) for newly approved drugs could actually bring more health benefits if they were instead invested in existing services. Investigation on NICE Database Researchers from the UK and the US first reviewed UK drug technology assessments published in the NICE (National Institute for Excellence in Healthcare Services) public database between 2000 and 2020. After investigating 183 drugs evaluated for 385 indications out of 339 evaluations in NICE’s new drug evaluation, they found that the median gain in quality adjusted life years (QALYs) was 0.49 throughout the entire evaluation, with moderate dispersion. Quality adjusted lifespan is an ...
On December 31, 2024 Eastern Time, Baird Medical Investment Holdings Ltd surged 623.81%. Baird Medical Investment Holdings Limited (hereinafter referred to as “Baird Medical”) is the substantive holding company of Baird (Suzhou) Medical Co., Ltd. Baide Medical officially went public on NASDAQ in the United States on October 2, 2024, through the backdoor acquisition of SPAC (Special Purpose Acquisition Company) ExcelFin Acquisition (XFIN). Baide Medical is a leading microwave ablation medical enterprise in China. According to the data, based on the sales revenue and sales of microwave ablation needles in 2022, Baide Medical ranks first among the suppliers of microwave ablation medical equipment for treating thyroid nodules and breast lumps in China. In addition, based on sales revenue in 2022, the company is the third largest supplier of microwave ablation medical devices in China. 01. After being listed for 3 months, the stock is like riding a roller coaster On ...
Cells naturally process various classification cues, such as stress and developmental signals, to initiate cellular functions and produce different outcomes; Immune cells respond to threats based on detected signals; The p53 signaling pathway determines whether to repair damage or initiate self destruction to prevent cancer. Scientists have been working hard to create artificial systems that can replicate this decision-making process within cells. Most existing attempts rely on DNA or RNA, which require further translation into proteins to perform their functions, resulting in a slow and less direct process. Recently, researchers from Westlake University and California Institute of Technology have not used DNA or RNA based systems, but have designed a fully protein based system in living cells, consisting of de novo designed protein heterodimers and engineered viral proteases to construct decision circuits that can process multiple signals and make decisions based on these signals. The research team named the system ...
New York (Reuters) – The U.S. Federal Court of Appeals for the Second Circuit has reinstated a lawsuit against Novartis. The lawsuit was filed by Steven Camburn, a former Novartis sales representative, alleging that Novartis illegally paid kickbacks to doctors to induce them to promote its multiple sclerosis drug Gilenya. Camburn said Novartis paid doctors thousands of dollars and set up business banquets in high-end restaurants to let them speak at events that were nominally academic conferences but were actually social activities to promote Gilenya. ▍Reported many times In 2013, the whistleblower sued Novartis under the U.S. False Claims Act, claiming that it paid $3,500 to doctor speakers at academic events to promote the sales of Gilenya. However, the lawsuit was dismissed, and the whistleblower filed lawsuits in other courts many times afterwards. But they all failed due to lack of sufficient specific evidence. But this time, the pharmacist’s complaint ...
On the evening of January 2, the State Food and Drug Administration conditionally approved the listing of Amymetocel injection applied by Bosheng Excellence Biotechnology (Beijing) Co., Ltd. (hereinafter referred to as “Bosheng Excellence”) through the priority review and approval procedure. This is China’s first stem cell therapy drug, used to treat acute graft-versus-host disease with failure of hormone therapy, mainly involving the digestive tract in patients over 14 years old. Graft-versus-host disease is one of the main complications after allogeneic hematopoietic stem cell transplantation, and may cause death in severe cases. Specifically, graft-versus-host disease is a type of multi-organ syndrome that occurs after allogeneic hematopoietic stem cell transplantation when lymphocytes from the donor attack the recipient’s tissues, manifested as tissue inflammation and fibrosis mainly involving the skin, gastrointestinal tract, liver, lungs and mucosal surfaces. Amymetocel injection is a human umbilical cord mesenchymal stem cell injection. Its listing provides a new ...
The results of the third batch of centralized procurement of Chinese patent medicines by the Procurement Alliance for Procurement of Produced Medicines were announced recently, and the price reduction of centralized procurement exceeded market expectations. This round of centralized procurement of Chinese patent medicines involves 20 product groups, and the purchased varieties are mainly Chinese patent medicines that are commonly used in clinical practice, with high purchase amounts and large usage, including oral Chinese patent medicines and Chinese medicine injections. According to the results of the proposed selection announced by the Hubei Medical Security Bureau, a total of 175 products are proposed to be selected, of which 165 are directly proposed to be selected and 10 are supplementary proposed to be selected. The Hubei Medical Security Bureau did not directly announce the average price reduction of the selected varieties, but according to the statistics of different brokerages, the average price ...
On January 2, it was learned that in response to the online reports that relevant personnel of the First People’s Hospital of Datong City, Shanxi Province were suspected of participating in the sale of babies, Datong City set up a joint investigation team to conduct an investigation. Any violations of laws and disciplines found will be dealt with seriously in accordance with the law and discipline. According to @Fazhi Daily, it is reported that the doctor involved is Wang Mouqing, chief physician of the obstetrics department of the First Hospital of Datong City, Shanxi Province. In 2022, Wang Mouqing received a 15-year-old girl who was about to give birth, but the girl’s family did not want the child. At the same time, another couple who had failed to conceive after two IVF treatments also visited Wang Mouqing. Faced with this situation, Wang Mouqing introduced the two parties. In May of ...
Organiser:Informa Markets Time:September 2 – 4, 2025 Address:Convention Square 1, Lower Long Street, Cape Town 8001 Exhibition hall:Cape Town International Convention Centre (CTICC) Product range: Medical Devices: Laboratory equipment and configurations, emergency and transportation facilities, surgical equipment, nursing and monitoring equipment, etc. Medical Technologies: Orthopedic and rehabilitation technologies, medical construction facilities and technologies, medical information and communication technologies, etc. Medicines: Various finished drugs, pharmaceuticals, medical excipients, etc. Hospital Consumables: Disposable medical products, medical disinfection products, etc. Medical Items: Medical clothing and laundry technologies, nutritional catering equipment, medical furniture, etc. About Africa Health: Africa Health in Cape Town, South Africa is the most important healthcare event on the African continent. Over the years, the mission and vision of our organization in Africa have been to bridge the gaps among healthcare business, knowledge, and skill development through meaningful connections, bringing the future of healthcare to the African continent and the ...
Drugdu.com expert’s response: Here is the English translation of the detailed summary of Germany’s measures for pharmaceutical regulation: Germany’s Measures for Pharmaceutical Regulation Germany’s measures for pharmaceutical regulation cover multiple aspects to ensure the safety, effectiveness, and accessibility of pharmaceuticals. The following is a detailed summary of Germany’s pharmaceutical regulation measures: Ⅰ. Pharmaceutical Management System Germany implements a joint regulatory system for the production and circulation of pharmaceuticals through federal and state pharmaceutical regulatory authorities. Federal Pharmaceutical Regulatory Authorities: These include the Federal Ministry of Health and Social Security, the Federal Institute for Drugs and Medical Devices (BfArM), the Federal Serum and Vaccine Institute, and the Federal Institute for Consumer Health Protection and Veterinary Medicine. Their main tasks include accepting pharmaceutical registration applications, issuing marketing authorization for pharmaceuticals, testing sera, vaccines, and experimental allergens, compiling pharmacopoeias, and issuing recall directives for pharmaceuticals suspected of having adverse health effects. State Pharmaceutical ...
Financial Update, January 1 – Seilong Pharmaceutical (002898) announced that its wholly-owned subsidiary, Hunan Seilong Pharmaceutical Co., Ltd., has recently received the approval notification for the listing application of Famotidine from the National Medical Products Administration. The valid period for this drug is 18 months, and the notification is effective until December 30, 2029, with a registration standard number of YBY77052024. Famotidine is primarily used to treat upper gastrointestinal bleeding caused by peptic ulcers, further enriching the company’s raw material pharmaceutical product pipeline. The company stated that specific production and sales conditions will be influenced by various internal and external environmental changes, which may lead to certain uncertainties. In the first three quarters of 2024, Seilong Pharmaceutical achieved revenue of 219 million yuan, with a net profit attributable to the parent company of -3.69 million yuan. https://finance.eastmoney.com/a/202501013284575136.html
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