On May 29, Fosun Pharma announced that its independently developed Class 1 new drug Ruvometinib Tablets (trade name: Fumainin®) was officially approved for marketing by the National Medical Products Administration (NMPA). As a highly selective MEK1/2 inhibitor, Fumainin was approved for two indications for the treatment of adult patients with Langerhans cell histiocytosis (LCH) and histiocytic tumors, and children and adolescents aged 2 years and above with neurofibromatosis type I (NF1) with symptomatic, inoperable plexiform neurofibromas (PN). Fosun Pharma’s Ruvometinib has been approved for marketing, filling the gap in the treatment of rare tumors such as adult LCH. It works by blocking key signaling pathways, with impressive clinical efficacy and safety, and subsequent research and development of multiple indications is worth looking forward to. https://www.nbd.com.cn/articles/2025-05-29/3893732.html
Drugdu.com expert’s response: The development of mRNA (messenger RNA) drugs has undergone a journey from early exploration to technological breakthroughs, and then to widespread application. The specific progression is as follows: I. Early Exploration (1961-1990) In 1961, scientists first discovered mRNA. In 1987, Malone found that mRNA molecules mixed with lipid droplets could enter cells and express the desired protein, marking the beginning of RNA research as a therapeutic agent. In 1990, scientists injected in vitro-transcribed messenger RNA (mRNA) into mice and discovered that it could be expressed in vivo, producing relevant proteins in a dose-dependent manner. This method of directly injecting mRNA could induce an immune response by expressing specific proteins, serving as the prototype for mRNA therapy. II. Technological Breakthroughs (Early 21st Century-2020) Entering the 21st century, mRNA synthesis, modification, and delivery technologies further advanced. In 2005, Karikó and Weissman discovered that using modified nucleotides like pseudouridine could ...
Jianfan Bio announced on the evening of May 28 that Jianfan Biotechnology Group Co., Ltd. recently received the ” Medical DeviceThe company’s new product, disposable waste liquid bag, has obtained the second-class medical device registration certificate. This new product is a waste liquid collection device during blood purification treatment. From January to December 2024, Jianfan Bio ‘s operating income structure is as follows: medical device manufacturing accounted for 99.71%, and others accounted for 0.29%. https://finance.eastmoney.com/a/202505283416906248.html
On May 28, Kangtai Biological issued an announcement that it received an acceptance notice issued by the National Medical Products Administration today, agreeing to accept the trivalent influenza vaccine jointly developed by the company and Lanzhou Bailing Biotechnology Co., Ltd.Clinical trial application for viral split vaccine (MDCK cells). The vaccine is suitable for people aged 3 years and above and is intended to stimulate the body to produce immunity against influenza viruses to prevent influenza caused by related types of influenza viruses. In the first quarter of 2025, Kangtai Biological achieved revenue of 645 million yuan and net profit attributable to shareholders of the parent company of 22.43 million yuan. 网址:https://finance.eastmoney.com/a/202505283416827087.html
Recently, Livzon Pharmaceutical announced that its wholly-owned overseas subsidiary LIAN SGP signed an agreement with the sellers (SK, Sunrise and KBA) to acquire 64.81% of the shares of Imexpharm Corporation (IMP), a Vietnamese listed company held by the sellers, at a purchase price of 573.08 billion Vietnamese dong (approximately RMB 1.587 billion). Public information shows that IMP is a leading pharmaceutical company in Vietnam, founded in 1977 and listed on the Ho Chi Minh City Stock Exchange in 2006. According to the list of the top ten well-known pharmaceutical companies in 2024 published by Vietnam Report Joint Stock Company (Vietnam Report), IMP ranked third. Imexpharm is mainly engaged in the research and development, production and sales of drugs, and its products mainly include antibiotics, cardiovascular and cerebrovascular drugs, etc. At present, Imexpharm has 4 factories and 25 retail branches in various provinces and cities in Vietnam. In terms of market ...
The 2025 ASCO Annual Meeting is about to be held. At present, the regular abstracts have been released to the public, and many domestic new drugs have performed well. Among them, LBL-007 of Weilizhibo has made its debut again with breakthrough data. This is the fifth consecutive year that the drug has been selected for the ASCO meeting. LBL-007 is a fully human IgG4 monoclonal antibody targeting LAG3. Its clinical progress ranks among the top three in the world (except for the only LAG3-targeted drug on the market). It is also the first antibody of its kind to be proven to be effective against nasopharyngeal carcinoma. Clinical data show that LBL-007 combined with first-line therapy for NPC patients has an ORR of 83.3% and a median PFS of 15.8 months, which is significantly higher than the existing standard regimen. With its excellent safety and efficacy, LBL-007 is expected to become ...
Organiser: Guangdong High-tech Enterprises Association Time:November 14th – 16th, 2025 address:Shenzhen World Exhibition & Convention Center (Bao’an New Hall), No. 1 Zhancheng Road, Fuhai Street, Bao’an District, Shenzhen City, Guangdong Province Exhibition hall:Shenzhen World Exhibition & Convention Center (Bao’an New Hall) Product range: Laboratory Technology and Equipment Zone: Microbial strains, incubation and cultivation equipment, culture media, high-throughput screening equipment, gene detection instruments, gene sequencing instruments, genetic engineering technology and equipment, separation and purification systems, bioprocess systems, fermenters, cell culture systems, cell reactors, bioreactors, GLP/GMP equipment, pre-treatment equipment, biochemical analysis instruments, measurement and control devices, bioinformatics technology, bio-imaging systems, biochips, reagents, preservation equipment, laboratory environmental equipment, laboratory information management systems, etc. Engineering Technology and Equipment Zone: Fermenters, bioreactors, cell reactors, enzyme reactors, cell culture equipment, culture media, saccharification equipment, filtration and separation equipment, extraction and purification equipment, mass transfer, evaporation and crystallization, drying, stirring, mixing, grinding, instrumentation and industrial automation ...
Pharmacogenomics studies how individuals respond to drugs based on their genetic code. Using that knowledge to guide prescribing in routine care could lead to better outcomes for patients and save money for health systems. Generating pharmacogenomic data in the laboratory is relatively straightforward, but a major challenge is making that information available to frontline healthcare professionals in a clinically relevant format and timeframe. This has meant that, to date, only a limited numbers of patients have been able to benefit from such individually optimised treatments. Dr. John McDermott, NIHR Academic Clinical Lecturer at the University of Manchester, Manchester, UK, will describe to the annual congress of the European Society of Human Genetics today (Tuesday) how he and colleagues, as part of the NHS-England Network of Excellence for Pharmacogenomics & Medicines Optimisation, have pioneered an approach to integrate genomic data into electronic health records in both GP practices and hospitals. This ...
Breakthrough MRI scans reveal hidden hypothalamic changes in young women, shedding light on the biological roots of anorexia and obesity, and paving the way for targeted treatments. A recent editorial feature published in the American Journal of Clinical Nutrition discusses the use of a novel imaging technique to investigate how certain structural features of the hypothalamus affect eating behaviors. A new approach to studying the hypothalamus Women are more likely to develop eating disorders like anorexia nervosa than men, particularly during puberty. Despite this disproportional occurrence, few studies have investigated the role of the female brain in neuroscience and psychiatry. The hypothalamus is a small, heterogeneous brain structure in the diencephalon that regulates homeostatic and hedonic functions involved in feeding behaviors. Current imaging techniques are limited in their ability to capture nuclei subsegmentation within the hypothalamus. As a result, most studies investigating the role of the hypothalamus have been conducted ...
No.1 Guangdong Province launches quantity based procurement, including 170 drugs and 248 product specifications Recently, the Guangdong Provincial Drug Trading Center issued a notice stating that 22 provinces (including the Corps) within the alliance will continue to purchase 170 varieties and 248 specifications of drugs, except for those that overlap with national procurement (including national joint procurement), national medical insurance negotiated drugs (including bidding drugs), and national basic medical insurance drug catalogs. This procurement has cancelled A/B purchase orders and opted for group bidding. Comment: Guangdong Province has launched a 22 province alliance drug procurement, involving 170 varieties. The A/B purchase orders have been cancelled and grouped for bidding, which may promote drug price reduction and industry integration. NO.2 Shandong Heda: The US Department of Commerce has preliminarily ruled that the anti-dumping tax rate obtained by the company’s wholly-owned subsidiary is 172.24% On the evening of May 26th, Shandong ...
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