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Natural products and herbal medicines show promise in fight against COVID-19

Researchers in China and the United States have called for more research into the potential prophylactic effects of natural products and herbal medicines on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and subsequent coronavirus disease 2019 (COVID-19). In an article recently published in the journal Frontiers in Pharmacology, the team discussed natural products that have exhibited an inhibitory effect on SARS-CoV-2 and herbal medicines that have been tested as potential therapies for COVID-19. “In this review, we aimed to provide a new perspective regarding COVID-19 prevention,” writes Jia-xu Chen from Jinan University in Guangzhou, and colleagues from the University of Houston, and the University of California. The researchers suggest that while the world awaits effective treatments and a commercially available vaccine, the repurposing of natural products and herbal medicines as prophylactics represents a promising approach to at least slow the transmission of SARS-CoV-2. “In the interest of public health, this ...
- Source: drugdu
- 1,337
- November 18, 2020
Covid-19
Poor nutrition in school years may have created 20 cm height gap across nations

A new global analysis led by Imperial College London, and published in journal The Lancet, has assessed the height and weight of school-aged children and adolescents across the world. The study, which used data from 65 million children aged five to 19 years old in 193 countries, revealed that school-aged children’s height and weight, which are indicators of their health and quality of their diet, vary enormously around the world. There was a 20 cm difference between 19-year-olds in the tallest and shortest nations — this represented an eight-year growth gap for girls, and a six-year growth gap for boys. For instance, the study revealed that the average 19-year-old girl in Bangladesh and Guatemala (the nations with the world’s shortest girls) is the same height as an average 11-year-old girl in the Netherlands, the nation with the tallest boys and girls. The international team behind the study warn that highly variable ...
- Source: drugdu
- 284
- November 16, 2020
height nutrition
Discovery of novel hidden gene in SARS-CoV-2

Understanding the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the virus that causes the coronavirus disease 2019 (COVID-19) – is crucial for both vaccine and treatment development. Since the pandemic started in December 2019, many studies have explored the virus’s origins and how it infects humans. This way, scientists and clinicians have an idea of how to combat the infection. A team of researchers from Germany, Taiwan, and the United States has identified and characterized a new hidden gene in SARS-CoV-2 that is also present in Guangxi pangolin coronaviruses – though, curiously, absent in closely related pangolin and bat coronaviruses. What are overlapping genes? The coronavirus pandemic raises urgent questions about the properties that allow viruses in animals to jump to humans. Called zoonosis, these types of diseases have impacted human life for years, including the AH1N1 virus, bovine tuberculosis, glanders, and bubonic plague, among others. To further understand zoonotic diseases, ...
- Source: drugdu
- 279
- November 14, 2020
Covid
Severe COVID-19 linked to age, body mass index and ABO blood group

With the COVID-19 pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infecting over 50 million people worldwide with hundreds of thousands experiencing severe respiratory illness, researchers have been trying to find the factors associated with severe disease. From the start of the pandemic in March this year, several studies have indicated heart disease, high blood pressure, diabetes, obesity, etc. could be linked to severe disease. Now German researchers have published a study on the association between severe respiratory infection caused by SARS CoV-2 and factors such as age, body mass index (BMI) and ABO blood group. Their study titled, “Severity of Respiratory Infections due to SARS-CoV-2 in Working Population: Age and Body Mass Index Outweigh ABO Blood Group,” was released prior to peer review on the preprint site medRxiv*. Background There is a rise in cases of COVID-19, and there is a lack of consensus regarding the high-risk ...
- Source: drugdu
- 120
- November 13, 2020
Covid-19
Anvisa suspende temporariamente teste da vacina CoronaVac, que será produzida pelo Butantan

Interrupção foi determinada após ‘evento adverso grave’, segundo a agência. Em entrevista à TV Cultura, diretor do Butantan disse que a morte do voluntário não teve relação com o teste. A Agência Nacional de Vigilância Sanitária (Anvisa) suspendeu temporariamente os testes em humanos da vacina CoronaVac contra a Covid-19. De acordo com a agência, a interrupção foi determinada nesta segunda-feira (9) por causa de um “evento adverso grave”, mas não deu detalhes sobre a causa específica da suspensão. A Anvisa informou que foi notificada do “evento” em 29 de outubro. Mais de 10 dias depois, determinou que nenhum novo voluntário poderá ser vacinado até que a agência possa avaliar os dados e “julgar o risco/benefício da continuidade do estudo”. Segundo uma lista divulgada pela agência, são considerados eventos adversos graves “morte, evento adverso potencialmente fatal, incapacidade ou invalidez persistente, internação hospitalar do paciente, anomalia congênita ou defeito de nascimento, qualquer suspeita de transmissão ...
- Source: drugdu
- 393
- November 11, 2020
Covid-19 vaccine
FDA warns of COVID-19 antigen test false positives as report flags Quidel on accuracy

FDA has issued an alert to clinical labs and healthcare providers about the potential for COVID-19 antigen tests to deliver false positives after receiving reports from nursing homes and other settings. The agency’s Tuesday notice reminds users to follow the instructions, noting that improper storage and reading the results at the wrong time can lead to false results. At the same time, the agency said false positives could be an inevitable consequence of using tests with specificities below 100%. If a test with 98% specificity is used to screen a population in which 10% of people are infected, two out of every 10 positive results will be false. The FDA’s warning comes a day after The New York Times reported on a University of Arizona study raising concerns about the ability of a Quidel rapid antigen test to detect asymptomatic cases. The study found Quidel’s test produced more false positives than positives confirmed by the gold standard PCR tests. The potential for antigen tests ...
- Source: drugdu
- 384
- November 9, 2020
Covid-19
COVID-19 lockdowns increase the number of polio cases in Pakistan

A spike in the number of polio cases in Pakistan — the last refuge of the virus in the world along with neighbouring Afghanistan — is being attributed by health experts to disruption in vaccination services caused by lockdowns and restrictions against spread of the COVID-19 pandemic. “The increase in polio cases could result in the global export of infections and healthcare authorities must intensify efforts to track and vaccinate unvaccinated children, says Misbahud Din, researcher in molecular biology and immunology at Quaid-i-Azam University, Islamabad and lead author of a study, published October online in Public Health, on polio vaccination disruptions due to COVID-19 in Pakistan. Din tells SciDev.Net that “80 cases of wild polio virus (WPV) and 64 cases of circulating vaccine-derived poliovirus (cVDPV) have been reported in 2020”. According to the study, around 40 million children missed polio vaccination after Pakistan, on 26 March, suspended a mass vaccination programme being carried ...
- Source: drugdu
- 218
- November 8, 2020
Covid-19
Rapid rise in CRP levels predicts COVID-19 outcomes

Predicting the course of a COVID-19 patient’s disease after hospital admission is essential to improving treatment. Brigham and Women’s Hospital researchers analyzed patients’ levels of inflammation, known to be associated with severity of illness, by looking at C-reactive protein (CRP) trends in 100 COVID-19 patients admitted to the hospital. They found that a rapid rise in CRP levels during the first 48-to-72 hours of hospitalization was predictive of subsequent respiratory deterioration and intubation, while steadier CRP levels were observed in patients whose condition remained stable. Findings were published in Cell Reports Medicine. We realized that whereas a single CRP lab value from hospital admission wasn’t very practical as a predictor of who might get sicker, tracking the rate of change from Day 1 to Day 2 or 3 was a very powerful and very clinically predictive test. Even though all of these patients looked clinically similar upon admission, as early as ...
- Source: drugdu
- 344
- November 7, 2020
Covid
Fujifilm acquisition of Hitachi diagnostic imaging business delayed by COVID-19

Fujifilm Corporation’s planned $1.63 billion acquisition of Hitachi’s diagnostic imaging business has been put on hold in the midst of the ongoing COVID-19 pandemic. The Japanese healthcare giants, which began discussing the deal back in December, were aiming to complete the acquisition some time in July. Fujifilm, however, now says that “delays in some of the preparations” brought on by the spread of the virus have changed the completion schedule and that both parties will need more time to hammer out and finalize the details. “Due to the spread of CIVD19 globally, preparations for regulatory laws related to matters and clearance for anti-monopoly have been delayed. Government offices, legal offices and others impacted by lock downs and stay at home measures have slowed these activities,” Dave Wilson, director of communications for Hitachi Healthcare Americas, told HCB News. Fujifilm has delayed a planned acquisition of Hitachi’s diagnostic imaging-related business due to the ...
- Source: drugdu
- 303
- November 6, 2020
Covid-19
Argentina agrees to buy 25 million doses of Russia’s Covid-19 vaccine

President Fernández reveals in interview with Russian news agency that government will receive initial 10 million doses of Sputnik V vaccine by as early as December, should it clear clinical trials. resident Alberto Fernández said Monday that Argentina has accepted a proposal from Russia to buy an initial 10 million doses of its experimental Covid-19 vaccine, with delivery expected before the end of the year. The vaccine, which is given in two parts, could even arrive as early as next month provided clinical trials are successful, the president said in an interview with a Russian news agency. If successful, another 15 million doses could arrive in January, he added. The news comes just days after Perfil journalist Rosario Ayerdi revealed that Health Access Secretary Carla Vizzotti had travelled to Russia on October 17 on a fact-finding mission to learn more about the Russian vaccine, known as Sputnik V. Fernández confirmed Vizzotti’s ...
- Source: drugdu
- 290
- November 5, 2020
Covid-19 vaccine

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