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Genentech Announces Positive Results for First Global Phase III Study Investigating One-dose XOFLUZA (Baloxavir Marboxil) in Children With the Flu

– The MINISTONE-2 study showed XOFLUZA, given as a new oral suspension, is a well-tolerated and effective potential treatment for the flu in otherwise healthy children aged one to less than 12 years – – Approximately one in three children develop the flu every year and they are often contagious longer than adults – treating children may therefore help reduce symptoms and prevent the spread of the flu to the wider community – SOUTH SAN FRANCISCO, Calif.–(BUSINESS WIRE)–Jul. 3, 2019– Genentech, a member of the Roche Group (SIX: RO, ROG; OTCQX: RHHBY), today announced that the Phase III MINISTONE-2 study met its primary endpoint, demonstrating that XOFLUZA™ (baloxavir marboxil) was well-tolerated in children with the flu. The study also showed that XOFLUZA is comparable to oseltamivir – a proven effective treatment for children with the flu – at reducing the duration of flu symptoms, including fever. The study assessed XOFLUZA versus ...
- Source: drugdu
- 1,368
- August 2, 2019
flu Roche Xofluza
Proof-of-concept system uses smart speakers to catch signs of cardiac arrest

Author: Dave Muoio In an effort to tackle in-home cardiac arrest, University of Washington researchers have devised a novel contactless system that uses smartphones or voice-based personal assistants to identify telltale breathing patterns that accompany an attack. The proof-of-concept strategy, described in an NPJ Digital Medicine paper published this morning, involved a supervised machine learning model called a support-vector machine that was trained for use in the bedroom, a controlled environment in which the majority of in-home cardiac arrests occur. “Sometimes reported as ‘gasping’ breaths, agonal respirations may hold potential as an audible diagnostic biomarker, particularly in unwitnessed cardiac arrests that occur in a private residence, the location of [two-thirds] of all [out-of-hospital cardiac arrests],” the researchers wrote. “The widespread adoption of smartphones and smart speakers (projected to be in 75% of US households by 2020) presents a unique opportunity to identify this audible biomarker and connect unwitnessed ...
- Source: drugdu
- 907
- July 8, 2019
algorithm cardiac arrest contactless monitoring heart attack passive monitoring remote monitoring University of Washington
How Central, East Africa’s tech renaissance is shaping its healthcare future

Link：https://www.mobihealthnews.com/content/how-central-east-africas-tech-renaissance-shaping-its-healthcare-future
- Source: drugdu
- 920
- June 4, 2019
Africa EHRs healthcare
WiFi may interact with signaling pathways in the brain, causing irreversible damage

A recent study reviewed evidence from 23 controlled scientific studies which investigated the health effects of WiFi on animals, human cell lines, and humans to determine once and for all, whether WiFi has a detrimental effect on human health.
- Source: https://www.news-medical.net/news/20190418/WiFi-may-interact-with-signaling-pathways-in-the-brain-causing-irreversible-damage.aspx
- 612
- May 20, 2019
brain exposure WiFi
World Immunization Week 2019

Theme: #VaccinesWork World Immunization Week – celebrated in the last week of April – aims to promote the use of vaccines to protect people of all ages against disease. Immunization saves millions of lives every year and is widely recognized as one of the world’s most successful and cost-effective health interventions. Yet, there are still nearly 20 million unvaccinated and under-vaccinated children in the world today. The theme this year is Protected Together: Vaccines Work!, and the campaign will celebrate Vaccine Heroes from around the world – from parents and community members to health workers and innovators – who help ensure we are all protected through the power of vaccines. Vast progress but fragile gains In 2017, the number of children immunized – 116.2 million – was the highest ever reported. Since 2010, 113 countries have introduced new vaccines, and more than 20 million additional children have been vaccinated. But despite gains, all ...
- Source: drugdu
- 1,142
- May 16, 2019
health vaccine WHO
Protein C Deficiency

One of the main functions of protein C is to prevent blood clotting by inactivating proteins that encourage blood clotting. Deficiencies in protein C are associated with higher risks of developing blood clots known as deep vein thrombosis.
- Source: https://www.news-medical.net/health/Protein-C-Deficiency.aspx
- 526
- May 3, 2019
blood clots Deficiency Protein C
Individuals with infection history have higher risk of developing Sjögren’s syndrome

Environmental triggers of the immune system play an important role in the development of Sjögren's syndrome.
- Source: https://newsroom.wiley.com/press-release/journal-internal-medicine/infections-linked-increased-risk-developing-sjoegrens-syndro
- 569
- April 12, 2019
immune system Sjögren's syndrome
Could a Third Person Be Cured of HIV?

A U.K. man may be cured of HIV comes the announcement that a man in Germany may also be HIV-free thanks to a similar treatment
- Source: https://www.livescience.com/64938-hiv-cure-third-patient.html
- 638
- March 29, 2019
bone marrow genetic mutation. HIV
If You Don’t Have This Gene, You May Recover Better from a Stroke

People without a certain gene may recover better from strokes and other traumatic brain injuries than people with the gene, a new study suggests.
- Source: https://www.livescience.com/64837-ccr5-absent-stroke-recovery.html
- 355
- March 15, 2019
CCR5 CRISPR stroke
Measles Outbreak Spurs Vaccination Surge in Anti-Vaxxer Hotspot

Weeks after a hotspot for anti-vaxxers turned into a hotspot for measles infections, vaccination rates have surged in the area
- Source: https://www.livescience.com/64728-measles-outbreak-spurs-vaccination.html
- 655
- February 28, 2019
measles vaccination

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