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Neurons’ sugar coating is essential for long-term memories

How the brain is able to store memories over long periods of time has been a persistent mystery to neuroscientists. In a new study, researchers from the Centre for Integrative Neuroplasticity (CINPLA) at the University of Oslo show that long-lived extracellular matrix molecules called perineuronal nets are essential for distant memories.
- Source: medicalxpress
- 417
- December 28, 2017
memory nerve cell Researches
Study explores impact of obesity on bone marrow cells

New research published in the Journal of Experimental Medicine highlights the pernicious effect of obesity on the long-term health of blood-making stem cells (hematopoietic stem cells).
- Source: medicalxpress
- 527
- December 28, 2017
hematopoietic stem cells obesity Researches
Roche snags another Perjeta combo nod, but will ‘weak’ data limit its use?

Analysts and investors think Perjeta’s end-of-the-year indication may not be as lucrative as they once hoped. The FDA green-lighted the drug in tandem with giant Herceptin and chemo for HER2-positive, post-surgery breast cancer patients with a high risk of recurrence. Patients should receive up to 18 cycles of the regimen over the course of one year, according to the indication.
- Source: fiercepharma
- 567
- December 28, 2017
breast cancer Company Insight FDA HER2-positive
Mallinckrodt inks $1.2B Sucampo buy, ending rough 2017 on a high note

Mallinckrodt, which has landed in hot water multiple times this year, is diversifying beyond its controversial lead seller.
- Source: fiercepharma
- 446
- December 28, 2017
chronic Company Insight constipation Market Views
Baby born with bubble boy disease has no immune system and must live in total isolation

A 10-month-old boy born without an immune system has been confined to his sanitized home his entire life and only leaves for doctor's visits. Sebastian Romero was diagnosed with severe combined immunodeficiency (SCID) at two weeks old, a rare genetic disorder known as 'bubble boy' disease that left him with no infection-fighting cells.
- Source: dailymail
- 569
- December 28, 2017
bubble boy immune Researches SCID
Using CRISPR to prevent hearing loss

About half of all cases of deafness are caused by genetic defects. So it’s no surprise that the emerging gene-editing technique CRISPR-Cas9 is being examined closely for its potential to prevent hearing loss in people who inherit those genes. Scientists at the Howard Hughes Medical Institute are among those looking to deploy CRISPR in genetic deafness—and they have their first evidence that their technique may hold promise.
- Source: fiercebiotech
- 443
- December 28, 2017
CRISPR-Cas9 deafness Researches
Marital status could affect heart patients’ risk of death

New US research has found that being married may have a protective effect for patients who have suspected or confirmed heart disease, with those who are unmarried, divorced, or widowed all at a higher risk of death than married patients.
- Source: msn
- 457
- December 27, 2017
heart disease Researches
Short-term exposure to low levels of air pollution linked with premature death among US seniors

Short-term exposures to fine particulate air pollution and ozone—even at levels well below current national safety standards—were linked to higher risk of premature death among the elderly in the U.S. according to a new study from Harvard T.H. Chan School of Public Health.
- Source: medicalxpress
- 410
- December 27, 2017
premature death Researches
Researchers find potential path to repair multiple sclerosis-damaged nerves

Gene expression in specific cells and in specific regions can provide a more precise, neuroprotective approach than traditional treatments for neurological diseases. For multiple sclerosis, specifically, increasing cholesterol synthesis gene expression in astrocytes of the spinal cord can be a pathway to repair nerves that affect walking.
- Source: medicalxpress
- 466
- December 27, 2017
multiple sclerosis neurological Researches
Can’t Stop Gaming? The WHO May Soon Consider Video Game Addiction a Mental Disorder

Video game addicts of the world: Your compulsion may be considered an official mental disorder. The World Health Organization (WHO) is preparing to include it its new global medical coding guidelines.
- Source: Fortune
- 383
- December 27, 2017
mental disorder Researches

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