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4.9 billion, Siemens Healthineers makes big moves

Recently, Siemens Healthineers and the Canadian government announced a major collaboration, signing a cooperation agreement with a total investment of over 4.9 billion RMB. This new ‘value partnership’ is jointly established with the Alberta Cancer Foundation, aiming to improve healthcare service efficiency through technological innovation. Collaboration worth 4.9 billion yuan The western region of Canada is facing dual challenges of population growth and aging, with the number of cancer cases constantly increasing. To address this situation, the Alberta government will invest 800 million Canadian dollars (approximately 4.03 billion RMB) over the next eight years to fully support early detection of cancer, reduce patient waiting times, and strive to establish Alberta’s leadership position in cancer research and innovation. Siemens Healthineers will comprehensively replace outdated imaging and tumor treatment equipment throughout Alberta, while introducing innovative technologies and consulting services as solutions. This measure will significantly improve the level of medical facilities in ...
- Source: drugdu
- 54
- March 31, 2025
Maiwei Biopharma and Junshi Biopharma signed supplementary terms of the cooperation agreement on adalimumab injection

On March 27, Maiwei Biopharma (688062) issued an announcement that on March 26, 2025, the company and its wholly-owned subsidiaries signed a supplementary agreement on the cooperative development agreement on adalimumab injection with Junshi Biopharma and its wholly-owned subsidiaries. Specifically, the company is responsible for the promotion of Junmaikang® and enjoys domestic sales rights at 60% of the net sales and shipment revenue, while Junshi Biopharma is responsible for production and enjoys 40% of the rights. In addition, the two parties share domestic R&D expenses and international sales rights at a ratio of 50%:50%. In the first three quarters of 2024, Maiwei Biopharma achieved revenue of 141 million yuan and a net profit attributable to the parent of -694 million yuan. https://finance.eastmoney.com/a/202503273358105290.html
- Source: drugdu
- 54
- March 31, 2025
Alphamab Oncology’s counterattack

On March 25, Corning Jeol released its 2024 annual performance announcement, delivering an impressive report card: full-year revenue soared to 640 million yuan, a year-on-year increase of 192%, and achieved a net profit of 166 million yuan, successfully turning losses into profits. Successfully turned losses into profits According to Corning Ong’s financial report, total revenue in 2024 reached 640 million yuan, nearly double the 219 million yuan in 2023. Among them, licensing fee income performed particularly well, soaring from 7 million yuan in 2023 to 464 million yuan, becoming the main driving force for revenue growth. However, sales and royalty revenue of KN035 (Envolimab) decreased to 159 million yuan, reaching 196 million yuan in 2023. In terms of profit, the company successfully turned losses into profits, recording a net profit of 166 million yuan for the year, which was a milestone breakthrough compared to a loss of 210 million yuan ...
- Source: drugdu
- 51
- March 31, 2025
Domestic PD-L1 goes overseas again

On March 24, CStone Pharmaceuticals announced that it had submitted a new indication application for Sugemalimab to the European Medicines Agency (EMA) for the treatment of patients with stage III non-small cell lung cancer. If approved, CStone Pharmaceuticals will further consolidate its position in the field of lung cancer immunotherapy. Rolling towards Europe Sugemalimab is a fully human, full-length anti-PD-L1 monoclonal antibody developed by CStone Pharmaceuticals. According to a press release from CStone Pharmaceuticals, the drug is a natural G-type immunoglobulin 4 (IgG4) monoclonal antibody drug that is closest to the human body. It can reduce the potential risk of immunogenicity and related toxicity in patients. Compared with similar drugs, Sugemalimab will have unique advantages. The drug was first approved for marketing in China in December 2021 for the first-line treatment of non-small cell lung cancer combined with chemotherapy. It has since been approved for multiple indications including lung cancer, ...
- Source: drugdu
- 49
- March 31, 2025
Big news! A new premature ejaculation drug that works in one spray is launched, and Fosun Pharma enters the billion-dollar market

On March 24, the official website of the Center for Drug Evaluation (CDE) of the China National Medical Products Administration showed that the application for the listing of the 5.1 new drug lidocaine prilocaine aerosol jointly submitted by Plethora Solutions and Fosun Pharma was officially accepted. The drug’s trade name is Fortacin, which has been on the market in the EU for more than ten years and has been converted to OTC. If lidocaine prilocaine aerosol is approved, it will fill the gap in the field of premature ejaculation treatment in China, which has long relied on the oral drug dapoxetine, and provide patients with a new option of “one spray and immediate effect”. Premature ejaculation is one of the most common sexual dysfunctions in men, with an incidence rate of 2.3% among urban men in China. Currently, the only drug approved for the treatment of PE in China is ...
- Source: drugdu
- 40
- March 31, 2025
【EXPERT Q&A】What is Antibody-polypeptide Conjugate (APC)?

Drugdu.com expert’s response: Antibody-Peptide Conjugate (APC) is a specialized biopharmaceutical that links an antibody with a peptide through specific chemical bonds. This conjugate combines the targeting properties of the antibody with the biological activity of the peptide, enabling precise treatment of specific cells or tissues. Below is a detailed explanation of Antibody-Peptide Conjugate (APC): I. Definition and Structure Antibody-Peptide Conjugate (APC) is a complex formed by chemically linking an antibody and a peptide. The antibody is responsible for recognizing and binding to specific antigens on target cells or tissues, while the peptide carries therapeutically active molecules or groups. This structure allows APC to precisely target diseased sites while releasing therapeutic peptides, achieving localized high-concentration drug treatment. II. Preparation and Application Preparation Method: Antibody Reduction: Firstly, the interchain disulfide bonds of the antibody are reduced to produce thiol groups, providing active sites for subsequent conjugation reactions. Peptide Conjugation: Then, the chemically modified ...
- Source: drugdu
- 49
- March 31, 2025
14.5 billion yuan! Novo Nordisk authorizes domestic GLP-1/GIP/GCG agonists

Recently, Federal Biotech, a wholly-owned subsidiary of Federal Pharmaceuticals (03933. HK), reached an exclusive licensing agreement with multinational pharmaceutical giant Novo Nordisk for up to $2 billion (approximately RMB 14.5 billion, calculated at the latest exchange rate of 1 USD ≈ 7.2579 RMB). According to the agreement, Novo Nordisk will obtain the exclusive right to develop, produce and commercialize a weight loss drug UBT251 in the world outside Chinese Mainland, Hong Kong, Macao and Taiwan. Union Bio will receive a down payment of $200 million, a potential milestone payment of up to $1.8 billion, and a graded royalty based on net sales in Chinese Mainland, Hong Kong, Macao and Taiwan. UBT251 is a GLP-1 (glucagon like peptide-1)/GIP (glucose dependent insulinotropic polypeptide)/GCG (glucagon) triple target receptor agonist currently in early clinical development and has shown effective activity against all three receptors in preclinical settings. At present, UBT251 has been approved in ...
- Source: drugdu
- 56
- March 28, 2025
1 Medical Device Approved by FDA

Recently, the US Food and Drug Administration (FDA) approved for the first time a system for cleaning complex internal channels of flexible endoscopes, which are stubborn sources of hospital acquired infections. This breakthrough was achieved by Nanosonics’ automated CORIS equipment. It is reported that Nanosonics’ CORIS device is specifically designed for stubborn biofilms formed in the narrowest areas of endoscopy. In the conventional reprocessing process, these areas cannot be touched by manual brushing. The residue composed of patient cells may gradually develop resistance to high-level disinfectants during multiple cleaning cycles. This Australian company pointed out that research on gastroscopy and colonoscopy has found biofilm residues in the microchannels of all devices, and some outbreaks of hospital acquired infections can be traced back to specific antibiotic resistant strains carried inside these reusable instruments. Previously, the FDA has urged medical technology developers and healthcare institutions to switch to endoscopic systems that contain ...
- Source: drugdu
- 57
- March 28, 2025
$18.5 billion in unfinished orders in 2024, convertible into $3.7 billion within three years

WuXi Biologics (02269), the world’s leading biopharmaceutical CDMO, handed in its 2024 report. The 2024 financial report shows that the company achieved annual revenue of 18.675 billion yuan, a year-on-year increase of 9.6%; net profit of 3.945 billion yuan, a year-on-year increase of 10.5%. After excluding COVID-19-related revenue, WuXi Biologics’ non-COVID-19 business achieved a year-on-year growth of 13.1%, showing the resilience of its fundamentals. It is worth noting that preclinical research service revenue increased by 30.7% year-on-year, accounting for 37.8% of total revenue, becoming the main force driving growth. In terms of regional revenue, North American market revenue increased by 32.5% year-on-year, contributing 57.3% of total revenue. But the other side of the coin is that the revenue in China fell by 9.6%, exposing the continued impact of the cold winter of local biotech financing. In 2024, WuXi Biologics’ gross profit margin increased by 0.9 percentage points year-on-year to 41%, ...
- Source: drugdu
- 58
- March 28, 2025
CanSino Biologics lost 379 million yuan last year and made a profit only one year after its listing

On the evening of March 25, CanSino Biologics released its 2024 annual report. The company achieved operating income of 846 million yuan for the whole year, an increase of 137.01% year-on-year; the net loss attributable to the parent company’s owners was 379 million yuan, and the loss narrowed by 74.45% year-on-year. Since its listing, CanSino Biologics, which has been losing money continuously, turned losses into profits in 2021 with the help of the new crown vaccine. As the competition for the new crown vaccine intensified and demand slowed down, it fell into losses again in the second year. Until 2024, CanSino Biologics has been losing money for three consecutive years. Increase in revenue from meningococcal vaccines The operating income in 2024 increased significantly, mainly due to the impact of the estimated return of the new crown vaccine in the same period of 2023, which reduced the operating income by 253 ...
- Source: drugdu
- 54
- March 28, 2025

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