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Chinese Scientists Achieve Functional Cure for Type 1 Diabetes Using Stem Cell Regeneration Therapy

Chinese scientists have made a breakthrough in the treatment of major diseases using induced pluripotent stem cells, achieving the first functional cure for Type 1 diabetes through stem cell regeneration therapy. The research team, composed of the groups led by Shen Zhongyang and Wang Shusen from Tianjin First Central Hospital, Deng Hongkuai from Peking University and Changping Laboratory, and Zhejiang Ruipu Chenchuang Technology Co., Ltd., utilized chemical reprogramming techniques to induce pluripotent stem cells to create insulin-producing beta cells. These cells were then transplanted into a Type 1 diabetes patient, resulting in a clinically functional cure. The findings were published on the evening of September 25 in the international prestigious journal — Cell. https://finance.eastmoney.com/a/202409263191732155.html
- Source: drugdu
- 125
- September 27, 2024
Jacobs’ Pan-KRAS inhibitor approved for clinical trial in the US

September 23, 2024 – The clinical trial application (IND) for Pan-KRAS inhibitor JAB-23E73 independently developed by JACOBIO was approved in the United States, and a Phase I/IIa clinical trial for advanced solid tumors will be conducted in the United States. The IND application for China has been submitted, and clinical trials will be conducted in China simultaneously after approval. KRAS is widely present in a variety of tumor mutations. 23%-25% of cancer patients have KRAS mutations. About 2.7 million new tumor patients with KRAS-related mutations each year are expected to benefit from Pan-KRAS inhibitors. JAB-23E73 can inhibit both active and inactive KRAS, and has no significant inhibition on HRAS and NRAS. As an oral KRAS inhibitor, JAB-23E73’s preclinical data showed good pharmacokinetic properties. JACOBIO is committed to providing patients with breakthrough treatment options. The company’s research projects are based on the six major tumor signaling pathways of KRAS, tumor immunity, ...
- Source: drugdu
- 97
- September 27, 2024
The CSRC encourages cross-border mergers and acquisitions of unprofitable assets, a new path for Biotech to enter the capital market?

On September 24, Wu Qing, chairman of the CSRC, said at a press conference of the State Council that in order to further stimulate the vitality of the merger and reorganization market, the CSRC has studied and formulated the “Opinions on Deepening the Reform of the Merger and Reorganization Market of Listed Companies” (“Six Mergers and Acquisitions”, hereinafter referred to as the “Opinions”), including supporting listed companies to transform and upgrade to new quality productivity, encouraging industrial integration, improving regulatory tolerance, and improving the transaction efficiency of the reorganization market. Among them, it is clearly stated that listed companies are strongly supported to carry out cross-industry mergers and acquisitions and acquisitions of unprofitable assets based on transformation and upgrading. This means that unprofitable biotech companies may usher in a new path to enter the capital market. At the meeting, Wu Qing said that mergers and acquisitions are major events in ...
- Source: drugdu
- 145
- September 27, 2024
【EXPERT Q&A】What is the difference between medical devices and non-medical devices?

Drugdu.com expert’s response: The differences between medical devices and non-medical devices are primarily manifested in the following six aspects: Ⅰ. Definition and Purpose Medical Devices: Refer to instruments, equipment, appliances, in vitro diagnostic reagents and calibrators, materials, and other similar or related articles, including the necessary computer software, that are directly or indirectly used on the human body. Their efficacy is primarily obtained through physical means rather than through pharmacology, immunology, or metabolism, or if these means are involved, they only play an auxiliary role. The primary purposes include diagnosis, prevention, monitoring, treatment, or alleviation of diseases, as well as diagnosis, monitoring, treatment, alleviation, or functional compensation of injuries. Non-Medical Devices: Generally refer to products that are not directly used on the human body or, even if in contact with the human body, do not have a medical purpose. They may be daily necessities, industrial products, consumer goods, such as ...
- Source: drugdu
- 95
- September 27, 2024
2 injections for 1 year, a preview of conquering AIDS

Since June 2024, all scholars around the world who care about AIDS prevention have focused their attention on Gilead’s antiviral drug lenacapavir. At that time, Gilead announced the latest data of the PURPOSE 1 trial conducted by lenacapavir, and the results showed that: in the case of head-to-head daily oral PrEP drugs, lenacapavir achieved 0 infection with 2 injections per year. This means that in the case of unfavorable vaccine development, lenacapavir is expected to replace the preventive effect of the vaccine with its ultra-persistent prevention characteristics. Of course, is the result of the PURPOSE1 trial accidental or inevitable? No one can give an answer. But in September, Gilead continued to provide PURPOSE 2 trial data, indicating to the outside world that the possibility of inevitability is greater. The results showed that 99.9% of the participants in the Lenacapavir group were not infected with HIV, and the risk of infection ...
- Source: drugdu
- 87
- September 27, 2024
Bausch&Lomb is in a crisis of being sold

Recently, according to the Financial Times, Bausch Lomb, the world’s second-largest ophthalmic giant, is seeking to sell itself and completely spin off from its parent company, Bausch Health. In recent years, under the implementation of merger and acquisition strategies, Doctoral Health has developed its business pipeline comprehensively. However, due to being trapped in a huge debt crisis, it had to reduce its burden and slim down. Bausch&Lomb is one of the targets of its sale and spin off this time. Mergers and acquisitions are both successful and unsuccessful Bausch&Lomb was founded in New York, USA in 1853 and was listed on both the New York Stock Exchange and the Toronto Stock Exchange in 2022. It has a development history of nearly 170 years. At first, Bausch&Lomb was just a small eyewear store, but over the years, it has become one of the world-renowned eye care companies. From the perspective of ...
- Source: drugdu
- 95
- September 26, 2024
How to layout after recall and reorganization? Philips CEO responds

Recently, Roy Jakobs, CEO of Philips, gave an interview to foreign media and responded to questions such as how to reverse the company’s situation after a large-scale recall and the company’s restructuring plan. According to data, Philips was founded in the Netherlands in 1891 and mainly produces products in lighting, household appliances, and medical systems. The company has transformed from a Philips family business to a global multinational corporation managed by modern professional managers. In its 130 year history, it has evolved from a lighting business to a diversified enterprise that covers almost everything, and then continuously “slimmed down”. Eventually, it sold off its lighting business, leaving only medical care. It has successfully transformed from an electronics group into a global top medical technology giant, leading in the fields of imaging diagnosis, image-guided therapy, patient monitoring, health informatization, consumer health, and home care. In October 2022, Roy Jakobs became the ...
- Source: drugdu
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- September 26, 2024
CMEH

Organiser：China Healthcare Industry Association, Chinese Medical Exchange Association Time：June 25 – 27, 2025 address：No. 1099 Guozhan Road or No. 111 Shiboguan Road, Pudong New Area, Shanghai, China Exhibition hall：Shanghai World Expo Exhibition & Convention Center Product range: Medical Imaging: CT, DR, Medical X-ray Systems, Ultrasound Diagnostic Instruments, MRI Equipment, Tumor Treatment Machines, Medical Film and Processing Systems, etc.; Remote & Mobile Intelligent Medical Monitoring: Sleep Monitors, Remote ECG, Blood Pressure, Blood Oxygen, Body Temperature Monitoring, Cloud Blood Pressure Monitors, Bluetooth Blood Pressure & Blood Glucose Monitors, Wearable Medical Devices, Health Kiosks, etc.; Diagnostic & Therapeutic Equipment: Endoscopy Systems, ENT Treatment Instruments, Dynamic Analysis Instruments, Cryogenic Freezing Equipment, Dialysis Treatment Equipment, Emergency Equipment, Surgical Instruments, Electrosurgical Units & Consumables, Laser Surgical Instruments, Ultrasound Surgery, etc.; Ward Nursing Equipment & Appliances: Beds, Trolleys, Tables, Cabinets, Racks, etc.; Disinfection Products: Medical Air Sterilizers, Vacuum Sterilizers, Ultrasonic Cleaning Systems, Disinfectants/Solutions, etc.; Auxiliary Products: ...
- Source: drugdu
- 246
- September 26, 2024
Ocuvision nails first generic anti-allergic eye drop

Last week (September 9 to September 15), a total of 58 varieties passed/were deemed to have passed the consistency evaluation. During the same period, 123 varieties applied for consistency evaluation. According to the official website of NMPA, Suzhou Ocuvision Biotechnology Co., Ltd. (hereinafter referred to as “Ocuvision”)’s cetirizine hydrochloride eye drops obtained a marketing approval on September 10. The drug is indicated for the treatment of itchy eyes associated with allergic conjunctivitis and is suitable for people aged 2 years and above. Allergic conjunctivitis is an allergic disease of the eye that occurs more frequently in spring and autumn. The disease is mainly manifested by itchy eyes, accompanied by red and swollen eyelids, congestion and edema of the conjunctiva (white eyeballs), increased tears or white secretions, and some patients also have symptoms such as nasal congestion, itchy nose, clear runny nose, and sneezing. Cetirizine hydrochloride eye drops are one of ...
- Source: drugdu
- 96
- September 26, 2024
Major Pharmaceutical Holdings’ Subsidiary for Traditional Chinese Medicine Officially Starts Production

On September 24, reporters from Dahe Finance learned through Major Pharmaceutical Holdings’ official WeChat account that recently, the opening ceremony for Chongqing Pharmaceutical Group Jiulong Modern Traditional Chinese Medicine Co., Ltd. (hereinafter referred to as “Zhongyao Jiulong”) was held in Nanchuan District, Chongqing City. Officials from relevant departments, including the Chongqing Economic and Information Commission, the Health Commission, and the Drug Administration, as well as leaders from the Nanchuan District Committee and District Government, attended the ceremony. Noteworthy attendees included Qiu Huaiwei, Secretary of the Party Committee and Chairman of China Resources Sanjiu Medical & Pharmaceutical Co., Ltd. (hereinafter referred to as “China Resources Sanjiu”), and Yuan Quan, Secretary of the Party Committee and Chairman of Chongqing Pharmaceutical (Group) Co., Ltd. (hereinafter referred to as “Zhongyao Group”). Zhongyao Jiulong was established in October 2020 through joint investment from Major Pharmaceutical Holdings’ subsidiary, Zhongyao Group, and China Resources Sanjiu. The company ...
- Source: drugdu
- 83
- September 26, 2024

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