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FIME 2023

FIME is the largest medical specialty show in the southeastern United States. The feature of the exhibition is both regional and international. In addition to exhibitors and professional buyers mainly from Florida, the exhibition has attracted a large number of exhibitors and professional buyers from Latin American countries by taking advantage of the advantageous geographical location of the exhibition city adjacent to the Caribbean Sea. A large number of products and equipment are re-exported to Caribbean countries and markets through Florida.
- Source: drugdu
- 747
- June 1, 2023
Cats can play a role in transmitting COVID-19, finds new study

Cats can play a role in the transmission of SARS-CoV-2 and their contaminated environment (pens in this study) can be infectious, according to new research. The study is published in Microbiology Spectrum. “In practice, after the introduction of SARS-CoV-2 in our household, we should see our cat as part of the family regarding virus transmission,” said study co-author Wim van der Poel DVM, Ph.D., Professor of Emerging and Zoonotic Viruses, Wageningen University and Research, in the Netherlands. Dr. van der Poel and colleagues conducted the study to gain better insight into the risk of COVID-19 infection that could arise from cats infected with SARS-CoV-2. In the study, 16 cats were either directly exposed to SARS-CoV-2 virus obtained from a naturally infected human patient, exposed indirectly from a directly exposed cat, or exposed from the pen in which an infected cat was housed. All cats were regularly sampled during the whole ...
- Source: drugdu
- 133
- June 1, 2023
More depressed patients than previously estimated could have increased activation of their immune system

New research from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King’s College London has used an assessment of gene expression involved in the immune response to show that there could be more patients with major depressive disorder (MDD) with activated immune systems than research has previously estimated. By identifying the molecular mechanisms involved in this association, the research could pave the way to better identify those patients with an immune component to their depression which would potentially help to provide more personalized approaches to treatment and management of MDD. The research, published in Translational Psychiatry builds on previous findings that there is an activated immune response in many people with MDD. However, most of the research in this area has focused on the levels of inflammation related proteins like C-reactive protein (CRP). Studies using CRP have found that about 21 to 27 % of people with depression have ...
- Source: drugdu
- 118
- June 1, 2023
Cortisol levels in late pregnancy can predict sleep health of infants

Cortisol levels in late pregnancy can predict the sleep of infants, according to a new study to be presented at the SLEEP 2023 annual meeting. Results show that newborns with higher levels of cortisol in their hair samples took longer to fall asleep at 7 months of age. Neonatal hair cortisol is a measure of fetal cortisol in the last trimester of pregnancy. Melissa Nevarez-Brewster (lead co-author, graduate student, University of Denver) said, “Although increases in cortisol across pregnancy are normal and important for preparing the fetus for birth, our findings suggest that higher cortisol levels during late pregnancy could predict the infant having trouble falling asleep. We are excited to conduct future studies to better understand this link.” The researchers collected hair cortisol from 70 infants in the first days after birth; 57% of the infants were female. Parents then completed a sleep questionnaire when their child was 7 ...
- Source: drugdu
- 107
- June 1, 2023
Alnylam sticks with aggressive litigation strategy against Pfizer and Moderna, filing yet another patent lawsuit

Alnylam Pharmaceuticals isn’t letting up with its COVID-19 vaccine patent allegations. Late last week, the company filed its third set of lawsuits against the two largest manufacturers of coronavirus vaccines. Once again, RNA specialist Alnylam is accusing Pfizer and Moderna of violating its lipid particle delivery technology with their lucrative COVID-19 vaccines. Specifically, Alnylam claims that Pfizer stepped on four of its patents and that Moderna infringed three. With the lawsuits, it’s seeking a “reasonable royalty” for the alleged damages. The new suits come after Alnylam originally sued the two last March, arguing that it invented the delivery tech utilized by the vaccines more than a decade ago. Then, in July, the biotech followed up with new claims. Earlier this month, Moderna hit back against the claims in a set of countersuits, alleging that Alnylam “baselessly seeks to profit” from its inventions. Moderna pointed out that the company “based its ...
- Source: drugdu
- 116
- June 1, 2023
After price cuts, Eli Lilly inks $13.5M settlement in long-running insulin lawsuit

Eli Lilly has agreed to pay $13.5 million to end a six-year, class-action lawsuit that alleged the company overpriced its insulin. As part of the settlement, which was recorded (PDF) in a federal district court in New Jersey, Lilly has agreed to cap out-of-pocket costs for its insulin at $35 per month for four years. The deal comes three months after the company said it would slash price of the type 1 diabetes treatment to the same level to “make it easier to access Lilly insulin and help Americans who may have difficulty navigating a complex healthcare system.” Lilly’s initial move had come a month after President Joe Biden, in his State of the Union address, called on Congress to limit insulin costs for all patients to $35 per month. The Inflation Reduction Act already had limited insulin costs for patients on Medicare at $35 per month. The lawsuit was ...
- Source: drugdu
- 117
- June 1, 2023
【EXPERT Q&A】How to ace the process of drug registration?

Drugdu.com expert’s response: Drug registration is a complex task that involves multiple steps. To do it well, you need to follow these steps: 1. Understand regulations and guidelines: Firstly, understand the related laws, guidelines, and policies of drug registration to ensure your product complies with the requirements of the country or region where it’s being registered. These laws and guidelines usually cover requirements for drug quality, safety, and efficacy. 2. Prepare registration materials: Prepare relevant registration materials according to the drug registration requirements of the country or region. These materials usually include the chemical, biological, and pharmacological properties of the drug, the drug development process, production technology, quality control, clinical trial data, drug labels, and instructions. Ensure the materials you submit are complete, accurate, and easy to understand. 3. Conduct clinical trials: In some cases, you may need to conduct clinical trials to prove the safety and effectiveness of the ...
- Source: drugdu
- 230
- May 31, 2023
【EXPERT Q&A】How to improve the response rate of emails for international trade development?

Drugdu.com expert’s response: Email marketing, as one of the essential tools for medical trade marketing, can significantly influence customer responses and even determine the success of your orders. Therefore, editing emails requires attention to detail and technique, as a small detail might prompt a customer to reply to your email. So, how can you write high-response-rate emails that make customers eager to reply? Deduo Medical Trade Network shares four essential email editing tips: Five times more people read email subject lines than the email body Readers usually judge whether to continue reading an email based on the subject line’s appeal, especially for customers who receive many emails every day. If your email subject line can grab the customer’s attention, you are already halfway successful. To increase the chances of customers opening your email, consider these three subject line patterns (use with caution as they may risk being marked as spam): 1.Imitate ...
- Source: drugdu
- 275
- May 31, 2023
【EXPERT Q&A】What exactly is the difference between intermediates and active pharmaceutical ingredients?

Drugdu.com expert’s response: Both intermediates and active pharmaceutical ingredients (APIs) are chemical substances used in the pharmaceutical manufacturing process, but they serve different roles and purposes. An API refers to a chemical substance used to manufacture pharmaceutical products, typically obtained through chemical synthesis or natural extraction. APIs are the foundation of pharmaceutical manufacturing and are a crucial factor in determining the quality and efficacy of the drugs. APIs usually have specified chemical structures and purity requirements, therefore, the quality control and standard requirements for APIs are relatively high. Intermediates, on the other hand, are chemical substances used in the synthesis of APIs during the pharmaceutical manufacturing process. They are typically intermediate products obtained through multiple chemical reaction steps. Although intermediates themselves usually do not possess pharmacological activity, they play a significant role in pharmaceutical manufacturing, influencing the synthesis efficiency, quality, and cost of APIs, among other factors. Intermediates generally need ...
- Source: drugdu
- 281
- May 31, 2023
Study maps immune responses produced by COVID-19 vaccination in First Nations population

Published in Nature Immunology and Nature Briefing, the research is the first of its kind to decisively map immune responses produced by a COVID-19 vaccination in any First Nations populations. In partnership with Menzies School of Health Research, researchers at the Peter Doherty Institute for Infection and Immunity (Doherty Institute) evaluated immune responses in Aboriginal and Torres Strait Islander peoples and non-Indigenous individuals after receiving the mRNA COVID-19 vaccine. Lead author of the study and PhD candidate at the Doherty Institute, University of Melbourne’s Wuji Zhang, said the research provides strong evidence that COVID-19 vaccination triggers effective immune responses against the virus in First Nations peoples. “We found excellent antibody and T cell responses against SARS-CoV-2 in Australian First Nations peoples following COVID-19 vaccination. We saw high levels of antibodies binding to the virus following two vaccine doses,” Mr Zhang said. “T cells against the spike protein, which often recognize ...
- Source: drugdu
- 116
- May 31, 2023

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