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Fate of 1,000 trafficked lab monkeys at center of US investigation in limbo

‘Long-tailed macaques at risk of being killed, or laundered or re-trafficked if returned to Cambodia, animal welfare groups say’ More than a thousand Cambodian monkeys at the center of a US government investigation into wildlife trafficking are at risk of being killed or returned to their country of origin, laundered and re-trafficked, animal welfare groups say. The monkeys’ plight first came to light last year when the US Fish and Wildlife Service (FWS) asked the animal rights organization Peta about finding a sanctuary for 360 monkeys. Born Free USA, and the US Department of Justice (DoJ) later joined the discussions and the number of monkeys increased to over 1,000 as talks progressed. Last week, however, discussions stalled when Peta learned on 13 March that the monkeys would instead be flown out of the US. Under US law the monkeys can only return to their country of origin, Cambodia, said Dr Lisa Jones-Engel of Peta, ...
- Source: drugdu
- 179
- March 21, 2023
New Drug Combination Shows Promise in Treating Lung Cancer

Researchers from the University of Texas MD Anderson Cancer Center have found that a combination of two drugs may be effective in treating non-small cell lung cancer (NSCLC). NSCLC is the most common type of lung cancer and accounts for approximately 85% of all lung cancer cases. The study, published in the journal Nature Medicine, involved analyzing data from over 1,000 patients with NSCLC. The researchers identified a group of genes that were associated with resistance to immunotherapy, a type of cancer treatment that uses the body’s immune system to fight cancer cells. The researchers then tested a combination of two drugs, a checkpoint inhibitor and a targeted therapy, in mouse models of NSCLC. The checkpoint inhibitor works by releasing the brakes on the immune system, allowing it to attack cancer cells. The targeted therapy works by inhibiting a protein that is overexpressed in many types of cancer ...
- Source: drugdu
- 127
- March 21, 2023
Virtual Reality Therapy Shows Promise in Treating PTSD

A new study has found that virtual reality therapy may be an effective treatment for post-traumatic stress disorder (PTSD). PTSD is a mental health condition that can develop after experiencing or witnessing a traumatic event, such as military combat, sexual assault, or a natural disaster. Symptoms of PTSD can include flashbacks, nightmares, and anxiety. The study, published in The Lancet Psychiatry, involved 103 military veterans with PTSD. The veterans were randomly assigned to receive either virtual reality therapy or traditional therapy, which involved talk therapy and other forms of therapy. The virtual reality therapy involved wearing a headset that displayed virtual environments related to the veterans’ traumatic experiences. The veterans were able to interact with the virtual environments and practice coping strategies to manage their symptoms. The researchers found that the veterans who received virtual reality therapy had greater reductions in PTSD symptoms than those who received ...
- Source: drugdu
- 125
- March 21, 2023
Gene Editing May Hold the Key to Curing Sickle Cell Disease

Researchers from the University of California, Berkeley have used CRISPR gene-editing technology to cure sickle cell disease in mice. Sickle cell disease is a genetic blood disorder that affects millions of people worldwide. The disease is caused by a mutation in the HBB gene, which produces an abnormal form of hemoglobin that causes red blood cells to become misshapen and break down easily. Using CRISPR, the researchers were able to correct the HBB gene in mice with sickle cell disease. The corrected gene produced normal hemoglobin, which prevented the misshapen red blood cells from forming. The mice were cured of the disease and showed no signs of sickle cell-related symptoms. The researchers say that the same approach could be used to cure sickle cell disease in humans. While more research is needed before clinical trials can begin, this is a promising development in the field of gene therapy. ...
- Source: drugdu
- 127
- March 21, 2023
Scientists Develop New Blood Test for Detecting Alzheimer’s Disease

Researchers at Washington University School of Medicine in St. Louis have developed a new blood test that can detect Alzheimer’s disease in its early stages. The test looks for a specific protein called tau, which is known to be a key biomarker of Alzheimer’s. Currently, the most common way to diagnose Alzheimer’s disease is through cognitive testing and brain imaging scans. However, these methods can be costly and invasive. Additionally, by the time symptoms appear, the disease has already caused significant damage to the brain. The new blood test offers a non-invasive and potentially more accessible way to diagnose Alzheimer’s disease early on, when treatments may be more effective. The study, published in the journal Nature Medicine, involved analyzing blood samples from 158 individuals, including healthy adults, individuals with mild cognitive impairment, and individuals with Alzheimer’s disease. The researchers used a technique called mass spectrometry to measure levels ...
- Source: drugdu
- 138
- March 21, 2023
Big news! Hengrui ADC innovative drug SHR-A1811 new indication to be included in breakthrough therapy species

Recently, Hengrui Medicine’s ADC innovative drug SHR-A1811 for the treatment of HER2-mutated advanced non-small cell lung cancer who failed previous platinum-based chemotherapy was proposed to be included in the public list of breakthrough therapy varieties by the Center for Drug Evaluation of the National Medical Products Administration. The study was led by Professor Lu Shun from the Chest Hospital Affiliated to Shanghai Jiaotong University, and a total of 10 centers across the country participated. At the same time, the other two indications of SHR-A1811 have been included in the list of breakthrough therapy varieties by the Drug Evaluation Center of the State Drug Administration in February this year. The indications are: low expression of human epidermal growth factor receptor 2 (HER2). Recurrent or metastatic breast cancer and human epidermal growth factor receptor 2 (HER2) positive recurrent or metastatic breast cancer. Lung cancer is currently the leading cause of cancer-related death ...
- Source: drugdu
- 143
- March 20, 2023
The high price of Ozempic is pushing many to unregulated, copycat drugs for weight loss

Some compounding pharmacies are offering what they say are generic versions of the drugs, which have soared in popularity for weight loss. When Robin Langois, 58, was prescribed the weight-loss drug Wegovy last year, she couldn’t afford the high price tag after her insurance wouldn’t cover it. But she later discovered on TikTok that people could get their hands on what appeared to be the drug’s active ingredient, semaglutide, from compounding pharmacies for a fraction of the price. Langois, of Tucson, Arizona, said she was initially hesitant, because of safety concerns, but she eventually found a telehealth provider to write her a prescription. “I’m not 100% sure it’s what I’m getting,” Langois said. She noted, however, that she’s experienced feelings of fullness and weight loss, as well as nausea, a common side effect of the drug. “It’s working like it should,” she said. Either due to cost or ongoing shortages, ...
- Source: drugdu
- 168
- March 20, 2023
UBS buys Credit Suisse for $3.2 billion as regulators look to shore up the global banking system

The Financial Times reported that UBS has agreed to buy the bank for more than $2 billion, a substantial increase from the initial $1 billion offer it reported earlier Sunday. UBS agreed to buy its embattled rival Credit Suisse for $3.2 billion Sunday, with Swiss regulators playing a key part in the deal as governments looked to stem a contagion threatening the global banking system. “With the takeover of Credit Suisse by UBS, a solution has been found to secure financial stability and protect the Swiss economy in this exceptional situation,” read a statement from the Swiss National Bank, which noted the central bank worked with the Swiss government and the Swiss Financial Market Supervisory Authority to bring about the combination of the country’s two largest banks. The terms of the deal will see Credit Suisse shareholders receive 1 UBS share for every 22.48 Credit Suisse shares they hold. “This ...
- Source: drugdu
- 196
- March 20, 2023
Organoid Intelligence

Researchers just announced a plan to eventually create “organoid intelligence,” or OI. They plan to grow clumps of brain cells called organoids and create technology that would allow us to turn those clumps of cells into powerful and efficient computers. The technology is only in its infancy, but it has implications for everything from computer memory to neurological diagnostics. The human brain is a wonderful and complicated organ. Despite decades of study and scientific progress, there’s still a lot we don’t know about how it works and why it behaves the way it does. But we know it’s powerful. It might not be as quick to solve complex equations as a computer, but it’s wildly more energy-efficient and significantly better at both learning and memory. And recently, researchers have been looking into how combine a brain and a computer, giving us the power of a human mind at our fingertips. ...
- Source: drugdu
- 128
- March 20, 2023
New Study Shows Promising Results for Targeted Cancer Therapy

A recent study published in the Journal of Clinical Oncology has shown promising results for a new type of cancer therapy. The therapy, known as a targeted therapy, uses drugs that specifically target the genetic mutations that drive the growth of cancer cells. Traditional cancer treatments like chemotherapy and radiation therapy are often associated with serious side effects because they damage healthy cells along with cancer cells. Targeted therapies, on the other hand, are designed to be more precise and have fewer side effects. The new study focused on a targeted therapy called larotrectinib, which is designed to treat cancers that have a specific genetic mutation called NTRK fusion. NTRK fusion is a rare but important genetic alteration that is found in a variety of cancers, including certain types of lung, colon, and breast cancer. The study included 55 patients with NTRK fusion-positive cancer who were treated with larotrectinib. The ...
- Source: drugdu
- 177
- March 20, 2023

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