Search Results for “AI” – Page 19 – media

Chiatai Tianqing Enrolls Subjects in a Clinical Study of TQB2223 Injection in Combination with Paanoprilumab for the Treatment of Lymphoma, Lung Cancer and Nasopharyngeal Carcinoma

Chiatai Tianqing Pharmaceutical Group Co., Ltd. is conducting a nationwide Phase I clinical trial to evaluate the tolerability and pharmacokinetics of TQB2223 Injection in combination with Paanoprilumab in subjects with advanced malignant tumors. The study has been approved by the State Drug Administration (Notification No. 2023LP00274) and passed the center’s ethics, and is now recruiting nationwide. Trial drug profile TQB2223 injection is a lymphocyte activation gene-3 monoclonal antibody (LAG-3), registered as therapeutic biological product class 1. LAG-3, as an immune checkpoint, is expressed in activated T cells, NK cells, B cells and plasmacytoid dendritic cells, etc., and can negatively regulate T cells, which plays an important role in the maintenance of homeostasis of the body’s immune system and the promotion of tumor immune escape. LAG-3 monoclonal antibody can block the LAG-3 ligand on the cell surface, enhance the secretion of cytokines and exert anti-tumor immunity. Pavelizumab is a PD-1 monoclonal ...
- Source: drugdu
- 90
- May 15, 2024
NHS still faces waiting list challenges

Commenting on the publication today of the NHS monthly performance statistics, Tim Gardner, Assistant Director of Policy at the Health Foundation, said: ‘While the pressure of winter has eased, today’s data shows urgent and emergency care is still feeling the strain. Over 42,000 patients spent more than 12 hours in A&E before being admitted to a bed last month, and 1 in 10 with a serious condition such as a stroke or chest pain waited over an hour for an ambulance. ‘There are some positive signs in areas of cancer care but following several months of progress, the overall waiting list in March 2024 has remained broadly flat. Fewer than expected referrals into specialist care means the recent fall in the waiting list was largely driven by fewer patients joining the list, rather than because substantially more are being treated. The reality is the waiting list is still 7.5 million, ...
- Source: drugdu
- 143
- May 14, 2024
OneChain’s CAR T trial treats its first cortical T-cell ALL patient

The subtype accounts for 20% of all T-cell leukaemias, a rare form of blood cancer which produces too many abnormal T-cells OneChain Immunotherapeutics (OCI), a biotechnology company that specialises in developing CAR T cell therapies for oncological diseases, has announced that the CARxALL clinical trial has dosed its first cortical T-cell acute lymphoblastic leukaemia (coT-ALL) patient with OC-1, a CAR T therapy. Being conducted at Hospital Clínic and Hospital Sant Joan de Déu in Barcelona, the trial is open to both paediatric and adult patients worldwide. T-cell leukaemia is a rare form of blood cancer that occurs when the bone marrow produces too many abnormal T-cells, a type of white blood cell that protects the body from infections. The subtype, coT-ALL, accounts for 20% of T-cell leukaemias and is characterised by a poor prognosis in patients who do not respond to existing therapies. CAR T therapies are a form of ...
- Source: drugdu
- 117
- May 13, 2024
Chiatai Tianqing Completes Enrollment of First Subject in Phase III Clinical Trial of New Class 1 Drug Garsorasib (D-1553)

Chiatai Tianqing is conducting the “Randomized, controlled, double-blind, dual-simulation, multicenter Phase III clinical study to evaluate D1553 versus docetaxel for the treatment of locally advanced or metastatic non-small cell lung cancer with KRAS G12C mutation-positive lung cancer that has failed previous standard therapy (D1553-III-01)” nationwide. Recently, the project has completed the enrollment and successful dosing of the first subject. Garsorasib is a novel targeted KRAS G12C mutation inhibitor, registered under the classification of chemical drug class 1, is the first self-developed KRAS G12C inhibitor in China that has entered the clinical trial stage, and is included in the breakthrough therapeutic varieties by the CDE. on December 29, 2023, the National Drug Administration (NMPA) has accepted Garsorasib’s New Drug Marketing Application for the treatment of locally advanced or metastatic non-small cell lung cancer with disease progression or intolerable disease after prior first-line systemic therapy and with the presence of a KRAS ...
- Source: drugdu
- 81
- May 10, 2024
Cipla and Glenmark initiate recall of certain products in the US

Cipla and Glenmark Pharmaceuticals are recalling specific products from the US market due to distinct manufacturing issues, the latest Enforcement Report issued by the US Food and Drug Administration (USFDA) noted. The recalls involve inhalation solutions and extended-release capsules used for treating respiratory conditions and high blood pressure, respectively. New Jersey-based subsidiary of Cipla, Cipla USA is recalling 59,244 packs of Ipratropium Bromide and Albuterol Sulfate Inhalation Solution. This product is manufactured at Indore SEZ plant of the company in India. It is prescribed for controlling the symptoms of lung diseases such as chronic bronchitis, asthma, and emphysema. The recall of the affected inhalation solution lot is claimed to be due to complaints of “short fill”. The US regulator detailed that the affected lot was recalled after reports of less fill volume in respules and the presence of a few drops of liquid in the intact pouch. Simultaneously, Glenmark Pharmaceuticals, ...
- Source: drugdu
- 125
- May 8, 2024
Cambridge researchers use AI to accelerate drug design for Parkinson’s disease

The progressive neurological condition affects more than six million people worldwide Researchers from the University of Cambridge have designed and used an artificial-intelligence (AI)-based approach to advance drug design and accelerate the search for Parkinson’s disease (PD) treatments. Published in the journal Nature Chemical, researchers used AI to identify compounds that block the clumping or aggregation of alpha-synuclein, the key protein that characterises PD. Affecting more than six million people worldwide, PD is a progressive neurological condition that slowly deteriorates parts of the brain. As well as motor symptoms, PD can also affect the gastrointestinal system, nervous system, sleeping patterns, mood and cognition and can contribute to a reduced quality of life and significant disability. Researchers developed and used a machine learning technique to screen a chemical library that contained millions of entries to identify small molecules that bind to the amyloid aggregates and block their proliferation. The process of ...
- Source: drugdu
- 150
- May 6, 2024
Research Shows Generative AI In The EHR Can Work Well, But Only With Human Oversight

As the burden of documentation and various other administrative duties has increased, physician burnout has reached historical levels. In response, EHR vendors are embedding generative AI tools to aid physicians by drafting their responses to patient messages. However, there is a lot that we don’t yet know about these tools’ accuracy and effectiveness. Researchers at Mass General Brigham recently conducted research to learn more about how these generative AI solutions are performing. They published a study last week in The Lancet Digital Health showing that these AI tools can be effective at reducing physicians’ workloads and improving patient education — but also that these tools have limitations that require human oversight. For the study, the researchers used OpenAI’s GPT-4 large language model to produce 100 different hypothetical questions from patients with cancer. The researchers had GPT-4 answer these questions, as well as six radiation oncologists who responded manually. Then, the ...
- Source: drugdu
- 103
- May 6, 2024
UK sets out position on regulating AI as a medical device

Dive Brief A U.K. agency outlined its position on the regulation of artificial intelligence as a medical device in a policy paper published Tuesday.The Medicines and Healthcare products Regulatory Agency (MHRA) said many AI products that can be put on the market now without conformity assessment will move to a higher risk category in upcoming reforms.The paper explains how MHRA interprets a government AI strategy focused on principles such as safety, security and robustness and aligns it with international standards. Dive Insight The U.K. government committed to five cross-sector principles for the regulation of AI in February. A consultation found “strong support” for the principles, the government said, and established them as the basis for a regulatory framework designed to keep pace with rapidly advancing AI technology. Days later, the government wrote to the MHRA to request details of its approach to AI. In response, the MHRA published a policy ...
- Source: drugdu
- 111
- May 5, 2024
Patient Rights Advocate Files Amicus Brief in Lawsuit Against Blue Cross Blue Shield of Minnesota

The fight over affordable drug prices continues. PatientRightsAdvocate.org announced that it has filed an amicus brief in the Department of Labor’s (DOL) case against Blue Cross Blue Shield of Minnesota.1 Acting secretary of labor Julie A. Su filed the case in January of this year, claiming that Blue Cross collected about $66.8 million for provider taxes from 370 self-funded employer health plans. Provider taxes vary from state to state, but they are typically paid by hospitals and clinics. These funds can be used as a source of funding for Medicaid, provided they meet certain requirements. In the lawsuit,2 the DOL of writes, “BCBSM, Inc. has for years unilaterally caused the self-funded health benefit plans for which it serves as third-party administrator to compensate BCBSM, Inc.’s in-network providers for amounts they owe under a Minnesota provider tax—amounts the providers never billed or passed on to the plans—without authority to do so under the ...
- Source: drugdu
- 117
- May 5, 2024
“Profound concern” over WHO’s pandemic agreement, says AIDS charity

The AHF Global Public Health Institute has voiced concerns over the World Health Organization’s (WHO) proposed pandemic agreement, saying that the private interest of pharmaceutical companies has taken priority over global health security. The AHF Global Public Health Institute, a joint initiative of the AIDS Healthcare Foundation and the University of Miami, outlined issues in the latest iteration of the text from the WHO via a 26 April press release. The Pandemic Agreement, also known as the pandemic accord, is a proposed international joint initiative to fight the next pathogen that threatens global health. The framework is meant to implement lessons learned from the response to Covid-19 to improve shared response between nations. Member states have a deadline of May 2024 to join the treaty accord. Research indicates that Covid-19 would have caused 40 million more deaths in the absence of preventative measures. Countries have been ...
- Source: https://www.pharmaceutical-technology.com/news/profound-concern-over-whos-pandemic-agreement-says-aids-charity/?cf-view
- 136
- May 4, 2024

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