Spain’s annual life expectancy at birth dropped by 0.9 years between 2019 and the annual period up until July 2020 due to the COVID-19 pandemic, according to a new study published this week in the open-access journal PLOS ONE by Sergi Trias-Llimos of the Center for Demographic Studies, Spain, and colleagues. The COVID-19 pandemic is causing substantial increases in mortality in populations worldwide, and Spain was one of the most affected countries in the spring of 2020. Life expectancy is an easy to interpret, standard indicator in mortality patterns. However, few studies assessing the impact of the pandemic on mortality to date have reported life expectancy estimates. In the new study, researchers used daily death count data from the Spanish Daily Mortality Monitoring System (MoMo) as well as information on death, population and demographic information from the Spanish National Statistics Institute. The team estimated weekly and annual life expectancies at birth for ...
Monday, November 09, 2020 – 06:45am Vaccine candidate was found to be more than 90% effective in preventing COVID-19 in participants without evidence of prior SARS-CoV-2 infection in the first interim efficacy analysis Analysis evaluated 94 confirmed cases of COVID-19 in trial participants Study enrolled 43,538 participants, with 42% having diverse backgrounds, and no serious safety concerns have been observed; Safety and additional efficacy data continue to be collected Submission for Emergency Use Authorization (EUA) to the U.S. Food and Drug Administration (FDA) planned for soon after the required safety milestone is achieved, which is currently expected to occur in the third week of November Clinical trial to continue through to final analysis at 164 confirmed cases in order to collect further data and characterize the vaccine candidate’s performance against other study endpoints This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20201109005539/en/ NEW YORK & MAINZ, GERMANY–(BUSINESS WIRE)– Pfizer Inc. (NYSE: ...
By Maggie Fox, CNN Updated 5:36 PM ET, Thu October 22, 2020 (CNN) The US Food and Drug Administration has approved remdesivir for the treatment of coronavirus infection, the drug’s maker, Gilead Sciences, said Thursday. It is the first drug to be approved for treating Covid-19. The drug, sold under the brand name Veklury, has been used under emergency use authorization since May. The antiviral has shown, at best, a modest benefit for coronavirus patients. But there is little else available. “In the United States, Veklury is indicated for adults and pediatric patients (12 years of age and older and weighing at least 40 kg) for the treatment of COVID-19 requiring hospitalization,” the company said in a statement. “Veklury should only be administered in a hospital or in a healthcare setting capable of providing acute care comparable to inpatient hospital care.” Earlier this month, a World Health Organization-sponsored global study found remdesivir ...
Last month, Russia announced the approval of a COVID-19 vaccine called Sputnik V. This week, President Vladimir Putin announced the approval of a second vaccine, called EpiVacCorona. As with the first, scientists have not yet tested this vaccine in phase 3 trials. The vaccine was developed by scientists at the State Virology and Biotechnology Center, known as Vektor, in Novosibirsk. According to The Moscow Times: “Early trials on 100 volunteers were said to have been successful.” In a televised news conference, Putin explained that researchers had given the vaccine to Deputy Prime Minister Tatyana Golikova and the head of Russia’s consumer safety watchdog, Anna Popova, as part of ongoing trials. During the briefing, they explained that: “Early trials on 100 volunteers were said to have been successful.” As with Sputnik V, experts are likely to view the new vaccine with skepticism. Vaccines must be rigorously investigated before they can be used widely, and ...
By HospiMedica International staff writers Posted on 14 Oct 2020 Image: Colorized scanning electron micrograph of a cell (purple) heavily infected with SARS-CoV-2 virus particles (yellow) (Photo courtesy of National Institute of Allergy and Infectious Diseases, National Institutes of Health) A recent study has shown that blocking a specific protein in a biological pathway may prevent SARS-CoV-2 infection and keep the virus from misdirecting the immune system against healthy cells and organs. While the world waits eagerly for a safe and effective vaccine to prevent infections from SARS-CoV-2, the virus behind the COVID-19 pandemic, researchers also are focusing on better understanding how SARS-CoV-2 attacks the body in the search for other means of stopping its devastating impact. The key to one possibility – blocking a protein that enables the virus to turn the immune system against healthy cells – has been identified in a recent study by ...
By HospiMedica International staff writers Posted on 08 Sep 2020 Researchers from the University of Oxford (Oxford, UK) have found that natural infection with COVID-19 produces a robust T cell response, including inducing T cell ‘memory’ to potentially fight future infections. While research has shown that COVID-19 induces a B cell antibody response, it has been less clear whether COVID-19 causes the immune system to make virus-specific T cells too, and whether they are important for recovery from the initial infection, and protection against new infections. While antibodies latch onto and destroy disease-causing agents like viruses and bacteria, T cells latch on to diseased cells within the body, such as tumor cells or virus-infected cells. T-cells also help attract other immune cells to the area. T cells are attracted to tumor or viral protein fragments (called epitopes) displayed on the surface of diseased cells, which act like waving a flag ...
A study by the Oxford University’s Centre for Evidence-Based Medicine (Oxford, England) suggests that the current COVID-19 diagnostic tests could be too sensitive and may be detecting dead coronavirus cells, leading to overestimated infections. According to the researchers, the tests used to diagnose COVID-19 are so sensitive that they may be indicating people are infected with SARS-CoV-2 even when they had the virus 70 days ago. Prof Carl Heneghan, director of the Centre for Evidence-Based Medicine, believes that eight days after contracting COVID-19, the chances of an infected person passing on the virus to others become zero if there are no symptoms. However, fragments of the coronavirus can still remain in the body for several weeks afterwards. Polymerase chain reaction (PCR) tests currently used to detect SARS-CoV-2 have technical limitations as they cannot distinguish whether the virus in the patient is alive or dead. The researchers analyzed 25 studies on ...
By HospiMedica International staff writers Posted on 31 Aug 2020 A drug used to cure a deadly disease caused by a coronavirus in cats is expected to prove equally effective as a treatment for humans against COVID-19. Researchers at the University of Alberta (Edmonton, Alberta, Canada) are now preparing to launch clinical trials of the drug which is a protease inhibitor that interferes with the virus’s ability to replicate, thus ending an infection. Proteases are key to many body functions and are common targets for drugs to treat everything from high blood pressure to cancer and HIV. First studied by the University of Alberta researchers following the 2003 outbreak of severe acute respiratory syndrome (SARS), the protease inhibitor was further developed by veterinary researchers who showed it cures a disease that is fatal in cats. The team synthesized the compounds and tested them against the SARS-CoV-2 virus in test ...
Nov.19 2019 source: https://www.medicalnewstoday.com/articles/326967.php#1 Medical News Today Previously, scientists have linked the presence of human papillomavirus to an increased risk of certain cancers. In a surprising twist, the latest research finds that the virus might help defend against skin cancer. There are more than 100Trusted Source strains of human papillomavirus (HPV), only a handful of which experts consider to be a risk to human health. Scientists have linked these strains with an increased risk of certain cancers, including those of the cervix, vulva, penis, and anus. Of the remaining strains of HPV, many are little more than harmless stowaways on our skin. These so-called commensal viruses are the subject of scrutiny for a group of researchers at Massachusetts General Hospital in Boston. The scientists recently published a paper in NatureTrusted Source, which concludes that immunity to these HPV strains may protect against skin cancer.
Source : Medical News Today https://www.medicalnewstoday.com/articles Previously, scientists have linked the presence of human papillomavirus to an increased risk of certain cancers. In a surprising twist, the latest research finds that the virus might help defend against skin cancer. There are more than 100Trusted Source strains of human papillomavirus (HPV), only a handful of which experts consider to be a risk to human health.Scientists have linked these strains with an increased risk of certain cancers, including those of the cervix, vulva, penis, and anus.Of the remaining strains of HPV, many are little more than harmless stowaways on our skin.These so-called commensal viruses are the subject of scrutiny for a group of researchers at Massachusetts General Hospital in Boston.The scientists recently published a paper in NatureTrusted Source, which concludes that immunity to these HPV strains may protect against skin cancer.
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