Search Results for “EC” – Page 113 – media

New machine-learning method predicts body clock timing to improve sleep and health decisions

A new machine-learning method could help us gauge the time of our internal body clock, helping us all make better health decisions, including when and how long to sleep. The research, which has been conducted by the University of Surrey and the University of Groningen, used a machine learning program to analyze metabolites in blood to predict the time of our internal circadian timing system. The study is published in the journal Proceedings of the National Academy of Sciences. To date the standard method to determine the timing of the circadian system is to measure the timing of our natural melatonin rhythm, specifically when we start producing melatonin, known as dim light melatonin onset (DLMO). Professor Debra Skene, co-author of the study from the University of Surrey, said, “After taking two blood samples from our participants, our method was able to predict the DLMO of individuals with an accuracy comparable ...
- Source: drugdu
- 120
- April 26, 2023
Proper nutrition could boost recovery from traumatic brain injury

In the first few days after a traumatic brain injury (TBI), food is often an afterthought as clinicians focus on minimizing the damage to the brain. However, a new study suggests that getting enough calories can help boost the brain’s healing process, making nutrition an important consideration for improving TBI care. Researchers will present their work this week at the American Physiology Summit, the flagship annual meeting of the American Physiological Society (APS), in Long Beach, California. “This evidence highlights the importance of ensuring proper nutrition for TBI patients during recovery. Specifically, formulations containing fuels that are preferred by the brain, such as lactate, should be prioritized during the acute and chronic phases of recovery from TBI.” Casey C. Curl, Doctoral Candidate, Exercise Physiology Laboratory, University of California, Berkeley When a person comes to the hospital with a traumatic brain injury, many patients go for several days without ...
- Source: drugdu
- 133
- April 25, 2023
New injectable cell therapy could resolve osteoarthritis

Wake Forest Institute for Regenerative Medicine (WFIRM) scientists have created a promising injectable cell therapy to treat osteoarthritis that both reduces inflammation and also regenerates articular cartilage. Recently identified by the Food and Drug Administration as a public health crisis, osteoarthritis affects more than 520 million people worldwide who deal with pain and inflammation. Osteoarthritis is typically induced by mechanical or traumatic stress in the joint, leading to damaged cartilage that cannot be repaired naturally. “Without better understanding of what drives the initiation and progression of osteoarthritis, effective treatment has been limited,” said lead author Johanna Bolander of WFIRM. “Initially, we studied what goes wrong in osteoarthritic joints, compared these processes to functional environments, and used this information to develop an immunotherapy cell treatment.” Osteoarthritis is a disease of the joint system. The joint includes a synovial membrane—a connective tissue that lines the inner surface of the joint. The membrane functions to protect the joint ...
- Source: drugdu
- 116
- April 25, 2023
Personalized recipe of hopamine can empower patients with Parkinson’s disease

When Marina Noordegraaf was diagnosed with Parkinson’s disease at age 49, she noticed when it came to treatment decisions, she sometimes felt powerless. She observed that she herself played an active role in communicating her hopes and wishes to her healthcare professionals, which were not automatically taken into account. She took back control by taking her own hope seriously, prescribing her own recipe of “hopamine,” a self-invented word representing the uniquely personal set of hopes, desires, experiences, and skills of each individual with Parkinson’s disease, which is caused by a dopamine deficit. Marina Noordegraaf, MSc, together with a team of healthcare professionals at Radboud University Medical Centre in Nijmegen, the Netherlands, led by Professor Bastiaan R. Bloem, MD, PhD, recognized the importance of conveying the message of hopamine to the broader Parkinson’s world. In a commentary published in the Journal of Parkinson’s Disease, the authors propose that ...
- Source: drugdu
- 118
- April 24, 2023
New research reveals how coffee and tea can affect risk of early death for adults with diabetes

If you have type 2 diabetes, drinking more coffee, tea or plain water may lower your risk of dying prematurely from any cause by about 25%, a new study found. However, drinking more sugar-sweetened beverages raised the risk of heart disease by 25% and the risk of dying from a heart attack or another cardiovascular event by 29%, the study said. Research has shown cardiovascular disease is the most common cause of death for people with type 2 diabetes. “Certain beverages are absolutely more beneficial than others, depending on which type of beverage you’re comparing,” said study author Qi Sun, an associate professor of nutrition and epidemiology at the Harvard T.H. Chan School of Public Health in Boston. “Based on our study I would rank black coffee, unsweetened tea and plain water higher than low-fat milk, fruit juice or artificially sweetened beverages,” he said. “Sugar-sweetened beverages like ...
- Source: drugdu
- 124
- April 24, 2023
US Supreme Court delays abortion pill access decision

By Nadine Yousif & Robin Levinson-King BBC News The US Supreme Court has extended until Friday a temporary block on limits to access of a popular abortion pill. A Texas judge suspended approval of abortion drug mifepristone on 7 April, questioning its safety. Parts of that decision were upheld on appeal, prompting the Biden administration to make an emergency request to the Supreme Court. It’s the most significant such case since the Supreme Court last year ended the nationwide right to abortion. The pill – used in more than half of abortions in the US – was first approved by the Food and Drug Administration (FDA) more than two decades ago. Here’s how we got here. What has happened so far? Earlier this month, a federal judge in Texas issued a preliminary injunction revoking the FDA’s approval for the drug while he hears a lawsuit brought by a group of ...
- Source: drugdu
- 135
- April 24, 2023
A new mechanism for crossing the blood–brain barrier

The blood–brain barrier (BBB) is a stringent, nearly impenetrable layer of cells that guards the brain, protecting the vital organ from hazards in the bloodstream such as toxins or bacteria and allowing only a very limited set of small molecules, such as nutrients, to pass through. This layer of protection, however, makes it difficult for researchers to study the brain and to design drugs that can treat brain disorders. Now, a new study from Caltech has identified a previously unknown mechanism by which certain viral vectors—protein shells engineered to carry various desired cargo—can cross through the BBB. This mechanistic insight may provide a new approach to designing viral vectors for research and therapeutic applications. Understanding this and other new mechanisms could also give insight into how the brain’s defenses may be exploited by emergent pathogens, enabling researchers to prepare methods to block them. The research was conducted in the laboratory of ...
- Source: drugdu
- 147
- April 20, 2023
Are Electric Vehicles Safe for Pacemaker Patients?

A new study investigates the risk of electromagnetic interference with pacemakers and defibrillators when using high power electric vehicle chargers. Amanda Pedersen | Apr 19, 2023 With the increasing popularity of electric vehicles, you might be wondering if it’s safe to drive or charge one of these bad boys if you have a pacemaker or defibrillator. According to a new study, presented this week at the European Heart Rhythm Association (EHRA) in Barcelona, Spain, the answer is yes – so long as you don’t place the charging cable directly over your cardiac device, or stay near the charging cable for extended lengths of time. The study was also published in EP Europace, a journal of the European Society of Cardiology, which hosts the EHRA scientific congress. “The new high power charging stations for electric cars have the potential to create strong electromagnetic fields and cause electromagnetic interference in pacemakers and defibrillators, leading them to malfunction,” said study author ...
- Source: drugdu
- 132
- April 20, 2023
Study Suggests Increased Number of PMA Supplements Increase Recall Risk

Investigators also highlighted long-standing concerns that modified devices may bear little resemblance to the device originally FDA-approved. Katie Hobbins | Apr 19, 2023 Recently, a study published in JAMA Network Open reported that high-risk medical devices whose manufacturers file supplements to the FDA so modifications can be made to PMA-approved products are 30% more likely to be the subject of any recall and high-risk Class I recall. Makers of Class III PMA devices are offered five different types of supplements to allow for product improvements. Only one of the supplements — namely, panel track supplements — actually require clinical evidence for implementation and, as such, are the least-used type of the five, (approximately 1%). In contrast, the most used supplement type is a 30-day notice. A 30-day notice is used when a company makes changes to a manufacturing procedure or the way it makes a device. In the study, investigators analyzed devices approved through ...
- Source: drugdu
- 136
- April 20, 2023
How the brain tells the liver to start recycling after fasting

Fasting triggers autophagy in our body. The body switches on the waste disposal system in the cells and gains new energy. Researchers at the Max Planck Institute for Metabolism Research in Cologne have now shown in mice that the brain plays a decisive role in this process. Even after a short period of fasting, the brain triggers the release of the hormone corticosterone and thus initiates autophagy in the liver. Until now, it was assumed that mainly the liver cells themselves were responsible for this. In the long term, these findings could help us understand why fasting is so healthy for the body. Autophagy is essential for survival. Defective or damaged molecules are shredded and degraded by the cell’s own waste disposal system and new energy is generated from this. This kind of detoxification of the body keeps the body fit and very likely young. “Until now, it was assumed that our body cells mainly ...
- Source: drugdu
- 137
- April 19, 2023

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