On November 6, 2024, Hengrui Medicine, the “pharmaceutical leader” listed on the A-share market, announced that the second lock-up period of the company’s 2022 employee stock ownership plan will expire on November 7, 2024. After the expiration, the management committee will dispose of the rights and interests in accordance with the provisions of this employee stock ownership plan based on the arrangements of this employee stock ownership plan, market conditions and other comprehensive factors. This also means that hundreds of core employees of Hengrui Medicine will share a big “red envelope” again. Hengrui’s employee stock ownership plan was established in November 2022. The shares came from the company’s repurchase special securities account, totaling 12 million shares; according to the disclosed information at the time, the transfer price was only 4.97 yuan/share. As of November 6, 2024, Hengrui Medicine’s closing price was 48.75 yuan/share, which is nearly 10 times the original ...
The third quarter of 2024 is an epoch-making watershed. An unprecedented large-scale stagnation has occurred in the consumer healthcare field. From medical beauty, ophthalmology, dentistry, pharmaceutical retail, branded Chinese medicine, growth hormone to self-funded vaccines, the leaders in various segments have become old and collectively lost their growth potential. The mismatch between business model, product structure and consumer market is one of the reasons for the predicament, but it is so difficult for a company to get out of the path dependence that created its former glory. Now there are two problems. First, how does the market value companies that have lost their growth but are still profitable? When a company stops growing, the only investment attraction is high dividends, but consumer healthcare companies are almost all stingy. Second, when will consumption pick up? When will the consumption inflection point come? Japan’s situation from 1990 to 1997 is inspiring. Consumption ...
On the morning of November 6th, at the 7th China International Import Expo (CIIE), Jean Christophe Pointeau, President of Pfizer China, a multinational pharmaceutical giant, revealed that the company will launch the “Pfizer China 2030 Strategy” during this year’s CIIE. From 2025 to 2030, Pfizer will invest 1 billion US dollars, about 7.5 billion yuan, in China. Pfizer will continue to invest in accelerating innovation, improving diagnostic capabilities and treatment standards, and promoting the development of the local biotechnology industry to support the ‘Healthy China 2030’ initiative. This strategy is based on three pillars: firstly, accelerating the launch of innovative drugs and introducing breakthrough innovative products more quickly; The second is to continue to improve diagnostic capabilities and treatment standards, especially in rural areas, and promote the connection between first-class hospitals and rural areas; The third is to promote the development of the local biotechnology industry. As an important part ...
According to media statistics, in the first half of 2024 alone, at least 32 innovative pharmaceutical companies in China successfully completed BD projects, achieving cross-border expansion and involving transaction amounts exceeding 20 billion US dollars, with a significant increase in quantity compared to previous years. And this trend continues into the second half of the year, with domestic innovative pharmaceutical companies such as Ruige Pharmaceutical, Jiahe Biotechnology, Tongrun Biotechnology, and Anmai Biotechnology all having significant BD transactions. Recently, a domestic innovative pharmaceutical company that has only been established for eight years and currently has only a few pipelines under research sold one of its products, BD, for a sky high price. GlaxoSmithKline (GSK) has officially announced that it has reached an acquisition agreement with Chinese innovative pharmaceutical company Chimagin Biosciences for the three specific antibody CMG1A46. Accordingly, GSK will make a prepayment of $300 million to Enmu Biotechnology to acquire ...
Never underestimate the power of the tide. “AI+ empowerment” is becoming an important engine to promote the expansion of new quality productivity in various industries, and the medical and health system is no exception. For the medical and health system, improving productivity and efficiency while reducing the cost of patients and healthcare systems is an eternal topic. This also means that the greatest potential of AI+ healthcare lies not only in the application of one or two scenarios, but in assisting and optimizing medical services in all aspects, and completely rewriting the order of all links of “diagnosis and treatment”. At this year’s CIIE, through the display of Roche, the industry leader, we can see that this trend is already very obvious: AI is penetrating in multiple dimensions to meet the individualized diagnosis and treatment needs of patients and change the direction of the tide in multiple fields. Although many ...
In the past ten years, Precision Science’s colorectal cancer early screening product Cologuard has told an open growth story. The continuous growth has also made Cologuard synonymous with colon cancer screening. However, after more than ten years of growth, can Cologuard continue? There are many affirmative voices, but wavering emotions are also beginning to appear. On November 6, Precision Science handed in a good third-quarter report. In the third quarter, Precision Science’s total revenue reached US$707 million, a year-on-year increase of 13%; among them, the core screening business revenue was US$545 million, a year-on-year growth rate of 15%. Although the growth rate is still considerable, Precision Science has lowered its full-year revenue guidance. The scale of screening business revenue is US$78 million less than expected, and the full-year revenue cap of this business is US$2.095 billion. This means that there will be a decline in the fourth quarter compared with ...
Recently, the National Medical Insurance Bureau has uniformly deployed various provinces to carry out standardized governance of medical service prices, promote reasonable price reductions for some large-volume and high-priced inspection and testing items, further reduce the burden on patients to see doctors, and promote the relative balance of inspection and testing prices among provinces. Which items will be focused on? At present, there are more than 2,000 inspection and testing items in various provinces across the country. Affected by factors such as information barriers, the prices of some items vary greatly in different provinces. For example, the thromboelastogram test, which is a test used to evaluate coagulation function, costs 360 yuan per time in some places and only 100 yuan per time in some places, which is several times different. The reason behind this is mainly that the procurement costs of some inspection reagents or equipment are inflated, resulting in ...
Pancreatic cancer is known as the “king of cancer” because of its high malignancy and lack of effective drug treatment. However, the research and development community has never stopped its efforts to conquer this type of cancer. Recently, Hengrui Medicine announced that the results of the Phase III study of irinotecan liposome (II) combined with advanced pancreatic cancer were published in the Nature sub-journal “Signal Transduction and Targeted Therapy”. The results showed that the irinotecan liposome combination regimen reduced the risk of death in pancreatic cancer patients by 37% compared with the control group. In the next era beyond chemotherapy, perhaps ADC drugs will become the main force in the fight against pancreatic cancer. For example, Innovent Biologics’ ADC targeting cluadin18.2 and Lepu Bio’s ADC targeting EGFR each have their own surprises, and both have shown breakthrough efficacy in the remission rate of pancreatic cancer. In addition, Kangfang has also ...
Recently, Wellizbo announced that its independently developed and globally intellectual property-owned Class 1 new drug LBL-034 has been granted orphan drug designation by the U.S. Food and Drug Administration (FDA) for the treatment of multiple myeloma (MM). LBL-034 is a new generation of humanized bispecific T cell engaging antibodies targeting GPRC5D and CD3 developed using Wellizbo’s independently developed and intellectual property-owned CD3 bispecific antibody technology platform “LeadsBodyTM”. It is the third CD3 T cell connector targeting GPRC5D to enter the clinical stage in the world. Multiple myeloma (MM) is a malignant plasma cell disease caused by abnormal proliferation of clonal plasma cells, accounting for about 10% of hematological malignancies and about 1% of all tumor diseases. MM is still an incurable malignancy. With multiple lines of medication, the interval between relapses will become shorter and shorter, and eventually evolve into RRMM, which seriously threatens the life and health of patients. ...
Recently, the National Medical Insurance Administration has attracted attention through the verification of drug traceability codes. What is a drug traceability code? What does it mean if a drug traceability code is scanned repeatedly? What role does the drug traceability code play in ensuring the security of medical insurance funds? How to use drug traceability codes? What is a drug traceability code? Answer: The drug traceability code is the “electronic ID card” of the drug. It is usually composed of a series of numbers, letters and (or) symbols. It is marked in a prominent position on the drug packaging box. It is the unique identity label given to each box of drugs from the time of production. If the drug traceability code appears repeatedly during the circulation process, the drug may be a “returned drug”, a counterfeit drug, or sold in a scrambled manner. The drug traceability code has three ...
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