Sri Lanka has secured a $2.9bn (£2.3bn) bailout from the International Monetary Fund (IMF) as it faces its worst economic crisis since independence. The deal has been nearly a year in the making and a lifeline for the country that has billions of dollars in loans. Foreign minister Ali Sabry told the BBC the government will raise funds by restructuring state-owned enterprises and privatising the national airline. However, analysts warned Sri Lanka still faces a tough road ahead. The country’s economy has been hit hard by the pandemic, rising energy prices, populist tax cuts and inflation of more than 50%. A shortage of medicines, fuel and other essentials also helped to push the cost of living to record highs, triggering nationwide protests which overthrew the ruling government in 2022. As a result the country defaulted on its debts with international lenders last May for ...
Unhealthy food cravings in adulthood can be traced all the way back to fetal development, according to new research from Rutgers University. The study, published this week in Molecular Metabolism, shows that exposure to excess calories while in the womb can alter one’s brain and spur adult overeating. The researchers made the connection by studying 6 pregnant mice, then their combined litters of nearly 50 mice pups through adulthood. They began by letting 3 mice become obese on unlimited high-fat foods during pregnancy and breastfeeding, while keeping the other 3 pregnant mice slim from a diet of healthy food. The team found that the mice pups born to the obese mothers overate more than the mice pups born to the lean mothers when given access to unhealthy chow. The findings suggest that children who are born to mothers who were overweight during pregnancy and nursing may similarly struggle later in life to moderate ...
‘Long-tailed macaques at risk of being killed, or laundered or re-trafficked if returned to Cambodia, animal welfare groups say’ More than a thousand Cambodian monkeys at the center of a US government investigation into wildlife trafficking are at risk of being killed or returned to their country of origin, laundered and re-trafficked, animal welfare groups say. The monkeys’ plight first came to light last year when the US Fish and Wildlife Service (FWS) asked the animal rights organization Peta about finding a sanctuary for 360 monkeys. Born Free USA, and the US Department of Justice (DoJ) later joined the discussions and the number of monkeys increased to over 1,000 as talks progressed. Last week, however, discussions stalled when Peta learned on 13 March that the monkeys would instead be flown out of the US. Under US law the monkeys can only return to their country of origin, Cambodia, said Dr Lisa Jones-Engel of Peta, ...
Researchers from the University of Texas MD Anderson Cancer Center have found that a combination of two drugs may be effective in treating non-small cell lung cancer (NSCLC). NSCLC is the most common type of lung cancer and accounts for approximately 85% of all lung cancer cases. The study, published in the journal Nature Medicine, involved analyzing data from over 1,000 patients with NSCLC. The researchers identified a group of genes that were associated with resistance to immunotherapy, a type of cancer treatment that uses the body’s immune system to fight cancer cells. The researchers then tested a combination of two drugs, a checkpoint inhibitor and a targeted therapy, in mouse models of NSCLC. The checkpoint inhibitor works by releasing the brakes on the immune system, allowing it to attack cancer cells. The targeted therapy works by inhibiting a protein that is overexpressed in many types of cancer ...
A new study has found that virtual reality therapy may be an effective treatment for post-traumatic stress disorder (PTSD). PTSD is a mental health condition that can develop after experiencing or witnessing a traumatic event, such as military combat, sexual assault, or a natural disaster. Symptoms of PTSD can include flashbacks, nightmares, and anxiety. The study, published in The Lancet Psychiatry, involved 103 military veterans with PTSD. The veterans were randomly assigned to receive either virtual reality therapy or traditional therapy, which involved talk therapy and other forms of therapy. The virtual reality therapy involved wearing a headset that displayed virtual environments related to the veterans’ traumatic experiences. The veterans were able to interact with the virtual environments and practice coping strategies to manage their symptoms. The researchers found that the veterans who received virtual reality therapy had greater reductions in PTSD symptoms than those who received ...
Researchers from the University of California, Berkeley have used CRISPR gene-editing technology to cure sickle cell disease in mice. Sickle cell disease is a genetic blood disorder that affects millions of people worldwide. The disease is caused by a mutation in the HBB gene, which produces an abnormal form of hemoglobin that causes red blood cells to become misshapen and break down easily. Using CRISPR, the researchers were able to correct the HBB gene in mice with sickle cell disease. The corrected gene produced normal hemoglobin, which prevented the misshapen red blood cells from forming. The mice were cured of the disease and showed no signs of sickle cell-related symptoms. The researchers say that the same approach could be used to cure sickle cell disease in humans. While more research is needed before clinical trials can begin, this is a promising development in the field of gene therapy. ...
Researchers at Washington University School of Medicine in St. Louis have developed a new blood test that can detect Alzheimer’s disease in its early stages. The test looks for a specific protein called tau, which is known to be a key biomarker of Alzheimer’s. Currently, the most common way to diagnose Alzheimer’s disease is through cognitive testing and brain imaging scans. However, these methods can be costly and invasive. Additionally, by the time symptoms appear, the disease has already caused significant damage to the brain. The new blood test offers a non-invasive and potentially more accessible way to diagnose Alzheimer’s disease early on, when treatments may be more effective. The study, published in the journal Nature Medicine, involved analyzing blood samples from 158 individuals, including healthy adults, individuals with mild cognitive impairment, and individuals with Alzheimer’s disease. The researchers used a technique called mass spectrometry to measure levels ...
Recently, Hengrui Medicine’s ADC innovative drug SHR-A1811 for the treatment of HER2-mutated advanced non-small cell lung cancer who failed previous platinum-based chemotherapy was proposed to be included in the public list of breakthrough therapy varieties by the Center for Drug Evaluation of the National Medical Products Administration. The study was led by Professor Lu Shun from the Chest Hospital Affiliated to Shanghai Jiaotong University, and a total of 10 centers across the country participated. At the same time, the other two indications of SHR-A1811 have been included in the list of breakthrough therapy varieties by the Drug Evaluation Center of the State Drug Administration in February this year. The indications are: low expression of human epidermal growth factor receptor 2 (HER2). Recurrent or metastatic breast cancer and human epidermal growth factor receptor 2 (HER2) positive recurrent or metastatic breast cancer. Lung cancer is currently the leading cause of cancer-related death ...
Some compounding pharmacies are offering what they say are generic versions of the drugs, which have soared in popularity for weight loss. When Robin Langois, 58, was prescribed the weight-loss drug Wegovy last year, she couldn’t afford the high price tag after her insurance wouldn’t cover it. But she later discovered on TikTok that people could get their hands on what appeared to be the drug’s active ingredient, semaglutide, from compounding pharmacies for a fraction of the price. Langois, of Tucson, Arizona, said she was initially hesitant, because of safety concerns, but she eventually found a telehealth provider to write her a prescription. “I’m not 100% sure it’s what I’m getting,” Langois said. She noted, however, that she’s experienced feelings of fullness and weight loss, as well as nausea, a common side effect of the drug. “It’s working like it should,” she said. Either due to cost or ongoing shortages, ...
The Financial Times reported that UBS has agreed to buy the bank for more than $2 billion, a substantial increase from the initial $1 billion offer it reported earlier Sunday. UBS agreed to buy its embattled rival Credit Suisse for $3.2 billion Sunday, with Swiss regulators playing a key part in the deal as governments looked to stem a contagion threatening the global banking system. “With the takeover of Credit Suisse by UBS, a solution has been found to secure financial stability and protect the Swiss economy in this exceptional situation,” read a statement from the Swiss National Bank, which noted the central bank worked with the Swiss government and the Swiss Financial Market Supervisory Authority to bring about the combination of the country’s two largest banks. The terms of the deal will see Credit Suisse shareholders receive 1 UBS share for every 22.48 Credit Suisse shares they hold. “This ...
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