Phase – media

ViiV kicks off PhIII trial of two-drug HIV regimen

ViiV Healthcare, an HIV specialist firm majority owned by GlaxoSmithKline, has announced the launch of a late-stage study investigating the effectiveness of a two-drug regimen programme in patients with HIV.
- Source: pharmatimes
- 569
- February 12, 2018
Clinical Trial HIV Phase TANGO
AbbVie Scores Key Trial Win for RA Drug With One Fatal Event Reported

AbbVie’s investigational JAK1-inhibitor upadacitinib yielded positive top-line results in a Phase III trial as a monotherapy for rheumatoid arthritis patients. But the drug shows that it is still plagued by some safety concerns.
- Source: Biospace
- 577
- December 21, 2017
Clinical Trials inhibitor Phase rheumatoid arthritis
Amgen pulls ahead in sprint towards CGRP approval with promising PhIII migraine data

The frontrunner in the race to commercialize CGRP migraine medications just picked up some added momentum. Amgen $AMGN has published promising Phase III data that might lend to its approval, keeping the company — and its partner Novartis — ahead of its many competitors in the crowded space.
- Source: Endpts
- 511
- December 1, 2017
Aimovig Clinical Trials Phase
Novartis reports positive results from Phase III trial of Kisqali® (ribociclib) combination therapy

Novartis announced positive topline results from the global MONALEESA-7 trial, the second Phase III trial of Kisqali® (ribociclib) in advanced or metastatic breast cancer. The MONALEESA-7 trial met its primary endpoint of progression-free survival (PFS) in premenopausal women with hormone-receptor positive, human epidermal growth factor receptor-2 negative (HR+/HER2-) advanced breast cancer.
- Source: Novartis
- 808
- November 10, 2017
breast cancer Clinical Trials Kisqali Phase
Watch out Sanofi–Takeda’s new data on dengue vaccine is good news for PhIII trial

Prospects for Takeda’s dengue vaccine just turned brighter following fresh data from the company’s Phase II trial. For Takeda, the data is likely welcome considering the company already has a massive pivotal trial underway for the vaccine. For competitor Sanofi … perhaps not so welcome.
- Source: endpts
- 941
- November 7, 2017
antibody dengue Phase vaccine
Novartis pivotal data show children and adolescents with relapsing MS had an 82% lower relapse rate with fingolimod vs. interferon beta-1a

Novartis announced results from the Phase III PARADIGMS study, investigating the safety and efficacy of fingolimod vs. interferon beta-1a, in children and adolescents (ages 10 to <18) with relapsing multiple sclerosis (MS).
- Source: Prnewswire
- 668
- November 1, 2017
Clinical Trial Phase relapsing multiple sclerosis
Blood sugar pill shows promise

The pill form of the drug semaglutide is worth pursuing as a way to control blood sugar in patients with type 2 diabetes, say researchers.
- Source: medicalnewstoday
- 586
- October 18, 2017
diabetes glycemic Phase Researches semaglutide
Pfizer Presents Full Results from Phase 2 Study of Next-Generation Investigational ALK-Inhibitor Lorlatinib in ALK-Positive and ROS1-Positive Advanced Non-Small Cell Lung Cancer

Pfizer Inc. today announced full results from the Phase 2 clinical trial of the investigational, next-generation tyrosine kinase inhibitor lorlatinib that exhibited clinically meaningful activity against lung tumors and brain metastases in a range of patients with ALK-positive and ROS1-positive advanced non-small cell lung cancer (NSCLC), including those who were heavily pretreated.
- Source: Pfizer
- 692
- October 17, 2017
Clinical Trials inhibitor Phase tyrosine kinase
Merck launches frontline PhIII lung cancer study for Keytruda/Yervoy combo

Merck took a dominant position in frontline lung cancer with the approval of a combination of Keytruda and chemo. And it isn’t just waiting around to see if any combination of a PD-(L)1 with a CTLA4 can come along and knock it off its market-leading perch.
- Source: Endpts
- 615
- October 9, 2017
cancer Clinical Trials lung Phase
AbbVie Announces Positive Topline Results from Phase 3 MURANO study

AbbVie (NYSE: ABBV), a global research and development-based biopharmaceutical company, today announced that the Phase 3 MURANO study of VENCLEXTA/VENCLYXTO (Venetoclax) Tablets in combination with Rituxan® (rituximab) met its primary endpoint.
- Source: news.abbvie
- 662
- September 20, 2017
Clinical Trials CLL Phase rituximab Venetoclax

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