The upgraded McDonald criteria for multiple sclerosis (MS) has presented increased diagnoses in patients with clinically isolated syndrome (CIS), however a recent study of the criteria suggests that they may misguide to a number of false positive MS diagnoses in patients with a milder disease condition.
A research team from Washington University in St. Louis has been trying to investigate whether intermittent fasting could reduce multiple sclerosis symptoms, especially inflammation.
Multiple sclerosis is a neurological disease affecting the myelin sheath that surrounds nerve fibers in the central nervous system, composed of the brain, spinal cord, and optic nerve. Since myelin is destroyed, it creates lesions which leads to an interruption in communication between the brain cells.
Novartis is hoping multiple sclerosis candidate siponimod’s performance in secondary progressive patients can help it secure a blockbuster approval. And now it has more data to put toward that case.
Celgene has been slammed with a refuse-to-file letter from the FDA for ozanimod, the biggest late-stage drug it has in the pipeline.
Gossamer Bio is launching with $100 million in seed financing and two biotech heavy hitters as leadership.
Gene expression in specific cells and in specific regions can provide a more precise, neuroprotective approach than traditional treatments for neurological diseases. For multiple sclerosis, specifically, increasing cholesterol synthesis gene expression in astrocytes of the spinal cord can be a pathway to repair nerves that affect walking.
Monitoring disease activity in individuals with multiple sclerosis, either to predict flare-ups or to check treatment response, might be done with a simple blood test that measures levels of a nerve protein, according to a new study from Norway.
Alterations in gut bacteria at a young age could help to trigger and progress multiple sclerosis in people who are genetically predisposed to the autoimmune disease.
In the first randomized controlled trial in pediatric multiple sclerosis, fingolimod (Gilenya) significantly cut relapses compared with interferon beta-1a (Avonex), researchers reported here.
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