gene – media

Could epigenome editing prevent developmental disorders?

Source:https://www.medicalnewstoday.com/articles/327296.php Using a new type of genetic engineering tool called epigenome editing in mice, scientists have restored irregularities in the developing brain that arise from a gene mutation. New research in mice suggests that gene editing could prevent brain developmental disorders.Epigenome editing is a way of altering the expression, or reading, of genes without altering their underlying DNA code. A team from Johns Hopkins University in Baltimore, MD, led the Nature Communications study that focuses on the protein C11orf46. One of the study’s corresponding authors is Dr. Atsushi Kamiya, who is an associate professor of psychiatry and behavioral sciences at Johns Hopkins University School of Medicine. In humans, mutations in the section of DNA that contains the C11orf46 gene can lead to WAGR syndrome, a genetic condition that can cause intellectual disability and impair many systems of the body. The researchers found that C11orf46 directs the development of the corpus ...
- Source: drugdu
- 547
- December 13, 2019
C11orf46 gene
Prevail Therapeutics Announces $75 Million Series A Financing to Advance Gene Therapies for Patients with Parkinson’s and Other Neurodegenerative Diseases

Prevail Therapeutics, Inc. (Prevail), a biotechnology company developing gene therapies for patients with Parkinson’s disease and other neurodegenerative diseases, today announced a $75 million Series A financing.
- Source: silversteinfoundation.orgl
- 665
- March 13, 2018
financing gene Market Views Parkinson’s disease
Gene therapy shows promise against blood-clotting disease

Gene therapy has freed 10 men from nearly all symptoms of hemophilia for a year so far, in a study that fuels hopes that a one-time treatment can give long-lasting help and perhaps even cure the blood disease.
- Source: Usnews
- 526
- December 12, 2017
blood disease gene hemophilia
CRISPR/Cas9 gene editing can be used to eliminate entire chromosomes — a Q&A

As is well known, CRISPR/Cas9 is an effective tool for gene editing, and this method has been widely used for editing genes or genomic regions by targeting specific single-guide RNA (sgRNAs). We initially planned to use the CRISPR/Cas9 system to study the biological functions of Y chromosome genes.
- Source: biomedcentral
- 602
- December 5, 2017
CAS9 chromosome CRISPR gene Researches
Gene prompts cells to store fat, fueling obesity

Obesity is often attributed to a simple equation: People are eating too much and exercising too little. But evidence is growing that at least some of the weight gain that plagues modern humans is predetermined.
- Source: sciencedaily
- 656
- November 14, 2017
ankyrin-B gene obesity Researches
A Chinese Province Is Sequencing One Million of Its Residents’ Genomes

Authorities in the city of Nanjing, the capital of China’s Jiangsu province, announced at the end of October that they would sequence the genes of 1 million individuals to build a genetic database of Chinese residents. This project is part of the National Health and Medicine Big Data Nanjing Center, a new data storage facility under construction in the region.
- Source: futurism
- 598
- November 10, 2017
cancer chronic gene Market Views sequence
Four-in-one flu shot may mean lifelong protection against the flu

A vaccine combining centralized ancestral genes from four major influenza strains appears to provide broad protection against the dangerous ailment, according to new research by a team from the Nebraska Center for Virology.
- Source: Medicalxpress
- 739
- November 3, 2017
gene influenza strains Researches vaccine
NHS to fund gene therapy for ‘bubble babies’

The NHS will fund gene therapy for the first time, with a £500,000 treatment for “bubble baby syndrome”.
- Source: Telegraph
- 1,069
- October 26, 2017
gene immune defiency Market Views NHS therapy
Britain backs GSK’s gene therapy for ‘bubble boy’ syndrome

Gene therapy is designed to deliver a one-off cure for the patient and drugmakers are typically asking a hefty price that is comparable to the combined costs of alternative life-long treatment.
- Source: reuters
- 829
- October 23, 2017
ADA-SCID Company Insight gene Market Views NICE
FDA panel votes in favor of Spark’s blindness gene therapy

Spark Therapeutics Inc's experimental gene therapy for a rare form of blindness improves vision and should be approved, advisers to the Food and Drug Administration concluded on Thursday, paving the way for the first U.S. gene therapy for an inherited disease.
- Source: cnbc
- 1,050
- October 17, 2017
Company Insight gene inherited therapy

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