Early data shows CanSinoBIO’s inhaled COVID-19 vaccine triggers immune response

CanSinoBIO’s inhaled COVID-19 vaccine candidate was found to trigger immune responses with no serious side effects reported, according to an early-stage clinical study. The inhaled two-dose candidate is modified from CanSinoBIO’s injected COVID-19 jab Ad5-nCoV vaccine, which is already approved in China and other countries around the world. Results from a Phase I clinical trial, published in The Lancet, found that two-doses of the inhaled Ad5-nCoV vaccine can trigger a similar immune response to a single-dose of the injected version. The inhaled version was also found to trigger neutralising antibodies and T cell responses after one dose. The study also found that the inhaled version of the vaccine did not cause serious side effects, demonstrating an encouraging safety profile in the early-stage trial. A number of drugmakers are also developing inhaled treatments for COVID-19, including Verona Pharma. UK-headquartered Verona announced at the beginning of the year that it had completed enrolment ...

• Source: drugdu
• 973
• September 1, 2021