To develop small molecules which can target RNA mis-splicing in neurological diseases, Celgene is launching a $60 million collaboration with Skyhawk Therapeutics. Celgene received the option to develop up to five drug molecules for correcting neurological diseases such as Huntington’s disease, amyotrophic lateral sclerosis etc. The $60 million payment includes milestones, license fees and royalties.
NBTXR3 is composed of crystalline nanoparticles to amplify the efficacy of radiation therapy. The idea is to administer NBTXR3 as intra-tumoral injections before external beam radiation therapy, thereby increasing the antitumor effect, and thus preparing the patient for surgical resection.
Last Friday, pharma giant AstraZeneca announced that it had received the go-ahead from the Drug Controller General of India (DCGI) to import and market durvalumab (ImfinziTM) in India. The receipt of this permission paves the way for the launch of durvalumab (ImfinziTM) in India. Durvalumab which is a patented drug of Astra-Zeneca, received permission in India to provide treatment for patients with unresectable non-small cell lung cancer and metastatic urothelial carcinoma.
The IPO has provided the biotech major with the financial bandwidth to aggressively pursue its new generation of CAR-T variants on a broader level, with the advancement of several therapies or the start of clinical trials over the next couple of months.
Previous research claimed that consumption of vitamin D rich foods can reduce the risk factors of colorectal cancer. There was no proper evidence available to link vitamin D levels and colorectal cancer. Now, new research led by the Harvard T.H. Chan School of Public Health, adds convincing evidence to authenticate the link.
On Wednesday, a day after Keytruda got the thumbs up for cervical cancer, the drug was approved for treatment of a rare form of non-Hodgkins lymphoma patients who cancer returned after at least two previous treatment lines. Last year, Keytruda also got an indication for classical Hodgkin lymphoma.
On Sunday, at the American Society of Clinical Oncology’s annual meeting, Novartis revealed the final outcome, showing that among patients with HR-positive, HER2-negative breast cancer, adding Kisqali to fulvestrant kept the disease away for eight months longer than fulvestrant alone.
A research team from Cleveland Clinic in Ohio, US discovered a new test where ten types of cancer could be identified in a patient, well in advance.
A research team from the University of Ottawa in Canada revealed a safe and inexpensive treatment by employing Viagra and flu vaccines that might stop cancer revival. Tadalafil (Cialis), sildenafil (Viagra) in combination with Agriflu were used in the research work.
The research study revealed that tumor growth could be reduced by targeting the expression of Beta3-integrin along with microtubule-targeting agents (MTAs) chemotherapy. Beta3-integrin was the better anti-angiogenic target since it was expressed in tumor blood vessels, unlike normal cells.
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