After conducting a clinical trial study at Boston Children’s Hospital, scientists from Brown University recommended that a lonafarnib therapy could increase the survival rate of progeria patients. But the mode of action of lonafarnib is still uncertain.
An IPO for raising USD 115 million from public investors has been filed by Translate Bio. Proceeds garnered from the IPO will be used by Translate to trial an mRNA candidate designed to allow cystic fibrosis patients produce CTFR proteins.
Along with new drug partner Merck, the British drugmaker displayed results showing that adding Lynparza to Johnson & Johnson prostate cancer fighter Zytiga was a more potent disease-fighter than Zytiga alone. As compared to a time-frame of 8.2 months for solo Zytiga, the combo effectively prevented disease progression for 13.8 months.
Kathleen Miller, an energy-drink specialist from the University at Buffalo Research Institute on Addictions said, "Caffeine can be a great thing, at low doses; with the consumption of five 5-hour Energy drinks, however, you move past alert and awake, into the territory of jittery, anxious and heart palpitations." Caffeine doses higher than 5000 mg can lead to seizures, hallucinations and strokes.
The major component named epigallocatechin-3-gallate (EGCG) in green tea inhibits myeloperoxidase enzymes released by white blood cells during inflammatory bowel disease outbursts. But when green tea was consumed with iron, EGCG bound with the iron and the ability to inhibit myeloperoxidase was lost.
Hair dye poisoning is one of the major causes of self-injury. Chemical hair dye, especially paraphenylene-diamine can lead to edemas, rhabdomyolysis, acute metabolic acidosis and renal failure. Scientists from the University of Leeds have extracted natural dyes from blackcurrant waste, generated throughout Ribena blackcurrant production. This natural black dye with zero side effects could be used in fresh new hair dyeing technologies.
Professor James, the lead researcher said, “These gloves will be a game-changer for the healthcare industry, both public and private. I am delighted that my lifetime’s research into bacteria and antibiotic resistance has directly informed the science behind a practical tool that will have a major impact on medical care in the future.”
Updated clinical data on its T-cell therapies has been presented by Adaptimmune. The GlaxoSmithKline-partnered NY-ESO SPEAR T-cells have been linked by the latest readouts to a 50% partial response rate in heavily pretreated cancer patients and have led to the positioning of Adaptimmune for dialing up of dosing of two wholly owned assets.
Researchers are testing an mHealth wearable used for patients with asthma to see if the patch can help care teams detect pneumonia in patients undergoing radiation treatment for lung cancer.
The New York-based startup is aiming to digitize the equipment and to make the process easier through the ePrescribing platform. That way, the hospital doesn't spend time on faxing to communicate the order, and the patients and healthcare suppliers can get it quicker than they might have otherwise.
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