Search Results for “cardiovascular” – Page 34 – media

Hyperbaric Oxygen May Improve Heart Function in Long COVID

Marilynn Larkin Editor’s note: Find the latest long COVID news and guidance in Medscape’s Long COVID Resource Center. Hyperbaric oxygen therapy (HBOT) increased markers of heart function in a small randomized, controlled trial of patients with long COVID. Patients with reduced left ventricular global longitudinal strain (GLS) at baseline who received HBOT had a significant increase in GLS compared with those who received sham treatment. GLS is a measure of systolic function that is thought to be a predictor of heart failure-related outcomes. The study also showed that global work efficiency (GWE) and the global work index (GWI) increased in HBOT-treated patients, though not significantly. “HBOT is an effective treatment for diabetic foot ulcers, decompression sickness in divers, and other conditions, such as cognitive impairment after stroke,” Marina Leitman, MD, of the Sackler School of Medicine, Tel Aviv, Israel, told theheart.org | Medscape Cardiology. Her team also studied HBOT in ...
- Source: drugdu
- 114
- May 17, 2023
FDA Approves First-Of-Its Kind Drug to Ease Menopause Symptoms

An Astellas Pharma drug that treats hot flashes and night sweats from menopause is now approved by the FDA, a regulatory decision that makes the therapy the first one that hits a particular central nervous system target to ease the symptoms of this change in life. The Friday approval of the drug, fezolinetant, covers the treatment of moderate-to-severe vasomotor symptoms caused by menopause. Tokyo-based Astellas will market the once-a-day pill under the brand name Veozah. In an email, the company said the new drug will carry a wholesale price of $550 for a 30-day supply. Astellas expects Veozah will become available within three weeks. Menopause brings a decline in the production of estrogen and progesterone. The resulting hormonal imbalance can affect the way the body regulates body temperature, leading to hot flashes, the sudden and intense feelings of warmth. While hormone therapy is standard treatment for such vasomotor symptoms, ...
- Source: drugdu
- 150
- May 16, 2023
Steroids linked to long-lasting heart disease risk and worse quality of life

Anabolic steroids not only can cause serious side effects during use, such as heart failure and depression, but can continue being harmful years after stopping, according to two studies presented at the 25th European Congress of Endocrinology in Istanbul. These studies were carried out by researchers from the Copenhagen University Hospital Rigshospitalet who investigated the impact of anabolic steroids in former users. Anabolic steroids—synthetic hormones that mimic the naturally-occurring sex hormone testosterone—are used to increase muscle mass and boost athletic performance. These performance-enhancing drugs have harmful side effects, for instance in men these include breast growth, hair loss, lower testosterone levels, erectile dysfunction, and an increased risk of heart disease, stroke, and liver or kidney failure. However, not much is known about the effects years after stopping their use. In one study, the researchers examined 64 healthy men, between the ages of 18 and 50, who did recreational strength training ...
- Source: drugdu
- 110
- May 16, 2023
COVID-19 that occurs after vaccination carries a much lower risk of severe illness

Scientists have developed several vaccines to prevent infection by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causal agent of the ongoing coronavirus disease 2019 (COVID-19) pandemic. Previous studies have shown that although vaccine-induced immunity declines over time, vaccine effectiveness (VE) against severe COVID-19 persists for extended periods. Background Several studies have indicated that COVID-19 vaccines were less effective in preventing severe illness in older adults and otherwise immunocompromised patients. Nevertheless, COVID-19 vaccination has reduced disease severity among patients hospitalized due to SARS-CoV-2 infection. Fully vaccinated people who were hospitalized due to symptomatic COVID-19 were less likely to require mechanical ventilation, intensive care unit (ICU) admission, or die as compared to unvaccinated individuals. However, there remains a lack of studies that have evaluated the relationship between COVID-19 booster vaccination and disease severity using large samples infected with different SARS-CoV-2 variants. About the study A recent Journal of ...
- Source: https://www.news-medical.net/news/20230511/COVID-19-that-occurs-after-vaccination-carries-a-much-lower-risk-of-severe-illness.aspx
- 122
- May 14, 2023
Simple Insulin Sensitivity Score Stratifies Post-CABG Risk

Marlene Busko, for Medscape May 10, 2023 The study covered in this summary was published on Research Square as a preprint and has not yet been peer reviewed. Key Takeaways People with a higher metabolic score for insulin resistance (METS-IR) had a significantly greater rate of major adverse cardiac events (MACE) after they underwent coronary artery bypass graft (CABG) surgery and independent of traditional cardiovascular risk factors in a Chinese study. Following CABG, patients in the highest quartile for METS-IR had a nearly twofold increased risk of MACE during follow-up compared with patients in the lowest METS-IR quartile after adjusting for potential confounders. Why This Matters CABG is standard treatment for people with multivessel and left main coronary artery disease and significantly improves cardiovascular outcomes, but long-term survival after CABG remains poor. This is the first reported study to examine the relationship between METS-IR and MACE in patients following CABG surgery. The results suggest that METS-IR is a simple and ...
- Source: drugdu
- 126
- May 12, 2023
AstraZeneca’s heart failure treatment approved for expanded use in US

AstraZeneca’s (AZ) Farixga (dapagliflozin) has been approved for extended use in the US, meaning adult patients with heart failure (HF) can benefit from the treatment regardless of their left ventricular ejection fraction status (LVEF). Farxiga, sold as Forxiga in certain markets, was previously approved in the US for HF patients with reduced ejection fraction (HFrEF) which is equal to or less than 40%. HF affects approximately seven million people in the US and is associated with substantial morbidity and mortality, with chronic HF the leading cause of hospitalisation for those over the age of 65. Roughly half of all HF patients have mildly reduced ejection fraction (HFmrEF) or preserved ejection fraction (HFpEF), with few therapeutic options available. As well as the greater risk of death and hospitalisations, patients with HFmrEF or HFpEF experience an especially high burden of symptoms and physical limitations. The US Food and Drug Administration’s (FDA) ...
- Source: drugdu
- 144
- May 12, 2023
Most effective treatment for excessive daytime sleepiness found

McMaster University researchers Dena Zeraatkar and Tyler Pitre have found that the drug solriamfetol is the most effective treatment for excessive daytime sleepiness (EDS) for people with obstructive sleep apnea (OSA). The standard treatment for OSA is a positive airway pressure (PAP) mask that uses compressed air to support lung airways during sleep. However, some people with OSA still experience EDS and may benefit from anti-fatigue medication. Zeraatkar and Pitre published their results in the Annals of Internal Medicine. “The most important thing that people with OSA should do is use their PAP machine, but if they are still sleepy there are options in the form of medications that can reduce their tiredness.” Tyler Pitre, first author, resident physician in internal medicine at McMaster University and incoming respirology fellow at the University of Toronto “Fifteen to 30 per cent of people in North America have a diagnosis ...
- Source: drugdu
- 118
- May 11, 2023
New study reveals the best diets for a healthy heart

In a recent study published in the journal Vascular Health and Risk Management, researchers discuss the various non-traditional and traditional practices, as well as the socioeconomic and food insecurity-related limitations associated with adopting diets for heart health. Background Despite considerable progress in medicine and dietary interventions that have improved cardiovascular health, cardiovascular disease remains one of the most prevalent causes of mortality in the United States. Early studies on the association between diet and cardiovascular health reported that a diet rich in fish, vegetables, grains, fruits, and beans was linked to a lower rate of myocardial infarctions. Moreover, the consumption of vegetables and fruits, along with regular exercise, was associated with 40% lower rates of myocardial infarction. Hypertension, excess abdominal fat, dyslipidemia, and type 2 diabetes are some of the risk factors for cardiometabolic diseases that can be modified through changes in the diet. In the U.S., ...
- Source: drugdu
- 138
- May 5, 2023
Wearable ultrasound researchers report breakthrough in deep tissue monitoring

This wearable ultrasound device for monitoring tissue stiffness measures 23 mm x 20 mm x 0.8 mm. [Photo courtesy of University of California San Diego] Wearable ultrasound researchers have developed a stretchable ultrasonic array for serial, noninvasive, 3-D tissue imaging with a penetration depth of up to 4 cm. The latest device out of Sheng Xu’s lab at the University of California San Diego (UCSD) is able to frequently evaluate the stiffness of human tissue. It could be used to measure the progression of cancer, to monitor muscles, tendons and ligaments, and assess the effectiveness of liver and cardiovascular treatments. Xu is commercializing the technology through a UCSD spinoff called Softsonics. “We integrated an array of ultrasound elements into a soft elastomer matrix and used wavy serpentine stretchable electrodes to connect these elements, enabling the device to conform to human ...
- Source: drugdu
- 136
- May 5, 2023
Quest to Reach Another Segment in Liquid Biopsy with New M&A

Omar Ford Quest Diagnostics is diving into a quickly growing segment of liquid biopsy with its latest M&A prospect. The Secaucus, NJ-based company announced a definitive agreement to acquire Haystack Oncology in an all-cash equity transaction. Quest will pay $300 million in cash at closing and Haystack has the potential to obtain up to an additional $150 million in performance milestones. If the deal were to close, then Quest would inherit Baltimore, MD – based Haystack’s minimal residual disease testing technology. MRD testing is a specific category of liquid biopsy that identifies circulating tumor DNA (ctDNA) in the bloodstream of patients following surgery and treatment for cancer. In a prospective, multi-institution study published in the New England Journal of Medicine in June 2022, an earlier version of the Haystack technology demonstrated the ability to better identify patients with residual disease for adjuvant chemotherapy after surgery for stage II colon cancer, thereby reducing ...
- Source: drugdu
- 137
- May 1, 2023

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