The adjuvanted trivalent influenza vaccine Fluad for use in people aged 65 years or older has been cleared by the Medicines and Healthcare products Regulatory Agency.
According to the Instant Drug Database, last week (November 4th to November 10th), at least four emerging companies dedicated to innovative drug research and development worldwide announced the completion of a new round of financing, including three Chinese companies. These emerging companies that have gained favor in the capital market are developing drug types such as gene therapy drugs, iPSC cell therapy drugs, peptide vaccines, and antibody conjugated drugs (ADCs) with dual payloads. Kanglin Biotechnology Financing round: Series A Financing amount: 150 million yuan On November 8th, Kanglin Biotechnology (Hangzhou) Co., Ltd. (referred to as “Kanglin Biotechnology”) announced the completion of a 150 million yuan Series A financing, jointly invested by Zhejiang Province’s “4+1” Biomedical and High end Device Industry Fund and old shareholder Zhejiang Miyin Investment Management Co., Ltd. Kanglin Biology was founded in 2015, focusing on the R&D and commercialization of innovative drugs for gene therapy, targeting diseases ...
The third quarter of 2024 is an epoch-making watershed. An unprecedented large-scale stagnation has occurred in the consumer healthcare field. From medical beauty, ophthalmology, dentistry, pharmaceutical retail, branded Chinese medicine, growth hormone to self-funded vaccines, the leaders in various segments have become old and collectively lost their growth potential. The mismatch between business model, product structure and consumer market is one of the reasons for the predicament, but it is so difficult for a company to get out of the path dependence that created its former glory. Now there are two problems. First, how does the market value companies that have lost their growth but are still profitable? When a company stops growing, the only investment attraction is high dividends, but consumer healthcare companies are almost all stingy. Second, when will consumption pick up? When will the consumption inflection point come? Japan’s situation from 1990 to 1997 is inspiring. Consumption ...
On the morning of November 6th, at the 7th China International Import Expo (CIIE), Jean Christophe Pointeau, President of Pfizer China, a multinational pharmaceutical giant, revealed that the company will launch the “Pfizer China 2030 Strategy” during this year’s CIIE. From 2025 to 2030, Pfizer will invest 1 billion US dollars, about 7.5 billion yuan, in China. Pfizer will continue to invest in accelerating innovation, improving diagnostic capabilities and treatment standards, and promoting the development of the local biotechnology industry to support the ‘Healthy China 2030’ initiative. This strategy is based on three pillars: firstly, accelerating the launch of innovative drugs and introducing breakthrough innovative products more quickly; The second is to continue to improve diagnostic capabilities and treatment standards, especially in rural areas, and promote the connection between first-class hospitals and rural areas; The third is to promote the development of the local biotechnology industry. As an important part ...
On October 31, CSPC Pharmaceutical Group issued a third-quarter profit warning announcement. It is expected that the company’s net profit in the first three quarters of this year will decrease by about 16% year-on-year from 4.495 billion yuan in the same period last year. In total, CSPC Pharmaceutical Group’s net profit in the first three quarters of this year is about 3.776 billion yuan. According to the interim report, CSPC Pharmaceutical Group’s revenue in the first half of the year was 16.284 billion yuan, a year-on-year increase of 1.27%, and its net profit was 3.02 billion, a year-on-year increase of 1.8%. According to this calculation, the net profit in the third quarter was only 760 million yuan, while the same period last year, this figure was 1.528 billion yuan. In other words, the net profit in the third quarter of this year was halved, a year-on-year decrease of 50%. As ...
Disclaimer: Due to limited proficiency, errors are inevitable, or some information may not be timely. Please feel free to leave a message to indicate. This article only provides an introduction to medical and health-related drugs, and does not recommend treatment plans (if applicable); This article does not constitute any investment advice. On the morning of November 6th, at the 7th China International Import Expo (CIIE), Jean Christophe Pointeau, President of Pfizer China, a multinational pharmaceutical giant, revealed that the company will launch the “Pfizer China 2030 Strategy” during this year’s CIIE. From 2025 to 2030, Pfizer will invest 1 billion US dollars, about 7.5 billion yuan, in China. Pfizer will continue to invest in accelerating innovation, improving diagnostic capabilities and treatment standards, and promoting the development of the local biotechnology industry to support the ‘Healthy China 2030’ initiative. This strategy is based on three pillars: firstly, accelerating the launch of ...
Preface B cells are the only cell type capable of differentiating into antibody secreting cells (plasma cells), and they can also present antigens to T cells and produce cytokines. By producing cytokines, B cells affect multiple aspects of immunity: cytokines derived from B cells, including lymphotoxins, are crucial for the individual development, homeostasis, and activation of secondary lymphoid organs, as well as the development of tertiary lymphoid tissue in ectopic sites; Other cytokines derived from B cells, such as interleukin-6 (IL-6), interferon – γ, and tumor necrosis factor, can affect the development of effector cells and memory CD4+T cell responses; Finally, B cells can regulate inflammatory immune responses by secreting IL-10 and IL-35, and “regulatory B cells” are the main source of inhibitory cytokines derived from these B cells in the body. The role of B cells in tissue development and repair Lymphatic organogenesis is mainly regulated by lymphoid tissue ...
Multinational pharmaceutical companies are under increasing pressure. Especially when the US market, the world’s largest pharmaceutical market, has undergone tremendous changes due to the Inflation Reduction Act, the importance of the Chinese market has once again been highlighted. However, all signs indicate that it is becoming increasingly difficult to get a bigger piece of the pie in the Chinese market. In recent years, the reform policies introduced by the state at the pharmaceutical level have exceeded the changes in the previous decades. The continued advancement of medical reform policies such as medical insurance negotiations and national centralized procurement, coupled with the epidemic, anti-corruption, capital winter, local generic drugs, and the rise of innovative forces, have intensified the challenges of the entire industry. Therefore, we see that the past two years have become a strategic turbulence period for MNCs in China. While tapping the potential of the domestic market, they are ...
Breakthrough treatment varieties refer to innovative drugs or improved new drugs used to prevent and treat diseases that seriously endanger life or seriously affect quality of life, and for which there are no effective prevention and treatment methods or sufficient evidence to show significant clinical advantages compared to existing treatment methods. After obtaining this recognition, it can accelerate the review process, accelerate the drug development process, and solve the unmet clinical needs of patients. In the past October, the CDE official website plans to include 5 breakthrough therapy varieties, including 1 therapeutic vaccine, 3 ADC drugs, and 1 monoclonal antibody drug. The following are introductions to 5 innovative drugs for reference only. 1. TVAX-008: Hepatitis B On October 14th, Nanjing Yuanda Weixin Biopharmaceutical Co., Ltd. TVAX-008 applied to be included in the breakthrough treatment category, suitable for the treatment of chronic hepatitis B virus (HBV) infection. TVAX-008 is a therapeutic ...
The success and failure of COVID-19 are the market’s summary of Pfizer in the past few years. In 2022, COVID-19 vaccines and COVID-19 oral drugs brought Pfizer up to $57 billion in revenue. Relying on the wealth brought by COVID-19 products, Pfizer’s revenue exceeded $100 billion this year, setting a new record for the highest revenue of major pharmaceutical companies. However, as the COVID-19 pandemic dissipated, the global market demand for COVID-19 products fell sharply, and Pfizer was the first to bear the brunt. Faced with the “COVID-19 cliff”, Pfizer had to continue to lower its revenue expectations, and the company’s stock price continued to fall. Last year, it fell by more than 40% throughout the year, and its market value evaporated by nearly $130 billion. In this year’s third quarter report, Pfizer handed in a report card that far exceeded market expectations. Revenue in the third quarter reached $17.7 ...
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