PharmaFocus Today – Page 42 – media

New neuro-sensing technique captures brainwaves from within veins

Researchers at The University of Osaka have developed a groundbreaking, minimally invasive method for recording brain activity through blood vessels. This technique could potentially transform the diagnosis and treatment of neurological conditions like epilepsy and paving the way for advanced brain-computer interfaces. It eliminates the need for invasive open-brain surgery, offering a safer and more accessible way to monitor and stimulate brain function. Current methods for directly measuring brain activity require invasive procedures, either removing part of the skull to place electrodes on the brain surface or inserting electrodes directly into brain tissue. While non-invasive methods like EEG exist, they lack the precision needed for detailed analysis. This new method bridges the gap, offering high-fidelity recordings without the risks associated with traditional invasive approaches. The research team, led by Professor Takufumi Yanagisawa used a catheter to insert ultra-thin wire electrodes into the cortical and deep veins of pig brains. They ...
- Source: drugdu
- 139
- September 22, 2025
Why Mosquitos Might Be Attracted To You

By Deanna Neff HealthDay ReporterSATURDAY, Sept. 20, 2025 (HealthDay News) — Researchers in the Netherlands turned a major music festival into an unexpected laboratory to investigate a question that has long puzzled scientists and bug-bitten individuals alike: What makes some people more irresistible to mosquitoes than others? For three consecutive days at the Lowlands festival in Biddinghuizen, Netherlands, scientists set up a unique pop-up research site inside a series of shipping container laboratories. Instead of waiting for their favorite band, hundreds of festivalgoers lined up to volunteer for the “Mosquito Magnet Trial,” a study designed to measure their personal attractiveness to the insects. Inside the make-shift lab from 9 a.m. to 10 p.m. each day, groups of participants rested their arms against transparent acrylic boxes that had caged mosquitoes. As the insects responded to the human scent, a camera and computer system recorded mosquito movements and calculated a unique attraction ...
- Source: drugdu
- 96
- September 22, 2025
Zhengda Tianqing targets 9.2 billion yuan drug

On September 15, the injectable degarelix acetate (Qinglishu) independently developed by Zhengda Tianqing obtained the drug registration certificate issued by the National Medical Products Administration (NMPA) for use in prostate cancer patients who require androgen deprivation therapy. As the original drug in this category, degarelix acetate (fermonger)’s global sales exceeded US$1.3 billion (approximately RMB 9.2 billion) in 2024. Is Zhengda Tianqing, the “pioneer in anti-tumor innovation”, brewing a blockbuster drug? 01 Approved for listing in three locations The original developer of Degarelix Acetate for Injection is Ferring Pharmaceuticals. As a selective gonadotropin-releasing hormone receptor (GnRHR) antagonist, the clinical value of Degarelix Acetate in the treatment of prostate cancer has long been recognized worldwide. This drug can effectively reduce the release of gonadotropin and testosterone by reversibly binding to the GnRH receptors in the pituitary gland, thereby inhibiting the growth and spread of prostate cancer cells from the root. Especially in ...
- Source: drugdu
- 214
- September 18, 2025
Announcement on the Holding Subsidiary Obtaining Medical Device Registration Certificate

September 17th, Meikang BioAccording to the announcement, the company’s holding subsidiary Jiangxi Meikang Shengde Biotechnology Co., Ltd. recently obtained the ” Medical Device Certificate of the People’s Republic of China” issued by the Jiangxi Provincial Drug Administration.Registration Certificate ( In Vitro DiagnosticThe product names are: tissue plasminogen activator-inhibitor 1 complex detection kit (chemiluminescent immunoassay), thrombin-antithrombin complex detection kit (chemiluminescent immunoassay), thrombomodulin detection kit (chemiluminescent immunoassay), plasmin-α2 plasmin inhibitor complex detection kit (chemiluminescent immunoassay). https://finance.eastmoney.com/a/202509173516207639.html
- Source: drugdu
- 128
- September 18, 2025
Plans to invest RMB 42.74 million in Wuhan Huajiyuan to advance clinical trials of the therapeutic antihypertensive vaccine (HJY-ATRQβ-001) project

Meijing AI News, September 17, Saili Medical(603716.SH) announced plans to increase capital by 42.7429 million yuan in its subsidiary, Wuhan Huajiyuan Biotechnology Development Co., Ltd. Upon completion of the capital increase, the company’s stake in Wuhan Huajiyuan will increase to 41%. Concurrently, the company’s actual controller, Wen Wei, plans to acquire a 10% stake in Wuhan Huajiyuan shareholder Sun Danping for 27.2 million yuan, at a post-capital valuation of 272 million yuan. The company and its actual controller, Wen Wei, will contribute a total of 69.9429 million yuan in this transaction. The target company will be consolidated as a controlled subsidiary of the company in 2026. All parties agreed to actively advance the various phases of clinical trials for the target company’s therapeutic antihypertensive vaccine (HJY-ATRQβ-001) project and work together to develop the target company’s business. Upon completion of the capital increase, all parties pledged to actively conduct research and ...
- Source: drugdu
- 128
- September 18, 2025
Eli Lilly wins again! Oral weight loss drug outperforms oral sirolimus in head-to-head tria

Eli LillyTwo star weight loss pillsThe “one-on-one” battle has spread to the field of oral drugs, and the pressure has been put on Novo Nordisk.. On September 17, Eli Lilly announced positive top-line results from the Phase III ACHIEVE-3 study. The 52-week study compared orforglipron (12 mg and 36 mg) with oral semaglutide (7 mg and 14 mg) in terms of glycemic control and weight loss across four active treatment groups. At 52 weeks, orforglipron achieved its primary endpoint and all key secondary endpoints across all dose groups, demonstrating superiority over oral semaglutide in terms of improvements in glycated hemoglobin (A1C) and weight. Orforglipron is an oral small molecule GLP-1 receptor agonist from Eli Lilly , and Rybelsus is an oral GLP-1 drug from Novo Nordisk . The aforementioned study was a head-to-head comparison. A head-to-head study can be considered a direct comparison of the two drugs’ efficacy and safety. ...
- Source: drugdu
- 169
- September 18, 2025
Hengrui’s breakthrough hepatitis B therapy arrives

On September 15, the CDE official website announced that Hengrui Medicine’s new generation of liver-targeted hepatitis B virus siRNA drug HRS-5635 injection is planned to be included in the breakthrough therapy variety for the treatment of chronic hepatitis B. Chronic hepatitis B (CHB) is a chronic inflammatory liver disease caused by persistent infection with the hepatitis B virus (HBV). According to the World Health Organization, 254 million people worldwide were living with chronic HBV infection in 2022, with approximately 1.2 million new infections. In China, a major country with a high incidence of CHB, epidemiological data from 2020 estimated that there were approximately 75 million HBV carriers, of whom approximately 30 million were infected but unaware. Of those diagnosed, 17 million required antiviral treatment, but only 3 million received it. In addition, HBV infection significantly increases the risk of developing cirrhosis and liver cancer. The proportion of cirrhosis and liver ...
- Source: drugdu
- 260
- September 17, 2025
Progress in ASC30 Research

On September 17, Ascletis Pharma-B (01672) issued an announcement, announcing that it reported the results of a 28-day multiple-dose escalation study of its ASC30 oral small molecule GLP-1R agonist at the 61st European Association for the Study of Diabetes Annual Meeting held in Vienna, Austria on September 16, 2025. In MAD Cohort 2, once-daily oral administration of ASC30 demonstrated a placebo-adjusted mean weight loss of 6.5% from baseline after 28 days of treatment, compared to a mean weight loss of 4.5% in MAD Cohort 1. The study was well-safe and well-tolerated, with only mild to moderate gastrointestinal adverse events and no serious adverse events. https://finance.eastmoney.com/a/202509173515879467.html
- Source: drugdu
- 103
- September 17, 2025
Sabin strain inactivated polio vaccine approved for marketing, enriching product portfolio

　　China Securities Intelligence Financial News Kangtai Biological(300601) announced on the evening of September 15 that its wholly-owned subsidiary Beijing Minhai Biotechnology Co., Ltd. received the “Drug Registration Certificate” issued by the State Food and Drug Administration, and its developed Sabin strain inactivated polio vaccine (Vero cell) was officially approved for marketing. 　　According to the announcement, the vaccine is used to prevent acute infectious diseases caused by polio virus. After vaccination, it can stimulate the body to produce immunity against polio virus and is used to prevent poliomyelitis caused by polio type I, II and III virus infection. 　　According to the website of the National Medical Products Administration, the manufacturers of the vaccine currently on the market in China include Beijing Sinovac BiotechProducts Co., Ltd., Beijing Biological ProductsInstitute Co., Ltd., Institute of Medical Biology, Chinese Academy of Medical Sciences. 　　The announcement stated that the approval of the above-mentioned vaccines for marketing ...
- Source: drugdu
- 130
- September 17, 2025
Borrui Pharmaceuticals’ application for clinical trial of BGM0504 tablets in overweight/obese adults has been approved.

Borrui Pharmaceuticals(688166) announced on the evening of September 15th that its wholly-owned subsidiary, Borrui Pharmaceutical, recently received a “Notice of Approval for Drug Clinical Trial” from the National Medical Products Administration (NMPA), authorizing the clinical trial of Borrui Pharmaceutical’s BGM0504 tablets in overweight/obese adults. BGM0504 is a dual agonist of the GLP-1 (glucagon-like peptide 1) and GIP (glucose-dependent insulinotropic polypeptide) receptors independently developed by the company. It activates the downstream pathways of GIP and GLP-1, resulting in biological effects such as blood sugar control, weight loss, and the treatment of non-alcoholic steatohepatitis (NASH), demonstrating potential for the treatment of various metabolic diseases. BGM0504 injection is currently in Phase III clinical trials in China for both type 2 diabetes and weight loss. BGM0504 tablets are the oral formulation of BGM0504. As of the date of this announcement, no oral formulations targeting this target have been approved for marketing globally. https://finance.eastmoney.com/a/202509153513828386.html
- Source: drugdu
- 138
- September 17, 2025

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