Drugdu.com expert’s response: The stimulatory effect of ornidazole and sodium chloride injection on blood vessels is relatively mild, but it may still have some impact on blood vessels in certain circumstances. In clinical practice, to minimize the potential irritation to blood vessels, it is generally recommended to control the infusion rate of ornidazole and sodium chloride injection. For example, for a 100ml injection, the infusion time should typically not be less than 30 minutes. If the infusion rate is too fast, it may cause painful or tingling sensations due to blood vessel irritation. Apart from direct irritation to blood vessels, ornidazole and sodium chloride injection may also cause other adverse reactions. These reactions may involve the digestive system (such as nausea, vomiting, abdominal pain, diarrhea, and other gastrointestinal discomforts), the nervous system (such as dizziness, headache, convulsions, drowsiness, confusion, and other symptoms), the blood system (such as decreases in white ...
Lilly stated in a press release on December 4th that in a head to head randomized controlled trial, its weight loss drug Zepbound was more effective in weight loss than its competitor Novo Nordisk’s Wegovy. This result is not surprising for scientists and doctors who are closely monitoring the rise of glucagon like peptide-1 (GLP-1) weight loss drugs. This randomized controlled trial also reflects the results of diabetes drugs from the two companies. These drugs use the same active ingredients and are sold under the brands of Mounjaro and Ozempic respectively. Similar results have been observed in observational studies and previous clinical trials comparing drugs with placebos separately. However, recording the differences between Zepbound and Wegovy in a rigorous manner is still an important step, especially as such a comparison may allow Lilly to claim in marketing that Zepbound has better therapeutic effects. This can help Lilly win ...
In today’s rapidly accelerating industrial automation process, the performance and quality of process sensors play a crucial role in the precision, efficiency, and reliability of production. The newly launched 50 series process sensors by Bao Meng have numerous unique advantages, making them stand out among many similar products and once again attracting industry attention. The Baumer 50 series process sensors embody cutting-edge technology and innovative design concepts, with many outstanding features such as compact design, excellent performance, and easy operation. This series of high-performance sensors adheres to the consistent style of Baumer products, adopting a simple and unified operation mode, allowing operators to quickly and conveniently complete debugging work and easily get started in the subsequent use process. It covers the market tested PAC50 conductivity sensor, as well as the newly developed PT55 temperature sensor and PP56 pressure sensor. PP56 pressure sensor The PP56 pressure sensor has demonstrated an ...
On December 4, local time, Eli Lilly announced the results of the Phase 3b clinical study of SURMOUNT-5. The subjects in the weight loss version of Zepbound lost 50.3 pounds (22.8 kg) at week 72, and the subjects in the weight loss version of Wegovy lost 33.1 pounds (15 kg) during the same period. Compared with semaglutide, the average weight loss effect of Zepbound is 47% higher. SURMOUNT-5 is a multicenter, randomized, open-label, head-to-head study designed to evaluate the efficacy and safety of Zepbound and semaglutide in obese or overweight adults with at least one comorbidity such as hypertension, dyslipidemia, obstructive sleep apnea or cardiovascular disease, and without diabetes. A total of 751 participants were recruited in the trial and assigned in a 1:1 ratio to receive the maximum tolerated dose of tirpotide (10mg or 15mg) or semaglutide (1.7mg or 2.4mg). At 72 weeks, the average weight loss ...
According to the official website of NMPA, Zambon/Parexel Pharmaceuticals’ Safinamide Mesylate Tablets have been approved for marketing. According to public information, Safinamide is a drug used to treat Parkinson’s disease. Parkinson’s disease is the second most common neurodegenerative disease and a common activity disorder. Its main cause is a lack of dopamine. According to statistics, about 1-2% of people over 65 years old suffer from Parkinson’s disease worldwide. In China, there are more than 3 million Parkinson’s disease patients, and the incidence rate increases with age. It is predicted that the number of Parkinson’s patients in China will exceed 5 million in 2030. The “OFF” period is a common phenomenon in the middle and late stages of Parkinson’s disease. Patients usually show severe aggravation of symptoms such as muscle stiffness, tremor and movement difficulties. According to statistics, about 75% of Parkinson’s patients in the middle and late stages will ...
At the end of 2011, the first drug of ranibizumab entered the Chinese market. As a biological drug for the treatment of fundus macular degeneration, it has a monopoly advantage in the market and is priced at nearly 10,000 yuan per bottle. Originally, multinational pharmaceutical companies wanted to make a fortune from this star product in the huge Chinese market, but no one could have imagined that a Chinese local company that “sticks to its research and development” – Kanghong Pharmaceutical would overtake others and bring down the price of the drug in one fell swoop… A pioneering journey of “a narrow escape from death” In 1994, Kanghong was established in the wave of reform and opening up. This innovative pharmaceutical company started with traditional Chinese medicine. Its Songling Xuemaikang Capsule is an exclusive patented Chinese medicine for the treatment of hypertension and primary hyperlipidemia. At the same time, in ...
On December 1st, Siemens Healthineers and DeepHealth officially announced a major strategic partnership, with the latter partnering with Siemens Healthineers to implement SmartTechnology by embedding AI driven health informatics into workflows and imaging hardware ™, Bringing innovative changes to the field of ultrasound operations. Data shows that DeepHealth is a wholly-owned subsidiary of RadNet, a global leader in AI driven health informatics, dedicated to providing AI driven health informatics to achieve breakthroughs in the nursing field through imaging. RadNet is also the largest third-party independent medical imaging company in the United States. 01. DeepHealth collaborates with Siemens Healthineers At present, the high-capacity ultrasound nursing environment is facing severe challenges such as labor shortage, operator limitations and fatigue, and unstable image acquisition quality. These problems may not only delay accurate diagnosis, but also lead to unnecessary examination processes. In response to this situation, the remote collaboration and image acquisition command center ...
Recently, according to authoritative financial media such as Kyodo News, legendary giant Toshiba is planning to implement a large-scale layoff in Japan, with an expected number of layoffs exceeding 3000, accounting for about 5% of its total Japanese employees. Toshiba further stated that this round of layoffs will mainly target employees aged 50 and above, and will be carried out through voluntary resignation. For employees who choose to resign before the end of November this year, the company will provide additional severance pay and promise to provide a two-year re employment support service to alleviate their worries. It is worth noting that this is not the first time Toshiba has taken large-scale layoffs this year. As early as May this year, Toshiba announced that it would lay off up to 5000 employees in Japan, accounting for about 6%, with the aim of accelerating the restructuring process and reducing costs to ...
On November 27, Huadong Medicine announced that its Sometuximab Injection and Rilonacept for Injection were approved for marketing by NMPA. On the same day, the drug registration and marketing authorization application for CD19 CAR-T candidate IM19 chimeric antigen receptor T cell injection (hereinafter referred to as “IM19”) was also accepted by NMPA. Sometuximab Injection (ELAHERE®/ELAHERE®) is used for the indication of folate receptor α-positive platinum-resistant ovarian cancer (PROC) that has received 1-3 lines of systemic treatment in the past; Rilonacept for Injection (trade name: Yanduo®/ARCALYST®) is used to treat cold pyrine-associated periodic syndrome (CAPS) in adults and adolescents aged 12 years and above, including familial cold autoinflammatory syndrome (FCAS) and Muckle-Wells syndrome (MWS). Suomitoximab is a drug targeting FRα targets and is the only platinum-resistant recurrent ovarian cancer treatment drug on the market in the world. According to public information, Suomitoximab can recognize target proteins on the surface of tumor ...
Drugdu.com expert’s response: The development trend of the medical device industry demonstrates diversification and a positive upward trajectory. Ⅰ. Continuous Growth in Market Size In recent years, the market size of the global and Chinese medical device industries has maintained a rapid growth trend. The market size of China’s medical device industry has grown from 623.5 billion yuan in 2019 to 1,035.8 billion yuan in 2023, with a significant annual compound growth rate. It is projected that the market size will further expand in 2024. Especially in the submarket of medical instruments, it同样 exhibits a rapid growth trend, and it is estimated that the market size of China’s medical instruments will reach 415 billion yuan by 2024. Ⅱ. Accelerated Advancement Towards High-End Products Guided by high-quality development policies, China’s medical device industry is accelerating its move towards high-end products. Innovative medical device products are emerging continuously, such as biomaterial devices, ...
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