Megan Brooks Using a mobile phone to make or receive calls for just 30 minutes a week is associated with an increased risk of developing hypertension, a large observational study using UK Biobank data suggests. The study showed adults who spent that at least a half-hour per week on their mobile phone had a 12% increased risk of developing hypertension, whereas those who spent more than 6 hours weekly had a 25% increased risk, compared with a weekly usage time of under 5 minutes. The investigators caution, however, that the results are purely “hypothesis-generating” and require confirmation, the researchers say. Experts not involved in the study also urged caution in interpreting the results. “This study should not be considered a basis to recommend reducing time spent using mobile phones to make calls as a technique to avoid hypertension,” Matthew Tomey, MD, cardiologist, Icahn School of Medicine at Mount Sinai in New ...
By Sean Whooley Leave a Comment [Screenshot from video provided by Nortwestern Medicine] Northwestern Medicine shared results from a first-in-human clinical trial for a skull-implantable ultrasound device that supports chemotherapy delivery. The device opened the blood-brain barrier to repeatedly permeate large, critical regions of the human brain. This enabled the delivery of chemotherapy injected intravenously. With the patient awake, a four-minute procedure opens the blood-brain barrier and patients go home after a few hours. Results from the Northwestern study demonstrated both a safe and well-tolerated treatment. Some patients even reached up to six cycles of chemotherapy treatment. The paper published on May 2 in The Lancet Oncology. More about the chemotherapy study The researchers say this marks the first study to successfully quantify the effect of ultrasound-based blood-brain barrier opening on the concentrations of chemotherapy in the human brain. Opening the blood-brain barrier led to approximately a four-to-six-fold increase in drug concentrations ...
This wearable ultrasound device for monitoring tissue stiffness measures 23 mm x 20 mm x 0.8 mm. [Photo courtesy of University of California San Diego] Wearable ultrasound researchers have developed a stretchable ultrasonic array for serial, noninvasive, 3-D tissue imaging with a penetration depth of up to 4 cm. The latest device out of Sheng Xu’s lab at the University of California San Diego (UCSD) is able to frequently evaluate the stiffness of human tissue. It could be used to measure the progression of cancer, to monitor muscles, tendons and ligaments, and assess the effectiveness of liver and cardiovascular treatments. Xu is commercializing the technology through a UCSD spinoff called Softsonics. “We integrated an array of ultrasound elements into a soft elastomer matrix and used wavy serpentine stretchable electrodes to connect these elements, enabling the device to conform to human ...
In a recent study published in the SLEEP Journal, researchers explored the association between poor sleep and the excessive use of digital technology among adolescents after adjusting for familial factors and examining the influence of environmental and genetic factors on the association. Background Although many studies have reported that excessive use of digital technology among adolescents and young adults is linked to lower sleep quality, recent research indicates that in studies that used relevant control groups, the association was weaker or non-significant. This implied that a third unexplored factor, such as environmental or genetic influences, could be the underlying reason for these observed associations. Factors related to parental control and lack of boundaries resulting in inconsistent bedtimes and excessive use of technology could be impacting the quality of sleep. Digital technology is thought to impact sleep quality in various ways. Hyperarousal and the requirement to constantly ...
The percentage of adults who smoked cigarettes in the United States fell to a historic low last year, the US Centers for Disease Control and Prevention found. However, e-cigarettes are becoming even more popular. About 11% of adults told the CDC last year that they were current cigarette smokers, according to the latest preliminary data from the National Health Interview Survey, a biannual survey that provides general information about health-related topics. The survey includes responses from 27,000 people age 18 and older. In 2020 and 2021, about 12.5% of adults said they smoked cigarettes. This is a significant drop from when surveys like these started. Surveys of Americans in the 1940s found that about half of all adults said they smoked cigarettes. Rates began to decline in the 1960s, and more recently, in 2016, 15.5% of adults said they smoked cigarettes. Recent studies have shown some groups ...
A new machine-learning method could help us gauge the time of our internal body clock, helping us all make better health decisions, including when and how long to sleep. The research, which has been conducted by the University of Surrey and the University of Groningen, used a machine learning program to analyze metabolites in blood to predict the time of our internal circadian timing system. The study is published in the journal Proceedings of the National Academy of Sciences. To date the standard method to determine the timing of the circadian system is to measure the timing of our natural melatonin rhythm, specifically when we start producing melatonin, known as dim light melatonin onset (DLMO). Professor Debra Skene, co-author of the study from the University of Surrey, said, “After taking two blood samples from our participants, our method was able to predict the DLMO of individuals with an accuracy comparable ...
Five months after merging, manufacturers Kindeva Drug Delivery and Meridian Medical Technologies are expanding their capabilities in Missouri. In a $100 million investment over four years, Meridian plans to convert its newly purchased building in Bridgeton to increase production of drug-device combination products with added fill-finish capability, the companies said. Since adding 300 jobs since the start of 2022, Meridian now employs more than 900 people in the St. Louis area, the companies said. Financial incentives from state and local municipalities are helping this investment, which was announced in a press release that included quotes from seven different government officials. “Meridian brings a strong history of specific expertise to support critical manufacturing capabilities for complex products—addressing a manufacturing shortage we have seen increase over the last several years,” Milton Boyer, Meridian’s CEO who now heads up both companies, said in the release. Reference: https://www.manufacturingchemist.com/news/article_page/Meridian_set_for_100m_sterile_fill-finish_expansion_in_US/208133
Kerry Dooley Young April 05, 2023 US regulators may soon clear blood-based biomarker tests for colorectal cancer (CRC), expanding potential options for patients seeking more convenient forms of screening. Most recently, Guardant Health, Inc, announced the completion of its US premarket approval application for its Shield blood test to screen for CRC. Approval by the US Food and Drug Administration (FDA) would position Guardant to later secure Medicare coverage for its test. Rival companies, including CellMax Life, Freenome, and Exact Sciences, which already offers the stool-based Cologuard product, are pursuing similar paths in their development of blood tests for CRC. If these companies succeed, clinicians and patients could have a choice of several FDA-approved tests in a few years. “They’re coming, and they will be increasingly widely used,” said David A. Johnson, MD, professor of medicine and chief of gastroenterology at Eastern Virginia Medical School in Norfolk, ...
An “overwhelming” number of health experts and authorities support tightening border controls around nicotine vaping products, with many wanting an import ban on non-nicotine vaping products as well, Australia’s drugs regulator has told the government. On Thursday afternoon, the Therapeutic Goods Administration (TGA) published the almost 4,000 public submissions made in response to the government’s proposed vaping reforms, aimed at tackling rising youth vaping rates and a burgeoning black market. “All state and territory governments supported tightening border controls for nicotine vaping products, with most also supporting closing the personal importation scheme and requiring import permits,” the TGA summary said. Health professional bodies, public health associations, individual health professionals and university researchers “overwhelmingly supported tightening border controls,” the TGA said. “Many public health experts and bodies submitted that border controls should be also be placed on non-nicotine vaping products.” The importation of all vaping products should be banned “as soon ...
A cutting-edge surgical robot is to be installed at the Royal Papworth Hospital in Cambridge. The Versius technology mimics human arm joints but has up to four times more rotation than the human wrist. It will be used in thoracic surgery, which includes heart and lungs, in a first for the UK. The device should make the surgery less invasive, improve outcomes and speed up patients’ recovery times, the hospital said. Staff at the hospital are to undergo a full training programme, with the first treatment due to start this spring. The technology is a partnership between the Royal Papworth and Cambridge-based company CMR Surgical. The robot is smaller than previous examples and is portable so it can be used in different theatres and for different specialities, which could include transplantation. “Our vision is to provide tomorrow’s treatment to today’s patients,” said Tim ...
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