Search Results for “cardiovascular” – Page 6 – media

Semaglutide sold for $20.3 billion!

On November 6, Novo Nordisk released its third-quarter report for 2024. In the first nine months of this year, sales increased by 23% to 204.7 billion Danish kroner, of which sales of diabetes and obesity treatment drugs increased by 25% to 191.8 billion Danish kroner. The star product Semaglutide continued to advance by leaps and bounds, with sales of three brands (sugar-lowering injection Ozempic, sugar-lowering tablets Rybelsus, and weight-loss injection Wegovy) reaching 141.213 billion Danish kroner, or about 20.3 billion US dollars, in the first nine months of this year. Not long ago, Eli Lilly also announced its performance, among which the sales of two brands of GIPR/GLP-1R dual agonist Tirzepatide (Mounjaro, a hypoglycemic injection, and Zepbound, a weight loss injection) reached US$11.0284 billion in the first three quarters of this year. Specifically, Mounjaro’s sales revenue was US$8.010 billion, and Zepbound’s sales revenue was US$3.018 billion. Zepbound has been rapidly ...
- Source: drugdu
- 55
- November 9, 2024
6 innovative drugs expected to receive FDA approval in November

According to the expected target date of PDUFA, it is expected that in November, the US FDA will make regulatory decisions on the approval of six innovative drugs. This article will introduce these therapies. Active ingredient: Zenocutuzumab Indications: NRG1 positive non-small cell lung cancer (NSCLC) or pancreatic cancer Company Name: Merus Zenocutuzumab is a bispecific antibody targeting HER2 and HER3, which exhibits potential therapeutic efficacy against NRG1+cancer by uniquely binding to HER2 and effectively blocking the interaction between HER3 and NRG1 or NRG1 fusion protein. Preclinical studies have shown that zenocutuzumab can strongly inhibit the formation of HER2/HER3 heterodimers, thereby suppressing oncogenic signaling pathways, preventing tumor cell proliferation, and blocking tumor cell survival. Clinical studies have shown that it has anti-tumor activity in various types of NRG1+cancer. According to the mid-term data from the recently released Phase 1/2 clinical trial, zenocutuzumab has shown persistent efficacy in the treatment of advanced ...
- Source: drugdu
- 51
- November 7, 2024
Kejun Pharmaceuticals Completes B+ Round of Phased Financing

On October 31, Shanghai Kejun Pharmaceutical Technology Co., Ltd. (hereinafter referred to as “Kejun Pharmaceutical”) announced the completion of its B+ round of phased financing. This round of financing was led by Guoxin Innovation Equity, and other major investors included Aeon Group and Infinity Capital, and the original investor Honghai Capital also continued to make additional investments. Qidian Capital served as the financial advisor for this round of financing and will continue to provide financing services to Kejun Pharmaceutical in the future. Kejun Pharmaceutical stated that the funds raised from this financing will be used to accelerate the clinical development of CG-0255, a core product in the cardiovascular field. About Kejun Pharmaceutical Kejun Pharmaceutical was established in Zhangjiang, Shanghai in 2018, focusing on the treatment of cardiovascular and cerebrovascular diseases and antiviral diseases, and focusing on the research and development of small molecules and nucleic acid drugs. At present, Kejun ...
- Source: drugdu
- 52
- November 7, 2024
NMN can prevent physical decline and poor sleep

Walking speed reflects the vitality of the muscles, bones, nerves and cardiovascular system, so our walking speed can also predict our lifespan. After the age of 65, our walking speed gradually decreases, and eventually our daily life will be affected, greatly reducing our quality of life. Therefore, it is very important to keep muscles, bones, nerves and heart healthy through endurance and resistance training. Exercise may be the best way to prevent slow walking. However, poor sleep quality and low energy levels may prevent many people from sticking with exercise. In addition, poor sleep quality and fatigue may be the cause of low NAD+ levels. Recently, Japanese scientists published a research article titled “Ingestion of β-nicotinamide mononucleotide increased blood NAD levels, maintained walking speed, and improved sleep quality in older adults in a double-blind randomized, placebo-controlled study” in the journal “GeroScience”. The results showed that supplementing NMN can prevent physical ...
- Source: drugdu
- 56
- November 6, 2024
Johnson&Johnson announces latest personnel changes

Recently, Larry Jones, Global Vice President and Group Chief Information Officer of Medical Technology at Johnson&Johnson (NYSE: JNJ), will leave the world’s second-largest medical device manufacturer. He will retire from Johnson&Johnson’s medical device business. The details of when and when the official resignation will take place, or who will take over, are still unknown. 01. Retirement of Group Chief Information Officer Recently, Larry Jones announced that he will retire from Johnson&Johnson’s medical device business. When asked when he will officially resign or if someone will replace him, he said he will share more details when the information becomes public. Johnson&Johnson Medical Technology did not respond to further information requests. Jones is a goal oriented leader who achieves transformational change through key principles such as business process integration, agile methods, and next-generation technology solutions. He focuses on driving digital surgical connectivity solutions for Johnson&Johnson’s oncology, orthopedics, cardiovascular, and general surgery robots ...
- Source: drugdu
- 49
- November 5, 2024
Breaking news, Johnson & Johnson Medical Global Vice President resigns

Not long ago, Larry Jones, Global Vice President and Group Chief Information Officer of Johnson & Johnson MedTech, announced his decision to resign. On the LinkedIn platform, Jones recalled fondly: “Looking back on the 35 glorious years spent at Johnson & Johnson, my heart is filled with deep nostalgia for the extraordinary times we have gone through together.” During his tenure in Johnson & Johnson’s medical device department, Jones was particularly committed to promoting the company’s innovation in oncology, orthopedics, cardiovascular and general surgery, and realizing the innovation of digital surgical connection solutions through advanced technologies such as surgical robots and machine learning platforms. As a senior technology executive, Jones has rich leadership experience. During his decades in office, he has led many major projects in Johnson & Johnson’s pharmaceutical and medical device departments, including the recent three-year, $200 million global digital transformation plan. According to LinkedIn information, Jones is ...
- Source: drugdu
- 44
- November 5, 2024
Hengrui Medicine’s “2 Category 1 new drugs” approved for clinical trials

Recently, according to the official website of CDE, two Class 1 new drugs of Hengrui Medicine have obtained implicit approval for clinical trials, namely HRS-5632 injection and HRS-6208 capsule. The former is intended to treat lipoprotein disorders, and the latter targets solid tumors. Lipoprotein disorders Lipoprotein disorder refers to the abnormal metabolism of plasma lipoproteins. Studies have shown that it may lead to abnormal transport and distribution of lipids in the blood, thus causing a series of health problems. At present, lipoprotein disorder has been confirmed to be an independent risk factor for atherosclerotic cardiovascular disease (ASCVD), and there is no specific drug to treat it. It is reported that cardiovascular diseases, mainly ASCVD, are the leading cause of death among urban and rural residents in China, accounting for more than 45% of the causes of death. In response to lipoprotein disorder, Hengrui Medicine has deployed a small molecule drug ...
- Source: drugdu
- 56
- November 5, 2024
CPHI Middle East

Organiser：Informa Markets Time：December 10 – 12, 2024 Address：306-1-1-King Abdullah Rd, King Abdullah Dt., Riyadh 11564, Saudi Arabia Exhibition hall：Riyadh International Convention & Exhibition Center Product range: Active Pharmaceutical Ingredients (APIs): Vitamins, Hormones, Sulfonamides, Antipyretic and Analgesic Drugs, Tetracyclines, Amino Acids and Their Derivatives, Chloramphenicols, Digestive System Medications, Other Anti-infectives, Penicillins, Aminoglycosides, Lincomycins, Cardiovascular System Medications, Antiparasitic Drugs, Cephalosporins, Macrolides, Respiratory System Medications, Central Nervous System Medications, Other Pharmaceutical Raw Materials Pharmaceutical Machinery: Pharmaceutical Machinery, Packaging Machinery, Packaging Materials, Production Equipment and Technology for Pharmaceuticals, Pharmaceutical Packaging Equipment, Pharmaceutical Packaging Materials, Pharmaceutical Production, Cleaning, Sterilization Equipment, and Laboratory Instrument Systems Pharmaceutical Products: Various Proprietary Chinese Medicines, Western Medicines, New Drugs, Specialty Drugs, Various APIs, Chemical Pharmaceuticals, Pharmaceutical Intermediates, Biopharmaceuticals, Traditional Medicines, Chinese Herbal Medicines, Herbal Medicines, Plant and Animal Extracts, Veterinary Medicines, Food Ingredients and Additives, etc. About CPHI Middle East： CPHI Middle East, the Pharmaceutical Ingredients Exhibition in ...
- Source: drugdu
- 76
- October 31, 2024
“Plan B” for Chinese pharmaceutical companies to go overseas

Weighing the risks is the primary issue that all pharmaceutical companies need to consider when going overseas. The cost of going overseas is not cheap. Not to mention the time cost required to build overseas clinical, promotion, and registration experience, the capital cost is the top priority. BeiGene provides a good reference: although it has seen the dawn of profitability, this is based on the total loss of nearly 50 billion yuan in the past five years; Legend Biotech’s overseas cost is not low either. It is estimated that it has spent at least 1 billion US dollars since the establishment of the Xidaqiolunsai project. Industry insiders commented that this is far more expensive than imagined. From the perspective of capital investment alone, it can be asserted that there are not many pharmaceutical companies that can play the two cards of “local + going overseas” at the same time. To ...
- Source: drugdu
- 71
- October 30, 2024
Are stem cells the “terminator” of diabetes? Chinese scientists used stem cell regeneration therapy to cure type 1 diabetes for the first time

Cell, an international authoritative scientific journal, recently published a pioneering achievement from multiple research teams in China – the first time to use stem cell regeneration therapy to functionally cure type 1 diabetes. The research team used chemical reprogramming technology to induce pluripotent stem cells to prepare islet cells, and transplanted them to a type 1 diabetes patient, achieving clinical functional cure effect. So, how is it successful to induce stem cells to prepare pancreatic islet cells? Is functional cure truly a cure? Will stem cell technology be the key to conquer diabetes in the future? What is the difference between functional cure and cure Diabetes is a thorny disease, and its biggest harm to patients is that there are many clinical complications, which may lead to cardiovascular disease, nervous system damage, kidney disease, eye disease, foot disease, and so on. Diabetes ranks ninth among the world’s ten leading ...
- Source: drugdu
- 93
- October 28, 2024

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