July 12, Digene (Jiangsu) Pharmaceutical Co., Ltd. (hereinafter referred to as “Digene Pharmaceutical”) held a press conference in Beijing on the approval of Shuvozal® in the United States. Reporters learned that ZEGFROVY® (generic name: Suvotinib tablets) of Digene Pharmaceuticals has been included in the National Comprehensive Cancer Network (NCCN) non-small cell lung cancer guidelines for the treatment of previously treated epidermal growth factor receptor (EGFR) exon 20 insertion mutation (exon20ins) non-small cell lung cancer (NSCLC). ZEGFROVY® has become the only EGFR exon20ins NSCLC small molecule targeted drug in the world that has been included in the international authoritative lung cancer guidelines. Earlier, Shuwozhe® was approved for marketing by the U.S. Food and Drug Administration (FDA) through priority review on July 3, becoming the world’s first and only EGFRexon20ins NSCLC innovative drug approved in the United States.It is also China’s first independently developed global innovative . Professor Wang Mengzhao of Peking ...
On July 10, according to the official website of NMPA, Ascentage Pharma’s highly anticipated pipeline product, lisatoclase tablets (APG-2575), has been conditionally approved for marketing for adult chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) patients who have previously received at least one systemic treatment including a Bruton’s tyrosine kinase (BTK) inhibitor. You should know that before this, there was only one Bcl-2 inhibitor in the world – venetoclax. Since then, the research and development boom of Bcl-2 drugs can be said to have lasted for ten years. Now, it has finally borne fruit in the biotech company Ascentage Pharmaceuticals. A major target for crossing the cycle Bcl-2 is the founding member of the Bcl-2 regulatory protein family, the most notable feature of which is its regulatory role in mitochondrial apoptosis. The Bcl-2 family of proteins consists of members that promote or inhibit apoptosis, and controls apoptosis by controlling mitochondrial outer membrane ...
On July 9, Merck announced that it had reached a final agreement with Verona Pharma (VRNA), a biopharmaceutical company focusing on respiratory diseases. According to the agreement, Merck will acquire Verona’s American Depositary Shares (ADS) through a subsidiary at a price of US$107 per share, with a total transaction value of approximately US$10 billion. Through this acquisition, Merck will acquire Ohtuvayre, a first-in-class new COPD drug, expanding its R&D pipeline and product portfolio for the treatment of cardiopulmonary diseases, which is expected to drive growth over the next decade. This is not the first time Merck has made a big investment. According to public data, the patent for PD-1 inhibitor Keytruda, which accounts for nearly half of Merck’s revenue, is about to expire, and the US government is expected to negotiate for Keytruda under the IRA in 2026. Another best-selling drug of Merck, HPV vaccine Gardasil, is facing severe challenges ...
On July 13th, Chengyi Pharmaceutical (603811) released a performance forecast announcement for the first half of the year. In the first half of 2025, the company expects to achieve a net profit attributable to the parent company of 107 million to 119 million yuan, a year-on-year increase of 40% to 55%; It is expected to achieve a non recurring net profit of 106 million to 113 million yuan, a year-on-year increase of 47.4% to 57.4%. The main reasons for the expected increase in performance are stated in the announcement, on the one hand, the continuous growth of the company’s joint drug sales, and on the other hand, the reduction of losses by the subsidiary in the previous year. The joint drug glucosamine hydrochloride capsules (hereinafter referred to as “glucosamine”) are the company’s main products and one of the main driving forces for performance growth in the first half of the ...
On the evening of July 13th, Kanghua Biotechnology (300841) announced that its controlling shareholder and actual controller, Wang Zhentao, is planning to change the company’s control rights, which may lead to a change in the company’s controlling shareholder and actual controller. Upon application to the Shenzhen Stock Exchange, the company’s stock will be suspended from trading starting from Monday, July 14th, with an expected suspension period of no more than 2 trading days. It should be noted that before the suspension, Kanghua Biotechnology saw a significant increase in trading volume on July 11th, with the latest stock price reaching 72.01 yuan per share. According to the data, Kanghua Biotechnology is mainly engaged in the research and development, production, and sales of human vaccines. The company has obtained drug registration certificates for vaccines such as freeze-dried human rabies vaccine (human diploid cell) and ACYW135 meningococcal polysaccharide vaccine. Kanghua Biotechnology’s net profit ...
Although many of your patients may think that increasing protein is the key to fat loss and successful weight management, there’s a consensus in the medical community that patients should be aware that there can, indeed, be too much of a good thing. “I feel like protein intake, although important, is grossly overemphasized in weight loss, and a strong focus on protein can miss other critical goals necessary for weight loss — chief among them [being] caloric restriction but also fiber intake and adequate nutrients,” said Matthew Badgett, MD, internal medicine physician at Cleveland Clinic in Ohio. “I discuss protein but advise to not overdo it.” While protein is one of the key macronutrients our bodies need to build muscle and repair tissue, patients should know of varying sources. “Lean proteins are a great option and can come from both animal and plant-based sources like lentils, peas, and other high-protein ...
Exposure to endocrine-disrupting chemicals in early life, including during gestation and infancy, results in a higher preference for sugary and fatty foods later in life, according to an animal study being presented Sunday at ENDO 2025, the Endocrine Society’s annual meeting in San Francisco, Calif. Endocrine-disrupting chemicals are substances in the environment (air, soil or water supply), food sources, personal care products and manufactured products that interfere with the normal function of the body’s endocrine system. To determine if early-life exposure to these chemicals affects eating behaviors and preferences, researchers from the University of Texas at Austin conducted a study of 15 male and 15 female rats exposed to a common mixture of these chemicals during gestation or infancy. “Our research indicates that endocrine-disrupting chemicals can physically alter the brain’s pathways that control reward preference and eating behavior. These results may partially explain increasing rates of obesity around the world,” ...
Organiser: Nanchang Municipal People’s Government, Chinese Research Hospital Association Time:August 21–23, 2025 address:No. 1315 Huaiyushan Avenue, Honggutan New District, Nanchang City Exhibition hall:Nanchang Greenland International Expo Center Product range: Cardio-cerebrovascular Monitoring Equipment: EEG machines, EMG machines, ECG machines, evoked potential devices, remote monitoring systems, HOLTER monitors, defibrillator monitors, exercise treadmill ECG systems, ambulatory blood pressure monitors, oximeters, and auxiliary diagnostic devices. Medical Materials and Supplies: Various medical consumables, enamel and glassware, dressing rubber products, disposable items, reagents, clinical laboratory equipment, and blood transfusion supplies. Clinical Laboratory Equipment: Medical incubators, centrifuges, microscopes, pre-analytical processing equipment, and body fluid handling devices. Biochemical Analysis Instruments: Automatic biochemical analyzers, hematology analyzers, hemodialysis machines, blood gas analyzers, microbiology analyzers, urinalysis analyzers, flow cytometers, electrolyte analyzers, ELISA readers, chromatographs, PCR machines, DNA synthesizers, laboratory instruments, apparatus, and supplies. Blood Transfusion Equipment: Blood testing devices, refrigeration equipment, blood collection and supply instruments, blood bank equipment, blood bank ...
A new allergy medication is prompting clinicians to adjust their approach to oral food challenges — medically supervised tests in which clinicians give increasing doses of an allergen like peanut or milk to see how a patient reacts. The FDA in 2024 approved omalizumab (Xolair) to help reduce allergic reactions in adults and children aged 1 year or older with immunoglobulin E-mediated food allergy. Patients receiving the injections are supposed to avoid foods to which they are allergic. In the event of an accidental exposure, the medication can afford protection against a serious reaction. The approval opened a new frontier in allergy therapy but also raised questions without clear answers, like: How can patients be sure the medication is working? And how will they know if they “outgrow” an allergy, as some people do? After the approval, clinicians wrote to the American Academy of Allergy, Asthma & Immunology seeking advice. ...
Adcentrx Therapeutics, a clinical-stage biotechnology company developing antibody-drug conjugate (ADC) therapies for cancer treatments and other life-threatening diseases, announced on July 8, 2025, that FDA has granted orphan drug designation to ADRX-0405, Adcentrx’s treatment of patients with gastric cancer. “Receiving orphan drug designation from FDA is a notable milestone for Adcentrx and reinforces the potential for ADRX-0405 to improve the lives of patients with gastric cancer,” said Hui Li, Ph.D., founder and chief executive officer of Adcentrx. “We are encouraged by the progress of our Phase 1a trial and look forward to further evaluating the safety, tolerability and anti-tumor activity of ADRX-0405 in gastric and other cancer.”1 ADRX-0405 is currently under evaluation in Phase 1a of Phase 1a/b clinical trials for treatment of select advanced solid tumors such as metastatic castration resistant prostate cancer, gastric cancer, and non-small cell lung cancer. This is a 2-part study. Phase 1a will consist ...
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