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Celgene Corporation and bluebird bio Announce bb2121 Anti-BCMA CAR-T Cell Therapy Has Been Granted Breakthrough Therapy Designation

Celgene Corporation and bluebird bio, Inc. announced that bb2121, a chimeric antigen receptor T-cell (CAR-T) therapy targeting b-cell maturation antigen (BCMA) in previously treated patients with multiple myeloma, has been granted Breakthrough Therapy Designation (BTD) by the U.S. Food and Drug Administration (FDA) and PRIority MEdicines (PRIME) eligibility by the European Medicines Agency (EMA).
- Source: ansa.it
- 597
- November 17, 2017
BTD CAR-T therapy Company Insight
Sangamo Announces Treatment of First Patient in Landmark Phase 1/2 Clinical Trial Evaluating In Vivo Genome Editing for MPS II

Sangamo Therapeutics, Inc. (SGMO) today announced treatment of the first patient in the Phase 1/2 clinical trial ("the CHAMPIONS study") evaluating SB-913, an investigational in vivo genome editing therapy for people with mucopolysaccharidosis type II (MPS II), also known as Hunter syndrome.
- Source: finance.yahoo
- 423
- November 17, 2017
Company Insight Hunter syndrome MPS II
Salt raises blood pressure, but our gut bacteria can stop it

It's a known fact that too much salt can increase blood pressure. But new research brings gut bacteria into the mix, and some good news along with it: probiotics may help to reverse the harmful effects of excessive salt.
- Source: medicalnewstoday
- 717
- November 17, 2017
blood pressure cardiovascular gut bacteria New Approvals
FDA approves new drug to treat bleeding in hemophilia A patients

The U.S. Food and Drug Administration(FDA) today approved Hemlibra (emicizumab-kxwh) to prevent or reduce the frequency of bleeding episodes in adult and pediatric patients with hemophilia A who have developed antibodies called Factor VIII (FVIII) inhibitors.
- Source: news-medical
- 643
- November 17, 2017
FDA Hemlibra inhibitor pediatric
Using social media big data to combat prescription drug crisis

Their study found that with proper research methods and attention to privacy and ethical issues, social media big data can reveal important information concerning drug abuse, such as user-reported side effects, drug cravings, emotional states, and risky behaviors.
- Source: drugdu
- 579
- November 17, 2017
prescription drug abuse
Jardiance is the first and only oral type 2 diabetes medicine approved to reduce the risk of cardiovascular death in adults with type 2 diabetes and established cardiovascular disease.

New data presented today showed that Jardiance® reduced the risk of cardiovascular death compared with placebo when added to standard of care in adults with type 2 diabetes and peripheral artery disease.
- Source: finance.yahoo
- 613
- November 17, 2017
cardiovascular diabetes Jardiance® peripheral artery disease
How common are flu shot side effects?

With fall well underway and winter just around the corner, chances are your doctor, pharmacist, and maybe even your mom are telling you it's time to roll up your sleeve for a flu shot. If you're inclined to ignore them, we get it: No one really enjoys being jabbed with a needle.
- Source: foxnews
- 512
- November 17, 2017
flu shot
FDA Clears First Device to Help Curb Opioid Cravings

The US Food and Drug Administration (FDA) has approved a device designed to reduce the symptoms of opioid withdrawal.
- Source: medscape
- 588
- November 16, 2017
cranial nerves FDA New Approvals opioid stimulator
Medical first-Doctors attempt to gene-edit a living patient’s DNA

A man may soon be forever free of the previously incurable disease he was born with 44 years ago. On Monday, in a medical first, Brian Madeux received an experimental in-body gene-editing treatment intended to cure him of Mucopolysaccharidoses II, known as MPS II or Hunter syndrome, a rare disorder that causes progressive damage to the body's cells.
- Source: flipboard
- 437
- November 16, 2017
enzyme Hunter syndrome Market Views mucopolysaccharides
New dye gives scientists a clearer insight into the brain

Keele University researchers have designed a new dye that can be used to observe the electrical activity of neurons in the brain and could lead to finding a new and more efficient way of treating neurological diseases, as presented at the Society for Neuroscience annual conference in Washington, D.C. this week.
- Source: sciencedaily
- 419
- November 16, 2017
neurological Researches

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