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Merger of two well-known pharmaceutical companies

On October 7, Jiahe Bio announced that it would acquire Yitong Pharmaceuticals by merger. The name of the merged company will be changed to Yitong Jiahe Pharmaceutical Group Co., Ltd. (hereinafter referred to as “Yitong Jiahe”). The transaction is carried out in the form of a share swap. The price of the proposed merger will be fully settled by issuing consideration shares. After the merger is completed, the shareholders of both parties will jointly hold the equity of Yitong Jiahe, and Jiahe Bio will not have any cash expenditure. According to the listing rules, the transaction constitutes a reverse acquisition of Jiahe Bio. In the merged Yitong Jiahe, the original Yitong Pharmaceutical shareholders accounted for 77.43%, and the original Jiahe Bio shareholders accounted for 22.57%. The actual controller of Yitong Pharmaceutical will become the controlling shareholder of Yitong Jiahe. Based on the rules of Chapter 18A of the Hong Kong ...
- Source: drugdu
- 70
- October 10, 2024
The 2024 “Most Promising New Talent in Biopharmaceuticals” list has been released!

Recently, well-known industry media Endpoint News released the “Biopharma’s Most Exciting Startups in 2024” list, which includes 11 biotechnology companies. These emerging research fields include gene editing, immunotherapy, antibody conjugated drugs (ADCs), weight loss therapy, and multiple other directions. This article will introduce these 11 rising stars (listed in no particular order) to readers, based on this ranking and official information from various companies. Lifordi Immunotherapies is a biotechnology company dedicated to developing ADC therapies for the treatment of autoimmune and inflammatory diseases. Lifordi was founded in 2023 and has secured $70 million in Series A funding from ARCH Venture Partners, 5AM Ventures, and Atlas Venture, with the goal of advancing the main candidate drug LFD-200 into clinical trials and obtaining preliminary data by the end of 2025. Lifordi’s main ADC therapy LFD-200 targets myeloid cells and lymphocytes by targeting highly internalized cell surface facial mask proteins. This therapy has ...
- Source: drugdu
- 94
- October 9, 2024
sell right, sell well, and sell for a long time

First, the essence of business is market competition, and the market is the battlefield. Business people should have a sales mindset, and salespeople need to have a business perspective. There is a view that sales and business are different positions in pharmaceutical companies, with different responsibilities and assessment standards, and it is difficult to integrate the two positions, so you can focus on your own duties. However, the performance appraisal of most pharmaceutical companies is still stuck in the “butt determines the head” standard, and there is rarely a global vision of “the head decides the butt”. It is beneficial for sales and business to empathize, but it cannot completely resolve all conflicts and disputes. At the time of the transformation of the pharmaceutical industry, cross-disciplinary talents who are both proficient in sales and business are increasingly becoming valuable resources for enterprises to compete for. The business position in the ...
- Source: drugdu
- 86
- October 5, 2024
Digital therapeutics are a big failure

The digital therapeutics industry has evolved and evolved beyond all expectations. In June 2021, Pear Therapeutics, the “first stock of digital therapeutics”, was listed; In April 2023, he filed for bankruptcy and bankruptcy; A year later, Better Therapeutics, another star digital therapeutics company, also fell; Four months ago, Akili chose to sell himself and delist and go private. So far, the three musketeers of overseas digital therapeutics have all fallen. If you count from the listing of Pear, a three-year cycle, the waves will sweep away the heroes. On the surface, the main reason for the collapse of these companies is financial problems, but the deeper reason is the commercialization challenges faced by digital therapeutics. The challenge is that digital therapeutics need to have drug-like efficacy in order to gain market acceptance, but the embarrassment is that prescription digital therapeutics are not drugs per se, but more about using technical ...
- Source: drugdu
- 66
- October 5, 2024
Over 3 billion, Stone Pharmaceutical Group reached a major cooperation

On September 29, Shi Pharma Group signed an exclusive licensing agreement with Jiangsu Conri Pharma on the development and commercialization of JSKN003 in mainland China. JSKN003 is a HER2-targeting bispecific antibody-drug conjugate (ADC) with dual HER2 targeting, giving it stronger internalization induction and bystander killing effects, making it highly active against HER2-expressing tumors. Currently, JSKN003 is undergoing Phase I clinical trials in Australia and Phase I/II and Phase III clinical trials in China. Next, Jinmant Bio (a wholly-owned subsidiary of Chiatai Tianqing Pharmaceutical Group) will be granted exclusive license and sublicensing rights for the development, sales, promised sales, and commercialization of the product. They will bear all clinical development costs and become the sole marketing authorization holder for JSKN003 in Mainland China for that field. According to the agreement, Corning Jerry has the right to receive a total of up to 3.08 billion RMB in upfront and milestone payments, including ...
- Source: https://mp.weixin.qq.com
- 98
- October 2, 2024
Global Leader! Qilu Pharmaceutical’s ATO Combination Antibody Approved for Second-line Treatment of Cervical Cancer

Recently, the combination antibody of apalutamide toripalimab (QL1706, trade name: Qilu’an, hereinafter referred to as “etuo combination antibody”) has been approved by the National Medical Products Administration (NMPA) of China for the treatment of recurrent or metastatic (R/M) cervical cancer patients who have failed platinum-based therapy. This milestone development not only signifies a major breakthrough in the treatment of advanced cervical cancer in China, but also heralds a new stage of development for cancer immunotherapy.It is reported that the Etu combination antibody is the first dual-function combination antibody targeting PD-1 and CTLA-4 designed and produced by Qilu Pharmaceutical through its self-developed MabPair®️ technology platform. It has shown great potential in the treatment of solid tumors such as cervical cancer, lung cancer, and liver cancer, demonstrating both efficacy and safety. With its unique mechanism, it is at the forefront of the journey of tumor dual immunotherapy strategy!Cervical cancer is the ...
- Source: https://mp.weixin.qq.com
- 101
- October 2, 2024
What Are Its Treatment Prospects?

Recently, according to publicly available information from the Center for Drug Evaluation (CDE) of the National Medical Products Administration, the technetium-99m ([99mTc]) hydrazinonicotinamide polyethylene glycol RGD peptide injection (referred to as “99mTc-3PRGD2”) developed by Ruidiao Pharmaceuticals has been included in the priority review list. This also applies to the injection of toluenesulfonate hydrazone nicotinamide polyethylene glycol RGD peptide. 99mTc-3PRGD2 is a radiolabeled drug conjugate (RDC) independently developed by Ruidiao Pharmaceuticals. It is the first class I new drug for radiologic diagnosis in nuclear medicine in China and the world’s first broad-spectrum tumor imaging agent for SPECT imaging. Notably, the success of this drug’s development will change the current technical status and conventional understanding that SPECT/CT imaging technology in nuclear medicine cannot be used for tumor diagnosis, staging, and efficacy evaluation. According to Ruidiao Pharmaceuticals, 99mTc-3PRGD2 targets integrin and specifically binds to the integrin αvβ3 receptor on tumor neovascularization, demonstrating high ...
- Source: drugdu
- 83
- September 30, 2024
From the rise of Sinocell, we can see the first principles of pharmaceutical companies

In the 1950s, George W. Merck, then CEO of Merck, said a widely circulated saying in the pharmaceutical industry: “We should always remember that drugs are produced for humans, not for the pursuit of profits. As long as we stick to this belief, profits will follow.” It is true. Looking at large overseas pharmaceutical companies, the key to their success lies in patient-centeredness and a strong sense of social responsibility. In China, there are more and more such examples. For example, the vision of Sinocell is to focus on the research and development of drugs urgently needed by the people and provide patients with high-quality and affordable biological drugs. It seems to coincide with Merck. On the product side, Sinocell uses technological innovation to provide higher quality and lower cost drugs, which reduces the economic burden of domestic patients, while bringing better treatment effects and achieving a win-win situation of ...
- Source: drugdu
- 78
- September 30, 2024
Pfizer and Shanghai Pharmaceuticals Reach Strategic Cooperation to Create High-Quality Preventive Immunization Services

On September 26, Pfizer Investment Co., Ltd. (referred to as Pfizer) and Shanghai Pharmaceuticals Holding Co., Ltd. (referred to as Shanghai Pharmaceuticals) signed a strategic cooperation framework agreement. The two parties will focus on the vaccine field, engaging in long-term collaboration in product promotion, the introduction of innovative products, and policy research. Leveraging their respective strengths, they will explore strategies to deepen and enhance their partnership in the commercial promotion of vaccine products and accelerate the introduction of innovative products, along with thorough cooperation in policy research and capacity training. This effort aims to support the robust development of China’s public health services and disease control efforts, ultimately aiding disease prevention and health improvement across all stages of life. Jean-Christophe Pointeau, President of Pfizer China, stated: “The collaboration between Pfizer and Shanghai Pharmaceuticals will harness both parties’ strengths to empower the promotion and dissemination of innovative vaccines scientifically, allowing internationally ...
- Source: drugdu
- 79
- September 29, 2024
CT angiography image assisted detection software for intracranial aneurysms approved for market launch

On September 25th, the National Medical Products Administration announced that it has recently approved the registration application for the innovative product “CT angiography image assisted detection software for intracranial aneurysms” of Shanghai Lianying Intelligent Medical Technology Co., Ltd. (hereinafter referred to as “Lianying Intelligent”). Effective improvement, innovative products begin to emerge Lianying Intelligence is an artificial intelligence company under Lianying Group, established in Shanghai at the end of 2017. It is an important strategic layout of Lianying Group in the field of artificial intelligence. Relying on the high-performance software and hardware technology platform and resource advantages of Lianying Group, Lianying Intelligence has become a medical AI enterprise that can provide multi scenario, multi disease, full process, and integrated intelligent solutions. It empowers clinical, scientific research, and equipment with AI, covering multiple AI application scenarios such as hospital level management, medical innovation ecology, workflow optimization, precision diagnosis and treatment, and personal ...
- Source: drugdu
- 72
- September 28, 2024

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