Researchers from University of California San Diego have found a way to distinguish among hand gestures that people are making by examining only data from noninvasive brain imaging, without information from the hands themselves. The results are an early step in developing a non-invasive brain-computer interface that may one day allow patients with paralysis, amputated limbs or other physical challenges to use their mind to control a device that assists with everyday tasks. The research, recently published online ahead of print in the journal Cerebral Cortex, represents the best results thus far in distinguishing single-hand gestures using a completely noninvasive technique, in this case, magnetoencephalography (MEG). “Our goal was to bypass invasive components,” said the paper’s senior author Mingxiong Huang, PhD, co-director of the MEG Center at the Qualcomm Institute at UC San Diego. Huang is also affiliated with the Department of Electrical and Computer Engineering at the UC San ...
Life Biosciences has announced a cGMP manufacturing collaboration with Forge Biologics for advancing the development of new gene therapies to treat aging-related diseases. This partnership aims to help advance the company’s partial epigenetic reprogramming platform for aging-related diseases, such as its lead programme that targets the ophthalmic indications. Through the alliance, Forge Biologics will provide cGMP manufacturing, toxicology, adeno-associated virus (AAV) process development, and analytical services to Life Biosciences. Life Biosciences will use the platform processes of Forge Biologics, including the HEK293 suspension Ignition Cells and per adenovirus helper plasmid. The company stated that all the development and AAV manufacturing works will take place at Forge Biologics’ 200,000ft2 gene therapy facility, called Hearth, located in Columbus, Ohio, US. Life Biosciences CEO Jerry McLaughlin said: “We are delighted to be working with the Forge team, whose expertise in gene therapy manufacturing is unmatched. “We believe we’re on the cusp of revolutionising ...
In the majority of cases, graft failure after heart transplantation is attributable to abnormalities like severe coronary artery disease. As donors with extended criteria like advanced age and pre-existing heart conditions become eligible for heart transplantation, careful screening for congenital abnormalities has become crucial. Invasive coronary angiography is an essential screening tool that can detect coronary artery disease (CAD), a condition characterized by cholesterol deposits in the heart’s arteries. However, logistical challenges limit utility so it’s used for fewer than a third of donors who are at risk of developing CAD. To overcome this limitation, a new heart preservation procedure called “ex situ heart perfusion” (ESHP) has been developed. By allowing the supply of oxygenated nutrients to the heart via blood vessels, ESHP allows doctors to monitor the performance of the heart and screen it for any defects outside the body. However, coronary angiography conducted during ESHP is known to damage ...
by Howard Hughes Medical Institute Overview of GCaMP calcium indictors for neuronal imaging. When they sense calcium, GCaMP indicators cause neurons to produce green fluorescent light, allowing scientists to see which neurons and synapses are activated in living animals as they perform a task. Credit: Yan Zhang New ultra-fast sensors developed at Janelia can detect calcium ions nearly as fast as they are released from neurons, allowing scientists to tease out the individual, milliseconds-long signals passing between brain cells. Genetically encoded calcium indicators dubbed GCaMPs are used to track the activity of large populations of neurons in living animals by revealing the calcium ions that are released as signals pass between neurons. When they sense calcium, GCaMP indicators cause the neurons to produce green fluorescent light, allowing scientists to see which neurons and synapses are activated in living animals as they perform a task. GCaMP indicators have become brighter and more sensitive since ...
Fujifilm Corporation’s planned $1.63 billion acquisition of Hitachi’s diagnostic imaging business has been put on hold in the midst of the ongoing COVID-19 pandemic. The Japanese healthcare giants, which began discussing the deal back in December, were aiming to complete the acquisition some time in July. Fujifilm, however, now says that “delays in some of the preparations” brought on by the spread of the virus have changed the completion schedule and that both parties will need more time to hammer out and finalize the details. “Due to the spread of CIVD19 globally, preparations for regulatory laws related to matters and clearance for anti-monopoly have been delayed. Government offices, legal offices and others impacted by lock downs and stay at home measures have slowed these activities,” Dave Wilson, director of communications for Hitachi Healthcare Americas, told HCB News. Fujifilm has delayed a planned acquisition of Hitachi’s diagnostic imaging-related business due to the ...
Aging is caused by the deterioration of various cellular organelles and physiological processes. The pathways elements that are affected during ageing include insulin resistance, changes in body composition, decline in growth hormone, insulin-like growth factor, and sex steroids.
The main function of the medical imaging equipment such as CT scanner is literally by adopting the radiographic techniques. The organs inside our bodies are covered by flesh and skin, which means we can’t inspect them directly through our eyes. In this kind of circumstance, the physician could use the medical imaging equipment to acquire the inside information without an invasive action. CT scanner as one of the most common medical imaging equipment, which could produce thin cross-sectional views of the human body. In the meanwhile, the CT scanner also could reconstruct the tomographic plane of the patient by using a number of imaged slices. The images given by the CT scanner are usually used for diagnostic purposes or any anatomic region if necessary. If you decided to make a CT scanner purchasing, tips below should be noticed. Affirming the specific type of CT scanner which could match your requirement, ...
A study published in the September issue of The Journal of Nuclear Medicine remarked that it noticed a huge drawback in the Prostate-specific membrane antigen (PSMA) positron emission tomography (PET) imaging technique and warned doctors who use only PSMA PET for diagnosis to be vigilant for faulty diagnosis. “It is important that nuclear medicine physicians be aware of this pitfall, as the interpretation of PSMA PET scans may have a substantial impact on therapy guidance,” said Christoph Rischpler, MD, in the department of nuclear medicine at the Technical University of Munich in Germany. For detecting prostate cancer staging and metastases in imaging, PSMA proves to be a very efficient target as it is an extremely easy-to-read enzyme, helping better diagnosis and plotting of management protocol. Recent findings, however, show that PSMA elevates in response to some benign tissue as well, duplicating findings of lymph node metastases. This could lead to ...
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Quick diagnosis and treatment monitoring are critical due to the emergence of multidrug resistance, especially in tuberculosis. Taking this fact into consideration, a research team from Stanford University School of Medicine developed an imaging technique to diagnose tuberculosis (TB) within an hour and monitor the effectiveness of treatments.
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