media – Page 282 – DrugDu- Global Leading Pharmaceutical & Medical Device Platform

ICR and Merck renew strategic alliance for development of new cancer drugs

The Institute of Cancer Research (ICR) and Merck KGaA have announced a renewal of their strategic alliance to discover and develop new small-molecule cancer drugs. Throughout the multi-year, multi-target collaboration, both organisations will contribute their expertise in drug discovery to the partnership. As part of the agreement, significant financial and staff commitments from both organisations will be made, including the funding of nine full-time research posts at the ICR by Merck. Scientists at the ICR’s Centre for Cancer Drug Discovery will cooperate with researchers at German science and technology company Merck on a variety of projects that aim to discover and develop new small-molecule inhibitors of a new class of cancer targets. In 2021, the ICR opened a new building worth £70m as part of its site in Sutton, South London, which houses around 300 scientists working across a range of disciplines in cancer drug discovery. Earlier this month, ICR ...
- Source: drugdu
- 105
- October 4, 2023
Glenmark solves its ‘decade-long’ debt problem with $681M sale of API unit to Nirma

By divesting 75% of its active pharmaceutical ingredient (API) business, Glenmark Pharmaceuticals has finally resolved its debt problem, described by an Indian news outlet as a “decade-long troubled affair.”The buyer is Nirma Limited, which will pay 615 Indian rupees per share, which comes to Rs 5,651 crore ($681 million) in total. Based in Ahmedabad, Nirma specializes in cosmetics, detergents, salt and injectables. In a press conference, Glenmark’s chairman and managing director Glenn Saldanha said the company was facing a gross debut of approximately Rs 4,600 crore ($555 million). “The total debt gets extinguished after the deal,” he added. In revealing (PDF) the sale, Glenmark said the deal allows it to become an innovative and brand-led company, focusing on its core therapeutic areas of dermatology, respiratory and oncology. The sale leaves the company with a 7.8% share in the API subsidiary, named Glenmark Life Sciences, which will continue to operate as ...
- Source: drugdu
- 148
- October 4, 2023
Seagen and Astellas’ Padcev, in Keytruda combo, delivers ‘practice-changing’ bladder cancer win

As Seagen prepares for its takeover by Pfizer, the company’s Astellas-partnered cancer drug Padcev has chalked up a key trial win—in combination with Merck’s Keytruda—in previously untreated metastatic bladder cancer. In the study, Seagen and Astellas’ antibody-drug conjugate Padcev and Merck’s PD-1 superstar Keytruda scored on both overall survival and progression-free survival compared with chemotherapy. An independent data monitoring committee found that the combo’s life extension benefit surpassed the pre-specified efficacy boundary at an interim analysis, the companies said in a Friday release. The results could open the combo up to patients who are eligible for platinum-based chemotherapies cisplatin or carboplatin, regardless of their PD-L1 status. “This study has the potential to be practice changing and offer a new standard of care for first-line metastatic bladder cancer,” Seagen’s R&D head Roger Dansey, M.D., said in the release. “We look forward to presenting the results at an upcoming medical conference and ...
- Source: drugdu
- 110
- October 4, 2023
Socioeconomic status may not clearly predict the heart health of racial and ethnic groups

Improvements in socioeconomic status (education, income, employment status and health insurance) on ideal cardiovascular health may not benefit people from all racial or ethnic groups equally, as white adults were more likely to benefit than Black, Hispanic and Asian adults in the U.S., according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association. Joshua J. Joseph (M.D., M.P.H., FAHA, senior study author, associate professor of internal medicine, The Ohio State University College of Medicine in Columbus) said, “The goal of economic interventions and societal policies, such as improving employment, health care access and education, is that they will lead to improvements in health for everyone. However, our study found that improvements in these socioeconomic interventions may not benefit people in all racial or ethnic groups equally.” The researchers suggest that additional factors including psychosocial stress experienced ...
- Source: drugdu
- 249
- October 3, 2023
Study highlights the importance of support for caregivers in optimizing child behavior outcomes

Emotional support and tangible aid for caregivers benefited all families during the COVID-19 pandemic, not just those facing higher stress levels, according to a study funded by the Environmental influences on Child Health Outcomes (ECHO) Program at the National Institutes of Health. During the COVID-19 pandemic, many families experienced social isolation, economic hardship, and disruptions in daily routines. Communities of color suffered higher infection rates and greater financial hardship and disruption. ECHO researchers wanted to learn how these stressors on caregivers affected their children. Researchers looked separately at a subset of Black participants, who likely experienced unique discrimination during the pandemic. They found caregiver experiences of discrimination strengthened the relationship between COVID-19 pandemic stress and child behavior problems, specifically those related to anxiety and depression. The study found that higher levels of support for caregivers were associated with fewer behavior problems overall. On the other hand, higher amounts of stress ...
- Source: drugdu
- 132
- October 3, 2023
Developer of miniaturized surgical robot extends funding round

Dive Brief Virtual Incision, the startup that is getting ready to send a tiny surgical robot into space, said it has raised $30 million in an extension of its previous $46 million series C financing. The funding round will support the company’s operations “well into 2025” as it prepares to commercialize the compact robotic system designed for abdominal surgery, Virtual Incision said. The Lincoln, Nebraska-based company in May submitted a de novo request to the Food and Drug Administration to market the robot for use in bowel resection procedures, after completing an investigational device exemption study. Dive Insight A modified version of Virtual Incision’s MIRA system is headed to the International Space Station in 2024 on a test mission to perform simulated surgical tasks, in a collaboration between NASA and the University of Nebraska-Lincoln. The goal is to pave the way for performing telesurgery in space, according to the company. ...
- Source: drugdu
- 206
- October 3, 2023
Should More Doctors Be on TikTok? This One Says Yes

Gastroenterologist Dr. Austin Chiang has about a decade of experience as a physician influencer on social media. During a conference in Chicago, he encouraged more providers to share their expertise on social media. By having a presence on these platforms, healthcare professionals demonstrate their commitment to meeting patients where they are, he said. By KATIE ADAMS As a gastroenterologist, Dr. Austin Chiang has witnessed plenty of patients get admitted to the hospital after taking unvetted medical advice they found on the Internet, he said Wednesday during an interview at Oliver Wyman’s Health Innovation Summit in Chicago. About 10 years ago, Dr. Chiang took to social media to address this issue by being a credible source for health information. At the time, many of his colleagues thought this was a waste of time — but he has since proved them wrong. He now has nearly 750,000 followers across his TikTok, YouTube, ...
- Source: drugdu
- 227
- October 3, 2023
Study could pave the way to new treatments for people with compromised immune systems

New research led by Queen’s University Belfast has made a breakthrough in the field of microbiology, which could lead to the development of new treatments for people with compromised immune systems, such as those with cystic fibrosis. To conduct their study the researchers looked at the bacterium Achromobacter which can cause chronic lung infection and tissue damage in the airways. The study reveals how this bacterium overcomes the body’s immune defenses to multiply and continue to grow. The findings have been published in Cell Reports. Professor Miguel A. Valvano, Chair in Microbiology and Infectious Diseases at the Wellcome-Wolfson Institute for Experimental Medicine (WWIEM) at Queen’s University Belfast and lead researcher on the study, explains: “Achromobacter bacteria can cause chronic and potentially severe infections. However, until now, how this opportunistic bacterium interacts with the human immune system has been poorly understood. “These bacteria resist the action of multiple antibiotics; therefore, infection ...
- Source: drugdu
- 238
- October 3, 2023
Ariceum doses first patient with satoreotide

by John Pinching The treatment targets extensive stage small cell lung cancer and aims to boost therapeutic impact Ariceum Therapeutics, a company developing products for the treatment of specific cancers, has announced that the first patient has been dosed with its satoreotide therapy. The treatment targets extensive stage small cell lung cancer (ES-SCLC), while the research is taking place at the Murdoch University Health Center in Australia. Ariceum’s broader open label phase 1b trial will analyse the tolerability and safety of the ‘theranostic pair’ of somatostatin receptor antagonists, ga-satoreotide trizoxetan and lu-satoreotide tetraxetan, among patients with ES-SCLC. The central aim of the research is to establish a recommended phase 2 dose and schedule in due course. ‘Theranostics’ is the system of incorporating two paired drugs: the first, a diagnostic agent to identify cells that exhibit a particular biomarker, and the second, a therapeutic drug which subsequently acts on those cells. ...
- Source: drugdu
- 206
- October 3, 2023
Weight Loss Drugs Will Have Impact Far Beyond Just On Drugmakers

GLP-1s — which lower blood sugar to help people lose weight — are taking the healthcare industry by storm and have several implications for digital health companies. This includes headwinds for established nutrition programs and the potential for the launch of new virtual weight loss startups, according to a PitchBook report published Friday. The PitchBook authors believe that because of the prevalence of obesity in the U.S., the impact of GLP-1s “will extend far beyond the drugmakers themselves.” So far, four GLP-1 agonists have FDA approval: Ozempic, Rybelsus, Wegovy and Mounjaro. Wegovy, however, is the only one indicated for weight loss, while the others are indicated for Type 2 diabetes. PitchBook listed the potential effect of weight loss drugs on several specific VC-backed digital health companies. For example, Ro and Noom may see new customers through their weight loss telehealth offerings. Form Health could see a rising adoption of their ...
- Source: https://medcitynews.com/2023/10/weight-loss-drugs-glp1s-digital-health/
- 224
- October 3, 2023

your submission has already been received.

OK

Subscribe

Please enter a valid Email address！

Submit

The most relevant industry news & insight will be sent to you every two weeks.

more

more

Customer Services
Contact Us
Help Center

Buy on Drugdu.com
Browse Product Categories

Free APP

Follow Us

Terms & Conditions | Privacy Policy

粤ICP备16008861号

Copyright © 2016-2018 Drugdu.com. All Rights Reserved.