Exposure to endocrine-disrupting chemicals in early life, including during gestation and infancy, results in a higher preference for sugary and fatty foods later in life, according to an animal study being presented Sunday at ENDO 2025, the Endocrine Society’s annual meeting in San Francisco, Calif. Endocrine-disrupting chemicals are substances in the environment (air, soil or water supply), food sources, personal care products and manufactured products that interfere with the normal function of the body’s endocrine system. To determine if early-life exposure to these chemicals affects eating behaviors and preferences, researchers from the University of Texas at Austin conducted a study of 15 male and 15 female rats exposed to a common mixture of these chemicals during gestation or infancy. “Our research indicates that endocrine-disrupting chemicals can physically alter the brain’s pathways that control reward preference and eating behavior. These results may partially explain increasing rates of obesity around the world,” ...
Organiser: Nanchang Municipal People’s Government, Chinese Research Hospital Association Time:August 21–23, 2025 address:No. 1315 Huaiyushan Avenue, Honggutan New District, Nanchang City Exhibition hall:Nanchang Greenland International Expo Center Product range: Cardio-cerebrovascular Monitoring Equipment: EEG machines, EMG machines, ECG machines, evoked potential devices, remote monitoring systems, HOLTER monitors, defibrillator monitors, exercise treadmill ECG systems, ambulatory blood pressure monitors, oximeters, and auxiliary diagnostic devices. Medical Materials and Supplies: Various medical consumables, enamel and glassware, dressing rubber products, disposable items, reagents, clinical laboratory equipment, and blood transfusion supplies. Clinical Laboratory Equipment: Medical incubators, centrifuges, microscopes, pre-analytical processing equipment, and body fluid handling devices. Biochemical Analysis Instruments: Automatic biochemical analyzers, hematology analyzers, hemodialysis machines, blood gas analyzers, microbiology analyzers, urinalysis analyzers, flow cytometers, electrolyte analyzers, ELISA readers, chromatographs, PCR machines, DNA synthesizers, laboratory instruments, apparatus, and supplies. Blood Transfusion Equipment: Blood testing devices, refrigeration equipment, blood collection and supply instruments, blood bank equipment, blood bank ...
Kangyuan Pharmaceutical announced that the company recently received the “Drug Clinical Trial Approval Notice” for the Class 1 chemical new drug KYS2301 gel (three specifications) issued by the National Medical Products Administration. KYS2301 gel is the world’s first peptide inhibitor targeting the CCR8 target, and its indication is atopic dermatitis. Preclinical studies have shown that KYS2301 has a high affinity for the CCR8 target, and topical application of KYS2301 gel has a good pharmacodynamic effect on the treatment of atopic dermatitis. Toxicology and pharmacokinetic studies have shown that KYS2301 gel is highly safe. At present, the treatment drugs for atopic dermatitis mainly include topical corticosteroids, which have many adverse reactions and are not suitable for long-term use. The development of localized atopic dermatitis treatment drugs with better safety has important clinical significance. https://www.nbd.com.cn/articles/2025-07-03/3932088.html
Recently , Innovent’s innovative drug subsidiary, Innovent, announced that its new generation of anti-angiogenesis (anti-VEGF antibody) first-class biological new drug Enzeshu (generic name: Suvicitamab for injection) developed in China has been officially approved for marketing by the China National Medical Products Administration. Enzeshu is approved for the treatment of recurrent ovarian cancer, fallopian tube cancer or primary peritoneal cancer in adults who have received no more than one systemic treatment after platinum resistance in combination with paclitaxel, liposome doxorubicin or topotecan. It is reported that Enzeshu is the first targeted drug in my country to obtain indications for the entire population of platinum-resistant ovarian cancer, breaking the dilemma of limited treatment options in this field. In recent years, the innovative transformation of the old pharmaceutical company Innovent Biologics has begun to show results. The company currently has 10 innovative drugs on the market, and 8 of them have been approved ...
Recently , CStone Pharmaceuticals announced that it has reached an exclusive strategic cooperation with Istituto Gentili (hereinafter referred to as Gentili) on the commercialization of Sugemalimab in Western Europe and the United Kingdom. Gentili has obtained the exclusive commercialization rights of Sugemalimab in 23 countries, and CStone Pharmaceuticals will receive a payment of up to US$192.5 million, including an initial payment, registration and sales milestone payments, and a revenue share of nearly 50% of the net sales of Sugemalimab in the authorized area. This cooperation shows that CStone Pharmaceuticals’ products have been recognized in the international market, which will help enhance its influence in the field of global cancer treatment. In the long run, this cooperation will enhance investors’ confidence in the company’s future growth and lay the foundation for the company to further expand its overseas market. https://www.nbd.com.cn/articles/2025-07-08/3936641.html
With Kangfang Biopharma’s successful challenge to PD-1 monoclonal antibody with Ivoside, tumor immunotherapy (IO) has rapidly evolved to the 2.0 era. PD-(L)1/VEGF bispecific antibodies have been snapped up by MNCs, and PD-(L)1/VEGF trispecific antibodies have gradually become a research and development trend, indicating that tumor treatment is accelerating towards multi-target synergy. Recently, CStone Pharmaceuticals announced the latest clinical progress of its independently developed potential first-in-class/best-in-class CS2009 (PD-1/VEGF/CTLA-4 trispecific antibody). The drug has balanced monovalent PD-1 and CTLA-4 binding arms and bivalent VEGFA binding arms, which can produce strong multi-target synergistic effects and preferentially target tumor tissues to reduce systemic toxicity. The global multi-center Phase I/II clinical study of CS2009 is actively recruiting patients in Australia and China, and plans to expand to the United States for Phase II enrollment. Currently, the trial enrollment is very rapid, and the number of patients is expected to exceed 100 by the end of ...
According to industrial and commercial information, in May 2025, Roche Biopharmaceuticals (Suzhou/Shanghai) Co., Ltd. (Roche Accelerator Member) has completed a new round of market-oriented financing . The new financing came from Jianfa Emerging Investment, Suzhou Angel Fund, Xinxi Capital, and Qisheng Capital. Just a few months ago, in October 2024, Shize Bio officially announced the completion of more than 100 million yuan in B1 round of market-oriented financing : the B1 round of financing was led by Tailong/Taikun Capital, co-invested by Qisheng Capital and Tianhui Capital, and additional investments from old shareholders such as Frees Capital, Qiming Venture Partners, Lilly Asia Fund, and Sequoia China. The B1 round of financing will be used to improve Shize Bio’s clinical-grade iPS-derived cell drug pipeline for the treatment of neurological diseases, further conduct clinical research, and promote multiple registered clinical trials. During the overall downturn of the pharmaceutical industry from 2022 to 2025, ...
Recently, Henlius has made another important progress in the global development of its innovative programmed death-ligand 1 (PD-L1) antibody-drug conjugate (ADC) injection HLX43. The product has been approved by the China National Medical Products Administration (NMPA), the U.S. Food and Drug Administration (FDA), the Australian Therapeutic Goods Administration (TGA) and the Japanese Pharmaceuticals and Medical Devices Agency (PMDA) to conduct an international multicenter Phase II clinical study for advanced non-small cell lung cancer (NSCLC), and the first subject has been dosed in China. No similar ADC product targeting PD-L1 has been approved for marketing in the world, and HLX43 is the world’s first PD-L1 ADC to enter Phase II clinical trials. According to the latest data from GLOBOCAN, lung cancer is the cancer with the highest morbidity and mortality in the world. In 2022, there will be more than 2.48 million new cases of lung cancer worldwide, accounting for 12.4% ...
On July 10, United Pharmaceutical (03933) issued an announcement, announcing that its wholly-owned subsidiary United Biotech received approval from the U.S. FDA on July 4, 2025 to register its Class 1 innovative drugUBT37034 injection is used in clinical trials for the indication of overweight or obesity. The drug was developed by Federal Biotechnology and has independent intellectual property rights.It is a new type of peptide receptor agonist that can reduce body weight by selectively acting on neuropeptide Y2 receptors. The announcement mentioned that preclinical animal model studies of UBT37034 showed that it can significantly reduce body weight when used in combination with GLP-1 analogs. The company said it will continue to focus on new product research and development, enhance its competitiveness and creativity in the biopharmaceutical industry, and is expected to create greater benefits for the company and its shareholders. https://finance.eastmoney.com/a/202507103453263675.html
On July 10, SINOPHARM (01177) announced that the Group’s independently developed CDK2/4/6 inhibitor Cumocillin Capsules “TQB3616” combined with Fulvestrant Injection for previously untreated HR-positive, HER2-negative (HR+/HER2-) locally advanced or metastatic breast cancer has been submitted to the Center for Drug Evaluation of the China National Medical Products Administration for new indications for marketing approval and has been accepted. The approval of the first-line indication application further confirms the broad potential of this combination therapy in different treatment stages of advanced breast cancer. In addition, the new drug application for Cumosili submitted by the Group in July 2024 has also been accepted by the CDE for use in combination with Fulvestrant for the treatment of HR+/HER2- locally advanced or metastatic breast cancer that has been previously treated with endocrine therapy. The announcement mentioned that breast cancer is one of the most common malignant tumors in women, of which HR+/HER2- breast cancer ...
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