Incyte Pharma Drug Shows Positive Effect in Treatment of a Certain Type of Blood Cancer

December 9, 2025  Source: drugdu 34

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Incyte Pharma states new clinical data shows its monoclonal antibody drug INCA033989 can rapidly and significantly reduce spleen volume, alleviate associated symptoms, and improve anemia in patients with myelofibrosis who have a specific genetic mutation. The preliminary research results come from treating patients with CALR mutation (mutCALR) myelofibrosis with the drug as monotherapy and in combination with ruxolitinib. The drug demonstrated good safety, with no dose-limiting toxicities reported. Incyte Pharma plans to initiate a registration program for myelofibrosis treatment in 2026.


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