On September 5, 2024, Colder Products Company (CPC) launched a new sterile micro connector, which is the first connector that can be directly loaded into a freezer and is used in cell and gene therapy (CGT) processes. The MicroCNX ® ULT series can be frozen to -190 ° C and is compatible with the most commonly used types of tubing for developing cutting-edge therapies, including polyvinyl chloride (PVC) tubing.

In order to meet the needs of cell viability, shelf life, and transportation, many cell therapy processes are lowered to a temperature range of -150 º C or lower, "said Troy Ostreng, Senior Product Manager of CPC Biopharmaceutical Business.

The MicroCNX ® ULT connector is designed to provide a simple and efficient method for achieving sterile connections in pipelines used for small cell therapy and gene therapy components. This connector does not require additional piping in the process, thus helping to reduce product retention and loss.

The MicroCNX ® ULT series ends and channels are made of polyphenylene sulfone (PPSU), a high-performance polymer that has good chemical compatibility with harsh chemicals used in cryopreservation processes, such as dimethyl sulfoxide (DMSO).

This new series of products is built on CPC's pioneering work in creating the smallest connector for biopharmaceuticals, the 1/8-inch MicroCNX ® The series connector is currently the only one that can completely replace thermoplastic pipe welding in small volume piping systems to achieve a closed aseptic connection solution. Compared to early MicroCNX ® Similar to the product, the MicroCNX ® ULT series features a 1/8-inch flow channel and can choose from 1/8-inch, 3/32 inch, or 1/16 inch hose hook tips to support the use of various pipe sizes and materials such as PVC, silicone, and thermoplastic elastomer (TPE).

In June, CPC also launched MicroCNX ® Ruhr connector. Manufacturers who frequently use Ruhr connectors greatly appreciate the flexibility provided by this new product in creating sterile connections outside of biosafety cabinets.

Ostreng said, "As a leader in aseptic connection technology, our goal is to scale up with our customers and help them easily create aseptic connections from the laboratory stage to commercialization.

In addition to providing the industry's smallest MicroCNX ® In addition to the series of sterile connectors, CPC also produces the largest sterile connector - AseptiQuik ® W series. The applications of AseptiQuik ® W connectors include high-capacity (up to 5000 liters) fluid transport and filtration processes (such as culture media, buffer solutions, and cell culture processes).
CPC already has the widest portfolio of sterile connector products. MicroCNX ® ULT connectors are just another example of our continuous innovation to meet the evolving needs of global cell therapy, gene therapy, and biopharmaceutical manufacturers, "Ostreng said.

Source: https://pharm.jgvogel.cn/c1441047.shtml