How the brain is able to store memories over long periods of time has been a persistent mystery to neuroscientists. In a new study, researchers from the Centre for Integrative Neuroplasticity (CINPLA) at the University of Oslo show that long-lived extracellular matrix molecules called perineuronal nets are essential for distant memories.
New research published in the Journal of Experimental Medicine highlights the pernicious effect of obesity on the long-term health of blood-making stem cells (hematopoietic stem cells).
Analysts and investors think Perjeta’s end-of-the-year indication may not be as lucrative as they once hoped. The FDA green-lighted the drug in tandem with giant Herceptin and chemo for HER2-positive, post-surgery breast cancer patients with a high risk of recurrence. Patients should receive up to 18 cycles of the regimen over the course of one year, according to the indication.
Mallinckrodt, which has landed in hot water multiple times this year, is diversifying beyond its controversial lead seller.
A 10-month-old boy born without an immune system has been confined to his sanitized home his entire life and only leaves for doctor's visits. Sebastian Romero was diagnosed with severe combined immunodeficiency (SCID) at two weeks old, a rare genetic disorder known as 'bubble boy' disease that left him with no infection-fighting cells.
About half of all cases of deafness are caused by genetic defects. So it’s no surprise that the emerging gene-editing technique CRISPR-Cas9 is being examined closely for its potential to prevent hearing loss in people who inherit those genes. Scientists at the Howard Hughes Medical Institute are among those looking to deploy CRISPR in genetic deafness—and they have their first evidence that their technique may hold promise.
New US research has found that being married may have a protective effect for patients who have suspected or confirmed heart disease, with those who are unmarried, divorced, or widowed all at a higher risk of death than married patients.
Short-term exposures to fine particulate air pollution and ozone—even at levels well below current national safety standards—were linked to higher risk of premature death among the elderly in the U.S. according to a new study from Harvard T.H. Chan School of Public Health.
Gene expression in specific cells and in specific regions can provide a more precise, neuroprotective approach than traditional treatments for neurological diseases. For multiple sclerosis, specifically, increasing cholesterol synthesis gene expression in astrocytes of the spinal cord can be a pathway to repair nerves that affect walking.
Video game addicts of the world: Your compulsion may be considered an official mental disorder. The World Health Organization (WHO) is preparing to include it its new global medical coding guidelines.
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