Dystrophin is a major protein involved in the functionality of muscles. If a mutation occurs, the production of dystrophin becomes inhibited which leads to the development of Duchenne muscular dystrophy (DMD). DMD usually leads to muscle or heart failure, followed by premature death. There was no effective treatment available till date.
In a bid to better handle the prescription and workflow processes of a practice, the orthopedic surgeons at Affiliated Oral and Maxillofacial Surgeons of Maryland have come up with a fresh mobile medication management application which allows each doctor to write about 30 prescriptions per day for controlled substances, including opioids for pain management.
Biopharma Sarepta Therapeutics and Brammer Bio enter into a long-term strategic partnership to design and develop new manufacturing facilities at CDMO’s plant in Massachusetts. The new partnership is for the development of the production of its microdystrophin, Duchenne Muscular Dystrophy (DMD) therapy and future gene therapies.
Pfizer Inc. has initiated a Phase 1b clinical trial for its mini-dystrophin gene therapy candidate, PF-06939926, in boys with Duchenne muscular dystrophy (DMD). The first boy received an infusion of the mini-dystrophin gene on March 22nd, administered under the supervision of principal investigator, Edward Smith, MD, Associate Professor of Pediatrics and Neurology at Duke University Medical Center.
The movement within the wearable market is very clear. Demand makes that wearables are becoming less expensive and increasingly commoditized. Just better sensors are now no longer enough. Wearables need to be smarter and more useful. They need to analyze multiple data at once, or so to say, be more holistic. To do so, many wearable makers all over the world are focusing on AI-powered devices.
Tokyo-based Astellas Pharma is buying Cambridge, Mass.-based Mitobridge for a total of $390 million. Astellas is pulling the trigger on an acquisition option from a partnership deal the two companies formed in 2013. Under that deal, the two companies collaborated on discovering and developing drugs that target mitochondrial function. The most advanced program from the collaboration is MA-0211, which is presently in Phase I clinical trials for Duchenne muscular dystrophy (DMD). Astellas is an equity investor in Mitobridge already, and is paying $165.5 million in cash in addition to the $60 million in equity it already owns. There is also an additional $225 million in potential milestone payments. John Carroll, with Endpoints News, writes, “For years now, Salk’s Ron Evans—a celebrated serial entrepreneur in scientific circles—has been concentrating on the potential of a new pathway for turning your average couch potato rodent into Mighty Mouse—without exercise…. A couple of ...
your submission has already been received.
Please enter a valid Email address！
The most relevant industry news & insight will be sent to you every two weeks.