Spironolactone – An Alternative to Antibiotics In Acne Treatment

June 12, 2018  Source: Science Daily 143

Acne is a condition which affects nearly 85 percent of people. Higher doses of oral antibiotics are often prescribed by dermatologists for acne treatment.

A research team from Perelman School of Medicine at the University of Pennsylvania have found that the diuretic drug named spironolactone, might be effective equivalent to antibiotics in order to treat acne. Spironolactone is generally prescribed for high blood pressure and fluid build-up.

The lead author cum chief resident in dermatology department named John S. Barbieri said, "It's clear that a safe alternative to oral antibiotics could have a huge benefit, and our data show spironolactone may be that alternative,"

Spironolactone was prescribed to treat high blood pressure and heart failure. The anti-hormonal effect of spironolactone helps in preventing acne outbreaks among women. Even in men, androgen levels are kept under control due to the consumption of spironolactone.

John S. Barbieri suggested, "Dermatologists should consider spironolactone first instead of antibiotics when it comes to women with acne. Spironolactone may have a better safety profile than oral antibiotics, which is another factor that makes it such an appealing option."

Though spironolactone is less expensive, it has still not been approved for acne treatment by the U.S. Food and Drug Administration in spite of expert opinions supporting its effectiveness.

By Ddu
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